Annotation Detail for ARHGAP21

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Basic Information Top

Gene Symbol:	ARHGAP21 ( ARHGAP10,DKFZp761L0424,FLJ33323,FLJ90108 )
Gene Full Name:	Rho GTPase activating protein 21
Band:	10p12.1
Quick Links	Entrez ID:57584; OMIM: 609870; Uniprot ID:RHG21_HUMAN; ENSEMBL ID: ENSG00000107863; HGNC ID: 23725
Relate to Another Database:	SFARIGene; denovo-db

Post Translation Modification

Location(AA)	Modification
35	Phosphoserine (By similarity).
458	Phosphoserine.
474	Phosphoserine.
476	Phosphoserine.
880	Phosphoserine (By similarity).
923	Phosphoserine.
1089	Phosphoserine.
1098	Phosphoserine (By similarity).
1219	Phosphoserine.
1220	Phosphoserine.
1239	Phosphotyrosine.
1282	Phosphothreonine.
1377	Phosphoserine.
1382	Phosphoserine.
1430	Phosphoserine.
1431	Phosphoserine.
1432	Phosphoserine.
1526	Phosphoserine.
1668	Phosphoserine.

Validated transcription factor binding site by ChIP-Chip and ChIP-Seq

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
Fos	K562	GSE19551	25053139	25053962	823	1001
RARG	MCF7	GSE15244	25064280	25064515	235	11848
Rb	Quiescent	GSE19898	25053274	25053542	268	859
Rb	Senescent	GSE19898	25053034	25053835	801	885
hScc1	Bcell	GSE12603	25053549	25053791	242	1121
hScc1	CdLS	GSE12603	25052856	25053791	935	774
p130	Senescent	GSE19898	25052783	25053003	220	344
p130	Senescent	GSE19898	25053341	25053933	592	1088
p130	shRbQuiescent	GSE19898	25053161	25054112	951	1087
p130	shRbSenescent	GSE19898	25052850	25053978	1128	865

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
CBP	T0-glioblastoma	GSE21026	24909823	24910097	274	2591
Gata1	K562	GSE18868	24898118	24898812	694	14086
Gata2	K562	GSE18868	24898177	24899104	927	13910
Nanog	hES	GSE18292	24908878	24909284	406	3470
Oct1	Hela	GSE14283	24911636	24911668	32	899
Oct1	Hela	GSE14283	24911981	24912012	31	554
Rb	shRbSenescence	GSE19898	24903327	24903534	207	9120

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length
CTCF	CD4	GSE12889	24946727	24946986	259
CTCF	CD4	GSE12889	24971885	24972195	310
CTCF	CD4	SISSRdata	24946727	24946986	259
CTCF	CD4	SISSRdata	24971885	24972195	310
CTCF	Jurkat	GSE12889	24946658	24946980	322
H3K4me3	colorectal	cancer	25050120	25051468	1348
H3ac	HepG2	E	25045405	25047396	1991
H3ac	HepG2	E	25049008	25051636	2628
Myc	K562	GSE19551	24946737	24947095	358
Myc	K562	GSE19551	25010580	25011016	436
Nanog	hES	GSE18292	24971935	24972124	189
Oct1	Hela	GSE14283	24913345	24913395	50
Oct1	Hela	GSE14283	25004414	25004450	36
Oct1	Hela	GSE14283	25005144	25005179	35
Oct1	Hela	GSE14283	25016970	25016999	29
Oct1	Hela	GSE14283	25047103	25047140	37
RARA	MCF7	GSE15244	24948560	24949321	761
RARA	MCF7	GSE15244	25050955	25051431	476
RARG	MCF7	GSE15244	24947375	24947940	565
RARG	MCF7	GSE15244	24948560	24949288	728
RARG	MCF7	GSE15244	25046982	25047396	414
RARG	MCF7	GSE15244	25050883	25051407	524
Rb	Quiescent	GSE19898	25050581	25050734	153
Rb	shRbSenescence	GSE19898	24979598	24979866	268
TAF	k562	GSE8489	25009670	25011105	1435
TAF	k562	GSE8489	25048796	25051504	2708
TFAP2C	MCF7	GSE21234	24948695	24949315	620
hScc1	Bcell	GSE12603	24971491	24972578	1087
hScc1	Bcell	GSE12603	25030559	25030959	400
hScc1	Bcell	GSE12603	25051611	25052510	899
hScc1	CdLS	GSE12603	24971697	24972725	1028

Validated miRNA targets

Cis-Nats regulation

Simple Query:

Paper Collected: 6/30/2018

Last Update: 8/26/2018