AutismKB 2.0

Annotation Detail for PHRF1


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Basic Information Top
Gene Symbol:PHRF1 ( KIAA1542,RNF221 )
Gene Full Name: PHD and ring finger domains 1
Band: 11p15.5
Quick LinksEntrez ID:57661; OMIM: 611780; Uniprot ID:PHRF1_HUMAN; ENSEMBL ID: ENSG00000070047; HGNC ID: 24351
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
330Phosphothreonine.
846Phosphoserine.
864Phosphoserine.
867Phosphoserine.
915Phosphoserine.
917Phosphothreonine.
925Phosphoserine.
936Phosphoserine.
973Phosphoserine.
991Phosphoserine.
1032Phosphoserine (By similarity).
1034Phosphoserine (By similarity).
1093Phosphoserine.
1095Phosphoserine.
1124Phosphoserine.
1127Phosphoserine.
1128Phosphoserine.
1202Phosphoserine.
1359Phosphoserine.
1360Phosphoserine.
1371Phosphoserine.
1389Phosphoserine.
1404Phosphothreonine.
Location(AA) Modifications Resource
No data
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_020901
  • Location:chr11 566485-602219
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ETS1 JurkatGSE17954 565960 566986 1026 13
H3ac HepG2E 564859 565350 491 1381
NFkBII GM15510GSE19485 565683 566935 1252 177
NFkBII GM18505GSE19485 565870 566987 1117 57
NRSF pAbJurkat 565585 566080 495 653
Rb GrowingGSE19898 566279 566530 251 81
Rb QuiescentGSE19898 566078 566632 554 131
Rb SenescentGSE19898 565796 566019 223 578
Rb SenescentGSE19898 566123 566537 414 156
Rb shRbQuiescentGSE19898 566155 566472 317 172
Rb shRbSenescenceGSE19898 566224 566504 280 122
USF1 HepG2E 564615 565385 770 1486
hScc1 BcellGSE12603 565149 565821 672 1001
p130 QuiescentGSE19898 566105 566629 524 119
p130 SenescentGSE19898 566115 566537 422 160
p130 shRbQuiescentGSE19898 566030 566544 514 199
p130 shRbSenescentGSE19898 566097 566562 465 156
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
TFAP2C MCF7GSE21234 602191 602563 372 158
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
FOXA1 MCF7GSE15244 575156 575640 484 0
Fos K562GSE19551 577733 578355 622 0
GABP HelaGSE8489 575120 575640 520 0
GABP HelaGSE8489 579612 580191 579 0
H3ac HepG2E 567266 568567 1301 0
H3ac HepG2E 569589 570305 716 0
H3ac HepG2E 575120 575640 520 0
NRSF pAbJurkat 566786 567293 507 0
NRSF pAbJurkat 568042 568394 352 0
NRSF pAbJurkat 575228 575640 412 0
NRSF pAbJurkat 587785 588179 394 0
NRSF pAbJurkat 589555 589836 281 0
NRSF pAbJurkat 597318 597712 394 0
NRSF pAbJurkat 600149 600731 582 0
NRSF pAbJurkat 601552 601912 360 0
PHF8 Hs68plusFBSGSE20725 566058 567512 1454 0
RARA MCF7GSE15244 575228 575640 412 0
RARG MCF7GSE15244 575120 575640 520 0
hScc1 BcellGSE12603 566978 567266 288 0
hScc1 BcellGSE12603 588257 588583 326 0
hScc1 BcellGSE12603 597933 598556 623 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018