Annotation Detail for KIAA1598

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Basic Information Top

Gene Symbol:	KIAA1598 ( DKFZp686A0439,MGC40476,SHOOTIN1,shootin-1 )
Gene Full Name:	KIAA1598
Band:	10q25.3
Quick Links	Entrez ID:57698; OMIM: 611171; Uniprot ID:SHOT1_HUMAN; ENSEMBL ID: ENSG00000187164; HGNC ID:
Relate to Another Database:	SFARIGene; denovo-db

Post Translation Modification

Location(AA)	Modification
3	Phosphoserine (By similarity).
4	Phosphoserine (By similarity).
464	Phosphoserine (By similarity).
467	Phosphoserine (By similarity).
494	Phosphoserine.
496	Phosphothreonine.
506	Phosphoserine.
515	Phosphoserine.
532	Phosphoserine.
537	Phosphothreonine.

Validated transcription factor binding site by ChIP-Chip and ChIP-Seq

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
ER	MCF7	GSE19013	118754796	118755933	1137	499
Fos	K562	GSE19551	118756447	118756976	529	1846
p130	shRbQuiescent	GSE19898	118754667	118755115	448	26

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
Nanog	hES	GSE18292	118629359	118629956	597	4640

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length
CBP	T0-glioblastoma	GSE21026	118712373	118712590	217
CBP	T30-glioblastoma	GSE21026	118712103	118712594	491
Fos	K562	GSE19551	118696486	118697121	635
H3ac	HepG2	E	118753697	118754511	814
Nanog	hES	GSE18292	118667538	118667853	315
Oct1	H2O2-Hela	GSE14283	118717099	118717134	35
Oct1	H2O2-Hela	GSE14283	118737492	118737525	33
Oct1	H2O2-Hela	GSE14283	118754226	118754260	34
Oct1	Hela	GSE14283	118717098	118717133	35
Oct4	hES	GSE21916	118741655	118742054	399
P300	T30-glioblastoma	GSE21026	118637895	118638806	911
P300	T30-glioblastoma	GSE21026	118696446	118697678	1232
PHF8	HeLa	GSE20725	118753829	118755423	1594
RARA	MCF7	GSE15244	118752573	118752939	366
RNAII	Tamoxifen-MCF7	GSE14664	118717098	118717134	36
Rb	Senescent	GSE19898	118754471	118754805	334
Stat6	IL-4-hr1	GSE17850	118725567	118726059	492
TFAP2C	MCF7	GSE21234	118739801	118740202	401
TFAP2C	MCF7	GSE21234	118753861	118754823	962
hScc1	Bcell	GSE12603	118754079	118754797	718
p130	Quiescent	GSE19898	118754092	118754288	196
p130	Senescent	GSE19898	118754392	118754849	457
p130	shRbQuiescent	GSE19898	118754075	118754531	456
p130	shRbSenescent	GSE19898	118754054	118754445	391

Validated miRNA targets

Micro RNA Name	Stem Loop Name	The chromosome that miRNA located	Publication
hsa-miR-1	hsa-mir-1-2	18	15685193
hsa-miR-1	hsa-mir-1-1	20	15685193
hsa-miR-124	hsa-mir-124-1	8	15685193
hsa-miR-124	hsa-mir-124-2	8	15685193
hsa-miR-124	hsa-mir-124-3	20	15685193
hsa-miR-373	hsa-mir-373	19	15685193
hsa-miR-373*	hsa-mir-373	19	15685193

ID in Tarbase	Data Type	Support Type	miRNA	Gene	Direct Support	Publication
158	Unknown	MicroArray	miR-1	KIAA1598	n_a	15685193
Ensembl	Protein Type	Differentially expressed in	Pathology or Event	Mis Regulation	Gene Expression	Tumour Involvement
ENSG00000187164		"cardiac and skeletal muscles, cardiogenesis"	n_a	n_a	"leukocyte, macrophage, muscle cell"	"benign tumour, malignant tumour, carcinoma, leukaemia, sarcoma"

Cis-Nats regulation

Simple Query:

Paper Collected: 6/30/2018

Last Update: 8/26/2018