AutismKB 2.0

Annotation Detail for PTPN13


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Basic Information Top
Gene Symbol:PTPN13 ( DKFZp686J1497,FAP-1,PNP1,PTP-BAS,PTP-BL,PTP1E,PTPL1,PTPLE )
Gene Full Name: protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
Band: 4q21.3
Quick LinksEntrez ID:5783; OMIM: 600267; Uniprot ID:PTN13_HUMAN; ENSEMBL ID: ENSG00000163629; HGNC ID: 9646
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
908Phosphoserine.
911Phosphoserine.
1321Phosphoserine (By similarity).
1629Phosphoserine.
Location(AA) Modifications Resource
Location(AA) Modification Resource
26N-linkedHMM predict
31Phosphoserine(CK1)HMM predict
40Phosphoserine(PKG)HMM predict
40Phosphoserine(IKK)HMM predict
65Phosphoserine(CK2)HMM predict
70N-linkedHMM predict
73N-linkedHMM predict
87N-linkedHMM predict
92Phosphoserine(CK1)HMM predict
119Phosphoserine(ATM)HMM predict
119Phosphoserine(IKK)HMM predict
179N-linkedHMM predict
211Phosphothreonine(PKC)HMM predict
249Phosphothreonine(CK2)HMM predict
263Phosphoserine(CK2)HMM predict
314Phosphoserine(CK1)HMM predict
330Phosphothreonine(PKC)HMM predict
334Phosphoserine(PKG)HMM predict
335Phosphothreonine(PKC)HMM predict
336Phosphothreonine(CDC2)HMM predict
336Phosphothreonine(MAPK)HMM predict
371O-linkedHMM predict
371O-linkedHMM predict
415Phosphoserine(CK2)HMM predict
418Phosphoserine(ATM)HMM predict
420Phosphoserine(CK1)HMM predict
423Phosphoserine(CK2)HMM predict
454Phosphoserine(CK1)HMM predict
454Phosphoserine(ATM)HMM predict
458Phosphoserine(ATM)HMM predict
465Phosphotyrosine(Syk)HMM predict
531Phosphothreonine(PKC)HMM predict
648Phosphothreonine(PKA)HMM predict
653N-linkedHMM predict
699Phosphoserine(CK1)HMM predict
711SulfotyrosineHMM predict
714SulfotyrosineHMM predict
876Phosphoserine(PKG)HMM predict
911Phosphoserine(IKK)HMM predict
926Phosphoserine(CK2)HMM predict
948N-linkedHMM predict
954N-linkedHMM predict
958PhosphoserineHMM predict
995Phosphothreonine(PKC)HMM predict
1010Phosphoserine(ATM)HMM predict
1031N-linkedHMM predict
1033Phosphoserine(CDC2)HMM predict
1033Phosphoserine(CDK)HMM predict
1043Phosphoserine(CK1)HMM predict
1044Phosphoserine(CK1)HMM predict
1045Phosphoserine(CK1)HMM predict
1045Phosphoserine(IKK)HMM predict
1062Phosphoserine(ATM)HMM predict
1064N-linkedHMM predict
1067Phosphoserine(ATM)HMM predict
1086Phosphoserine(CDC2)HMM predict
1176Phosphoserine(ATM)HMM predict
1188Phosphothreonine(MAPK)HMM predict
1188Phosphothreonine(CDK)HMM predict
1199Phosphotyrosine(INSR)HMM predict
1224Phosphothreonine(PKC)HMM predict
1243Phosphoserine(CK1)HMM predict
1243Phosphoserine(IKK)HMM predict
1246Phosphoserine(ATM)HMM predict
1249Phosphoserine(IKK)HMM predict
1253Phosphoserine(IKK)HMM predict
1255Phosphoserine(IKK)HMM predict
1257Phosphoserine(CK1)HMM predict
1257Phosphoserine(ATM)HMM predict
1257Phosphoserine(IKK)HMM predict
1259Phosphoserine(ATM)HMM predict
1281O-linkedHMM predict
1281Phosphoserine(CDC2)HMM predict
1281Phosphoserine(ATM)HMM predict
1281Phosphoserine(IKK)HMM predict
1281PhosphoserineHMM predict
1283Phosphoserine(CDC2)HMM predict
1283Phosphoserine(ATM)HMM predict
1299O-linkedHMM predict
1300N-linkedHMM predict
1331Phosphoserine(ATM)HMM predict
1336Phosphothreonine(CDC2)HMM predict
1336Phosphothreonine(MAPK)HMM predict
1342O-linkedHMM predict
1343Phosphoserine(CK1)HMM predict
1344Phosphoserine(CK1)HMM predict
1344Phosphoserine(ATM)HMM predict
1344Phosphoserine(IKK)HMM predict
1359Phosphoserine(CDC2)HMM predict
