AutismKB 2.0

Annotation Detail for PTK6


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:PTK6 ( BRK,FLJ42088 )
Gene Full Name: PTK6 protein tyrosine kinase 6
Band: 20q13.33
Quick LinksEntrez ID:5753; OMIM: 602004; Uniprot ID:PTK6_HUMAN; ENSEMBL ID: ENSG00000101213; HGNC ID: 9617
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
114Phosphotyrosine.
159Phosphoserine.
342Phosphotyrosine; by autocatalysis (By
447Phosphotyrosine.
Location(AA) Modifications Resource
342Phosphotyrosine (by autocatalysis) (Bysimilarity).Swiss-Prot 53.0
342Phosphotyrosine (Brk)Phospho.ELM 6.0
351PhosphotyrosinePhospho.ELM 6.0
447Phosphotyrosine.Swiss-Prot 53.0
447Phosphotyrosine (Brk)Phospho.ELM 6.0
Location(AA) Modification Resource
72Phosphothreonine(PKC)HMM predict
97N-linkedHMM predict
114Phosphotyrosine(Jak)HMM predict
159Phosphoserine(PKG)HMM predict
159Phosphoserine(CK1)HMM predict
308Phosphotyrosine(INSR)HMM predict
435LysineHMM predict
438ArginineHMM predict
447Phosphotyrosine(INSR)HMM predict
447Phosphotyrosine(Syk)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_005975
  • Location:chr20 61630221-61639150
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 61639697 61640063 366 730
CTCF CD4SISSRdata 61639697 61640063 366 730
CTCF JurkatGSE12889 61639744 61640014 270 729
CTCF G2GSE9613 61639504 61640307 803 755
NFkBII GM18526GSE19485 61638844 61640629 1785 586
P300 T0-glioblastomaGSE21026 61639345 61640116 771 580
P300 T30-glioblastomaGSE21026 61639249 61640123 874 536
TFAP2C MCF7GSE21234 61638011 61640394 2383 52
TFAP2C MCF7GSE21234 61640408 61641242 834 1675
hScc1 BcellGSE12603 61638406 61640233 1827 169
hScc1 G2GSE9613 61639406 61640821 1415 963
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 61635874 61636317 443 0
TAF HelaGSE8489 61633445 61633878 433 0
hScc1 BcellGSE12603 61631399 61632576 1177 0
hScc1 BcellGSE12603 61634253 61634615 362 0
hScc1 BcellGSE12603 61635212 61636209 997 0
hScc1 BcellGSE12603 61636465 61636833 368 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018