AutismKB 2.0

Annotation Detail for NLGN2


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Basic Information Top
Gene Symbol:NLGN2 ( KIAA1366 )
Gene Full Name: neuroligin 2
Band: 17p13.1
Quick LinksEntrez ID:57555; OMIM: 606479; Uniprot ID:NLGN2_HUMAN; ENSEMBL ID: ENSG00000169992; HGNC ID: 14290
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
98N-linked (GlcNAc...) (Potential).
136N-linked (GlcNAc...) (Potential).
522N-linked (GlcNAc...) (Potential).
713Phosphoserine (By similarity).
Location(AA) Modifications Resource
98N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
136N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
522N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
713Phosphoserine (By similarity).Swiss-Prot 53.0
Location(AA) Modification Resource
16MethylarginineHMM predict
74Phosphotyrosine(Abl)HMM predict
92Phosphoserine(IKK)HMM predict
98N-linkedHMM predict
143Phosphotyrosine(Syk)HMM predict
264Phosphoserine(CDK)HMM predict
322PhosphoserineHMM predict
397Phosphoserine(CK2)HMM predict
397Phosphoserine(CK1)HMM predict
418Phosphotyrosine(Abl)HMM predict
450Phosphothreonine(PKA)HMM predict
474SulfotyrosineHMM predict
619O-linkedHMM predict
640O-linkedHMM predict
640Phosphothreonine(PKC)HMM predict
662Phosphotyrosine(EGFR)HMM predict
672SulfotyrosineHMM predict
673Phosphoserine(IKK)HMM predict
673Phosphoserine(CK1)HMM predict
679O-linkedHMM predict
718O-linkedHMM predict
720O-linkedHMM predict
805O-linkedHMM predict
818O-linkedHMM predict
823N-linkedHMM predict
824N-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_020795
  • Location:chr17 7252225-7263902
  • strand:+
No data
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 7252398 7252950 552 0
Oct1 HelaGSE14283 7259283 7259312 29 0
hScc1 BcellGSE12603 7253093 7253304 211 0
hScc1 BcellGSE12603 7262385 7262536 151 0
p130 SenescentGSE19898 7257417 7257678 261 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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