AutismKB 2.0

Annotation Detail for PLEKHG1


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Basic Information Top
Gene Symbol:PLEKHG1 ( ARHGEF41,FLJ31738,KIAA1209 )
Gene Full Name: pleckstrin homology domain containing, family G (with RhoGef domain) member 1
Band: 6q25.1
Quick LinksEntrez ID:57480; OMIM: NA; Uniprot ID:PKHG1_HUMAN; ENSEMBL ID: ENSG00000120278; HGNC ID: 20884
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
1150Phosphoserine.
1192Phosphoserine.
1245Phosphoserine.
Location(AA) Modifications Resource
1150Phosphoserine.Swiss-Prot 53.0
Location(AA) Modification Resource
11Phosphoserine(IKK)HMM predict
15O-linkedHMM predict
20O-linkedHMM predict
64Phosphoserine(CDK)HMM predict
108Phosphoserine(MAPK)HMM predict
234Phosphothreonine(PKC)HMM predict
273Phosphotyrosine(Syk)HMM predict
469Phosphoserine(PKG)HMM predict
469Phosphoserine(PKB)HMM predict
469Phosphoserine(IKK)HMM predict
472Phosphoserine(CK1)HMM predict
492Phosphoserine(PKG)HMM predict
501O-linkedHMM predict
506PhosphoserineHMM predict
506Phosphoserine(CDK)HMM predict
512Phosphoserine(ATM)HMM predict
512Phosphoserine(IKK)HMM predict
548Phosphoserine(CDC2)HMM predict
559Phosphotyrosine(EGFR)HMM predict
559SulfotyrosineHMM predict
559Phosphotyrosine(Syk)HMM predict
572N-linkedHMM predict
599Phosphoserine(CK1)HMM predict
610Phosphoserine(PKG)HMM predict
610Phosphoserine(PKA)HMM predict
610Phosphoserine(PKA)HMM predict
610Phosphoserine(CK2)HMM predict
610PhosphoserineHMM predict
611Phosphoserine(PKB)HMM predict
611Phosphoserine(PKG)HMM predict
661Phosphotyrosine(Syk)HMM predict
681Phosphoserine(CK1)HMM predict
681O-linkedHMM predict
682Phosphothreonine(CDK)HMM predict
682Phosphothreonine(MAPK)HMM predict
728Phosphoserine(ATM)HMM predict
742Phosphotyrosine(SRC)HMM predict
742Phosphotyrosine(INSR)HMM predict
742Phosphotyrosine(Syk)HMM predict
793Phosphoserine(CK2)HMM predict
793Phosphoserine(CK2)HMM predict
803Phosphothreonine(PKA)HMM predict
808Phosphotyrosine(Syk)HMM predict
815Phosphoserine(CDC2)HMM predict
832Phosphoserine(CK1)HMM predict
845Phosphotyrosine(INSR)HMM predict
877Phosphothreonine(CDK)HMM predict
877Phosphothreonine(MAPK)HMM predict
892Phosphoserine(CK1)HMM predict
896Phosphoserine(ATM)HMM predict
901Phosphothreonine(MAPK)HMM predict
901Phosphothreonine(CDK)HMM predict
923Phosphoserine(CK1)HMM predict
955Phosphoserine(ATM)HMM predict
1007Phosphoserine(ATM)HMM predict
1050Phosphoserine(CDC2)HMM predict
1066Phosphoserine(CK1)HMM predict
1072Phosphoserine(IKK)HMM predict
1072Phosphoserine(CAMK2)HMM predict
1074Phosphoserine(ATM)HMM predict
1124O-linkedHMM predict
1131O-linkedHMM predict
1175Phosphoserine(ATM)HMM predict
1178Phosphotyrosine(Jak)HMM predict
1181Phosphoserine(ATM)HMM predict
1183Phosphoserine(CK1)HMM predict
1186Phosphoserine(CK1)HMM predict
1190N-linkedHMM predict
1280Phosphotyrosine(Syk)HMM predict
1280Phosphotyrosine(INSR)HMM predict
1280SulfotyrosineHMM predict
1280Phosphotyrosine(EGFR)HMM predict
1290Phosphoserine(CK1)HMM predict
1302Phosphoserine(PKB)HMM predict
1302Phosphoserine(PKG)HMM predict
1326Phosphoserine(CDC2)HMM predict
1329Phosphothreonine(CDK)HMM predict
1329Phosphothreonine(CDC2)HMM predict
1381Phosphoserine(CDK)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001029884
  • Location:chr6 150962691-151206491
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
NRSF mAbJurkat 150947641 150947911 270 14916
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 151178037 151178320 283 0
CTCF CD4SISSRdata 151178037 151178320 283 0
CTCF G2GSE9613 150962570 150963669 1099 0
CTCF G2GSE9613 151045067 151045888 821 0
CTCF G2GSE9613 151174782 151175812 1030 0
CTCF G2GSE9613 151178053 151178223 170 0
CTCF G2GSE9613 151179958 151180239 281 0
CTCF G2GSE9613 151180732 151180912 180 0
CTCF G2GSE9613 151194290 151194918 628 0
FOXA1 MCF7GSE15244 151190657 151191198 541 0
NFkBII GM12878GSE19485 150993897 150996621 2724 0
NFkBII GM12878GSE19485 150996924 151000849 3925 0
NFkBII GM12878GSE19485 151175977 151178674 2697 0
NFkBII GM12892GSE19485 150999102 151000442 1340 0
Nanog hESGSE18292 151116162 151116676 514 0
Nanog hESGSE18292 151178060 151178241 181 0
Oct4 hESGSE17917 151180746 151180937 191 0
RARA MCF7GSE15244 151083603 151084134 531 0
RARA MCF7GSE15244 151190477 151191198 721 0
Rb SenescentGSE19898 151176194 151176610 416 0
Rb SenescentGSE19898 151178008 151178186 178 0
TAF HelaGSE8489 151191942 151192123 181 0
TFAP2C MCF7GSE21234 151086733 151087206 473 0
TFAP2C MCF7GSE21234 151169682 151169979 297 0
hScc1 BcellGSE12603 150962502 150963669 1167 0
hScc1 BcellGSE12603 151045031 151045703 672 0
hScc1 BcellGSE12603 151048820 151049168 348 0
hScc1 BcellGSE12603 151177891 151178223 332 0
hScc1 CdLSGSE12603 150962502 150963958 1456 0
hScc1 CdLSGSE12603 151177855 151178317 462 0
hScc1 CdLSGSE12603 151180732 151181181 449 0
hScc1 G2GSE9613 151176322 151176913 591 0
hScc1 G2GSE9613 151177891 151178223 332 0
hScc1 G2GSE9613 151180732 151181146 414 0
p63 keratinocytesGSE17611 151044485 151045288 803 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
23316 mRNA PLEKHG1 chr6 151134337 151244899 2239 EST chr6 151173252 151175491 Non-exonic Bidirectional (NOB) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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