AutismKB 2.0

Annotation Detail for GPAM


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Basic Information Top
Gene Symbol:GPAM ( GPAT,GPAT1,KIAA1560,MGC26846 )
Gene Full Name: glycerol-3-phosphate acyltransferase, mitochondrial
Band: 10q25.2
Quick LinksEntrez ID:57678; OMIM: 602395; Uniprot ID:GPAT1_HUMAN; ENSEMBL ID: ENSG00000119927; HGNC ID: 24865
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
111Phosphotyrosine.
235HXXXXD motif.
695Phosphoserine.
Location(AA) Modifications Resource
No data
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_020918
  • Location:chr10 113899611-113933507
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ETS1 JurkatGSE17954 113933044 113934069 1025 49
Fos K562GSE19551 113952429 113952722 293 19068
Myc K562GSE19551 113933268 113933861 593 57
Myc hESGSE17917 113933448 113933783 335 108
NRSF JurkatSISSRdata 113933416 113933736 320 69
Oct1 H2O2-HelaGSE14283 113946420 113946453 33 12929
Oct1 HelaGSE14283 113946421 113946457 36 12932
Rb SenescentGSE19898 113933380 113933651 271 8
p130 SenescentGSE19898 113933298 113933986 688 135
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 113887246 113887520 274 12229
CTCF CD4GSE12889 113890003 113890228 225 9496
CTCF CD4SISSRdata 113887246 113887520 274 12229
CTCF CD4SISSRdata 113890003 113890228 225 9496
Oct1 HelaGSE14283 113896210 113896265 55 3374
RARG MCF7GSE15244 113890093 113890862 769 9134
Rb QuiescentGSE19898 113887169 113887339 170 12358
STAT1 HeLaGSE12783 113883696 113885240 1544 15144
hScc1 BcellGSE12603 113886802 113887529 727 12446
hScc1 BcellGSE12603 113888975 113889144 169 10552
hScc1 BcellGSE12603 113889749 113890130 381 9672
hScc1 CdLSGSE12603 113886949 113887529 580 12373
hScc1 G2GSE9613 113886873 113887572 699 12389
hScc1 G2GSE9613 113889791 113890459 668 9487
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Oct1 H2O2-HelaGSE14283 113920905 113920935 30 0
PHF8 293TGSE20725 113932790 113934192 1402 0
PHF8 HeLaGSE20725 113932931 113933955 1024 0
Rb QuiescentGSE19898 113933343 113933641 298 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-let-7b hsa-let-7b 22 18668040
hsa-let-7b* hsa-let-7b 22 18668040
hsa-miR-1 hsa-mir-1-2 18 18668040
hsa-miR-1 hsa-mir-1-1 20 18668040
hsa-miR-155 hsa-mir-155 21 18668040
hsa-miR-155* hsa-mir-155 21 18668040
hsa-miR-16 hsa-mir-16-1 13 18668040
hsa-miR-16 hsa-mir-16-2 3 18668040
hsa-miR-30a hsa-mir-30a 6 18668040
hsa-miR-30a* hsa-mir-30a 6 18668040
hsa-miR-30b hsa-mir-30b 8 18668040
hsa-miR-30b* hsa-mir-30b 8 18668040
hsa-miR-30c hsa-mir-30c-2 6 18668040
hsa-miR-30c hsa-mir-30c-1 1 18668040
hsa-miR-30c-1* hsa-mir-30c-1 1 18668040
hsa-miR-30c-2* hsa-mir-30c-2 6 18668040
hsa-miR-30d hsa-mir-30d 8 18668040
hsa-miR-30d* hsa-mir-30d 8 18668040
hsa-miR-30e hsa-mir-30e 1 18668040
hsa-miR-30e* hsa-mir-30e 1 18668040
ID in Tarbase Data Type Support Type miRNA Gene Direct Support Publication
1046 Unknown pSILAC miR-16 GPAM down 50-25% 18668040
Ensembl Protein Type Differentially expressed in Pathology or Event Mis Regulation Gene Expression Tumour Involvement
ENSG00000119927 n_a n_a n_a "lymphocyte, muscle cell" "benign tumour, malignant tumour, carcinoma, leukaemia, sarcoma"
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018