AutismKB 2.0

Annotation Detail for INTS2


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Basic Information Top
Gene Symbol:INTS2 ( INT2,KIAA1287 )
Gene Full Name: integrator complex subunit 2
Band: 17q23.2
Quick LinksEntrez ID:57508; OMIM: 611346; Uniprot ID:INT2_HUMAN; ENSEMBL ID: ENSG00000108506; HGNC ID: 29241
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
848Phosphotyrosine.
849Phosphothreonine.
Location(AA) Modifications Resource
Location(AA) Modification Resource
63Phosphoserine(IKK)HMM predict
100Phosphoserine(IKK)HMM predict
100Phosphoserine(CK1)HMM predict
133Phosphoserine(CK2)HMM predict
135PhosphoserineHMM predict
135Phosphoserine(CDC2)HMM predict
240Phosphoserine(CK1)HMM predict
247Phosphothreonine(PKA)HMM predict
259Phosphoserine(ATM)HMM predict
282Phosphothreonine(PKC)HMM predict
331Phosphothreonine(PKA)HMM predict
331Phosphothreonine(PKC)HMM predict
332Phosphoserine(CK1)HMM predict
334Phosphoserine(CK1)HMM predict
353Phosphothreonine(PKC)HMM predict
445Phosphothreonine(CDK)HMM predict
469O-linkedHMM predict
475Phosphoserine(IKK)HMM predict
547N-linkedHMM predict
565Phosphoserine(PKB)HMM predict
565Phosphoserine(PKA)HMM predict
567Phosphothreonine(PKC)HMM predict
586Phosphothreonine(CDK)HMM predict
610Phosphoserine(IKK)HMM predict
678Phosphoserine(IKK)HMM predict
680Phosphoserine(IKK)HMM predict
751N-linkedHMM predict
767N-linkedHMM predict
907N-linkedHMM predict
908N-linkedHMM predict
972O-linkedHMM predict
1020Phosphotyrosine(EGFR)HMM predict
1123Phosphoserine(CK1)HMM predict
1169Phosphotyrosine(INSR)HMM predict
1171N-linkedHMM predict
1176Phosphothreonine(PKA)HMM predict
1178Phosphoserine(PKA)HMM predict
1198N-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_020748
  • Location:chr17 57297512-57360158
  • strand:-
No data
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3ac HepG2E 57358186 57360280 2094 0
P300 T30-glioblastomaGSE21026 57359364 57360578 1214 0
PHF8 293TGSE20725 57359219 57360521 1302 0
PHF8 HeLaGSE20725 57359232 57360698 1466 0
PHF8 Hs68plusFBSGSE20725 57358975 57360549 1574 0
PolII HeLaGSE12783 57358974 57360514 1540 0
RARA MCF7GSE15244 57339537 57340042 505 0
RARA MCF7GSE15244 57359194 57360519 1325 0
RARG MCF7GSE15244 57359272 57360280 1008 0
Rb QuiescentGSE19898 57359638 57359746 108 0
TAF HelaGSE8489 57358735 57360169 1434 0
TAF k562GSE8489 57358272 57360519 2247 0
TAFII hESGSE17917 57359653 57360300 647 0
p130 QuiescentGSE19898 57359704 57360171 467 0
p130 SenescentGSE19898 57359414 57360363 949 0
p130 shRbQuiescentGSE19898 57359346 57360550 1204 0
p130 shRbSenescentGSE19898 57359522 57360288 766 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018