AutismKB 2.0

Annotation Detail for PTGFRN


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Basic Information Top
Gene Symbol:PTGFRN ( CD315,CD9P-1,EWI-F,FLJ11001,FPRP,KIAA1436,SMAP-6 )
Gene Full Name: prostaglandin F2 receptor negative regulator
Band: 1p13.1
Quick LinksEntrez ID:5738; OMIM: 601204; Uniprot ID:FPRP_HUMAN; ENSEMBL ID: ENSG00000134247; HGNC ID: 9601
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
44N-linked (GlcNAc...).
286N-linked (GlcNAc...).
300N-linked (GlcNAc...).
383N-linked (GlcNAc...).
413N-linked (GlcNAc...).
427Endoplasmic reticulum retention signal.
525N-linked (GlcNAc...).
600N-linked (GlcNAc...).
618N-linked (GlcNAc...).
691N-linked (GlcNAc...).
705Cell attachment site (Potential).
875Phosphoserine.
Location(AA) Modifications Resource
44N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
286N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
300N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
383N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
413N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
525N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
600N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
618N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
691N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
6Phosphoserine(PKA)HMM predict
44N-linkedHMM predict
48Phosphotyrosine(INSR)HMM predict
121O-linkedHMM predict
123O-linkedHMM predict
124O-linkedHMM predict
150O-linkedHMM predict
173O-linkedHMM predict
195Phosphoserine(PKG)HMM predict
235O-linkedHMM predict
239Phosphoserine(PKG)HMM predict
300N-linkedHMM predict
316Phosphoserine(IKK)HMM predict
338Phosphoserine(CK1)HMM predict
342Phosphoserine(CK1)HMM predict
383N-linkedHMM predict
395Phosphoserine(CDC2)HMM predict
395Phosphoserine(CDK)HMM predict
411Phosphotyrosine(Syk)HMM predict
413N-linkedHMM predict
444Phosphothreonine(PKC)HMM predict
525N-linkedHMM predict
526N-linkedHMM predict
527Phosphoserine(PKB)HMM predict
527Phosphoserine(PKA)HMM predict
600N-linkedHMM predict
618N-linkedHMM predict
653Phosphotyrosine(INSR)HMM predict
674Phosphoserine(IKK)HMM predict
691N-linkedHMM predict
767Phosphoserine(CK1)HMM predict
796O-linkedHMM predict
801Phosphoserine(CDC2)HMM predict
858S-palmitoylHMM predict
859S-palmitoylHMM predict
866Phosphothreonine(PKC)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_020440
  • Location:chr1 117254211-117334494
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
FOXA1 MCF7GSE15244 117244873 117245506 633 9022
Oct1 HelaGSE14283 117246172 117246212 40 8020
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T30-glioblastomaGSE21026 117334415 117335863 1448 645
P300 T30-glioblastomaGSE21026 117333767 117335466 1699 122
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 117254254 117254771 517 0
CTCF G2GSE9613 117288711 117289087 376 0
CTCF G2GSE9613 117328759 117329087 328 0
ER MCF7GSE19013 117263767 117264578 811 0
H3K4me3 colorectalcancer 117255311 117255601 290 0
H3ac HepG2E 117255100 117255703 603 0
H3ac HepG2E 117261182 117261536 354 0
Nanog hESGSE18292 117293881 117294160 279 0
Oct1 H2O2-HelaGSE14283 117317748 117317777 29 0
Oct1 HelaGSE14283 117316728 117316764 36 0
Oct1 HelaGSE14283 117317748 117317777 29 0
Rb GrowingGSE19898 117285386 117285551 165 0
TAF k562GSE8489 117254988 117256262 1274 0
TAF k562GSE8489 117334164 117334565 401 0
hScc1 BcellGSE12603 117254146 117254838 692 0
hScc1 BcellGSE12603 117293369 117293507 138 0
hScc1 BcellGSE12603 117330786 117330996 210 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-let-7b hsa-let-7b 22 18668040
hsa-let-7b* hsa-let-7b 22 18668040
hsa-miR-1 hsa-mir-1-2 18 18668040
hsa-miR-1 hsa-mir-1-1 20 18668040
hsa-miR-155 hsa-mir-155 21 18668040
hsa-miR-155* hsa-mir-155 21 18668040
hsa-miR-16 hsa-mir-16-1 13 18668040
hsa-miR-16 hsa-mir-16-2 3 18668040
hsa-miR-30a hsa-mir-30a 6 18668040
hsa-miR-30a* hsa-mir-30a 6 18668040
hsa-miR-30b hsa-mir-30b 8 18668040
hsa-miR-30b* hsa-mir-30b 8 18668040
hsa-miR-30c hsa-mir-30c-2 6 18668040
hsa-miR-30c hsa-mir-30c-1 1 18668040
hsa-miR-30c-1* hsa-mir-30c-1 1 18668040
hsa-miR-30c-2* hsa-mir-30c-2 6 18668040
hsa-miR-30d hsa-mir-30d 8 18668040
hsa-miR-30d* hsa-mir-30d 8 18668040
hsa-miR-30e hsa-mir-30e 1 18668040
hsa-miR-30e* hsa-mir-30e 1 18668040
ID in Tarbase Data Type Support Type miRNA Gene Direct Support Publication
1267 Unknown pSILAC miR-30 PTGFRN down 50-25% 18668040
Ensembl Protein Type Differentially expressed in Pathology or Event Mis Regulation Gene Expression Tumour Involvement
ENSG00000134247 n_a n_a n_a n_a n_a
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018