AutismKB 2.0

Annotation Detail for ISLR2


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:ISLR2 ( KIAA1465 )
Gene Full Name: immunoglobulin superfamily containing leucine-rich repeat 2
Band: 15q24.1
Quick LinksEntrez ID:57611; OMIM: NA; Uniprot ID:ISLR2_HUMAN; ENSEMBL ID: ENSG00000167178; HGNC ID: 29286
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
52N-linked (GlcNAc...) (Potential).
121N-linked (GlcNAc...) (Potential).
337N-linked (GlcNAc...) (Potential).
364N-linked (GlcNAc...) (Potential).
474N-linked (GlcNAc...) (Potential).
563N-linked (GlcNAc...) (Potential).
Location(AA) Modifications Resource
No data
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_020851
  • Location:chr15 72209997-72216193
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 72206879 72207324 445 2896
CTCF CD4SISSRdata 72206879 72207324 445 2896
CTCF G2GSE9613 72206607 72207313 706 3038
KLF4 hESGSE17917 72208005 72208392 387 1799
hScc1 BcellGSE12603 72206607 72208532 1925 2428
hScc1 CdLSGSE12603 72206497 72207519 1022 2990
hScc1 G2GSE9613 72206607 72207353 746 3018
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
NRSF JurkatGSE13047 72225674 72225964 290 9626
NRSF-mono JurkatQuESTdata 72225673 72225957 284 9622
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 72211837 72212200 363 0
CTCF G2GSE9613 72212571 72213145 574 0
CTCF G2GSE9613 72213589 72214294 705 0
CTCF G2GSE9613 72215504 72215916 412 0
H3K27me3 colorectalcancer 72209548 72212200 2652 0
PHF8 HeLaGSE20725 72215031 72216404 1373 0
hScc1 BcellGSE12603 72212278 72213189 911 0
hScc1 BcellGSE12603 72213763 72214175 412 0
hScc1 BcellGSE12603 72215504 72216574 1070 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
9056 mRNA KIAA1465 chr15 72209997 72216196 147 EST chr15 72211960 72212287Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018