1359Phosphoserine(CDK)HMM predict
1359Phosphoserine(ATM)HMM predict
1396Phosphotyrosine(EGFR)HMM predict
1454Phosphoserine(CDC2)HMM predict
1457Phosphoserine(CK1)HMM predict
1464Phosphothreonine(MAPK)HMM predict
1486Phosphothreonine(PKA)HMM predict
1507N-linkedHMM predict
1602Phosphothreonine(MAPK)HMM predict
1602Phosphothreonine(CDK)HMM predict
1613N-linkedHMM predict
1619Phosphoserine(ATM)HMM predict
1619Phosphoserine(IKK)HMM predict
1622Phosphoserine(IKK)HMM predict
1628Phosphothreonine(CK2)HMM predict
1629Phosphoserine(CK1)HMM predict
1629Phosphoserine(CK2)HMM predict
1629Phosphoserine(IKK)HMM predict
1630Phosphoserine(CK1)HMM predict
1630Phosphoserine(CK2)HMM predict
1636Phosphoserine(CK1)HMM predict
1636Phosphoserine(CK2)HMM predict
1645Phosphoserine(CDC2)HMM predict
1647PhosphoserineHMM predict
1651Phosphoserine(PKA)HMM predict
1651Phosphoserine(PKG)HMM predict
1651Phosphoserine(CAMK2)HMM predict
1651Phosphoserine(IKK)HMM predict
1651Phosphoserine(PKB)HMM predict
1651PhosphoserineHMM predict
1653Phosphoserine(CK1)HMM predict
1658Phosphoserine(CK1)HMM predict
1658Phosphoserine(CK2)HMM predict
1669N-linkedHMM predict
1672N-linkedHMM predict
1688Phosphoserine(ATM)HMM predict
1699Phosphoserine(ATM)HMM predict
1699Phosphoserine(IKK)HMM predict
1724N-linkedHMM predict
1726O-linkedHMM predict
1726Phosphoserine(CDC2)HMM predict
1726Phosphoserine(CDK)HMM predict
1744Phosphoserine(IKK)HMM predict
1746Phosphoserine(IKK)HMM predict
1747Phosphoserine(CK1)HMM predict
1766N-linkedHMM predict
1772N-linkedHMM predict
1838N-linkedHMM predict
1844N-linkedHMM predict
1860Phosphothreonine(PKC)HMM predict
1973O-linkedHMM predict
1983Phosphoserine(IKK)HMM predict
1987N-linkedHMM predict
1996O-linkedHMM predict
1996Phosphoserine(ATM)HMM predict
2001Phosphothreonine(MAPK)HMM predict
2003N-linkedHMM predict
2034N-linkedHMM predict
2049Phosphotyrosine(EGFR)HMM predict
2049Phosphotyrosine(INSR)HMM predict
2049Phosphotyrosine(Syk)HMM predict
2049SulfotyrosineHMM predict
2052Phosphoserine(ATM)HMM predict
2081Phosphotyrosine(Jak)HMM predict
2144Phosphothreonine(CK2)HMM predict
2166Phosphoserine(CK1)HMM predict
2262Phosphotyrosine(INSR)HMM predict
2264N-linkedHMM predict
2279Phosphotyrosine(Jak)HMM predict
2356Phosphothreonine(PKC)HMM predict
2372N-linkedHMM predict
2381Phosphothreonine(CDC2)HMM predict
2381Phosphothreonine(CDK)HMM predict
2383Phosphoserine(ATM)HMM predict
2429Phosphoserine(ATM)HMM predict
2453Phosphothreonine(CK2)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_006264
  • Location:chr4 87734908-87955325
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 87734306 87734832 526 340
TFAP2C MCF7GSE21234 87733854 87734590 736 687
hScc1 BcellGSE12603 87734267 87734768 501 391
hScc1 G2GSE9613 87734228 87735253 1025 168
p63 keratinocytesGSE17611 87725967 87726912 945 8469
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 87911462 87911637 175 0
ER Fulvestrant-MCF7GSE14664 87948641 87948731 90 0
H3K27me3 colorectalcancer 87735022 87736566 1544 0
NFkBII GM12878GSE19485 87797643 87799105 1462 0
Nanog hESGSE18292 87914972 87915319 347 0
Oct1 H2O2-HelaGSE14283 87752375 87752449 74 0
Oct1 H2O2-HelaGSE14283 87829289 87829323 34 0
Oct1 H2O2-HelaGSE14283 87839443 87839478 35 0
Oct1 H2O2-HelaGSE14283 87948647 87948680 33 0
Oct1 HelaGSE14283 87752390 87752430 40 0
Oct1 HelaGSE14283 87779700 87779741 41 0
Oct1 HelaGSE14283 87829289 87829327 38 0
Oct1 HelaGSE14283 87839442 87839490 48 0
Oct1 HelaGSE14283 87845537 87845565 28 0
Oct1 HelaGSE14283 87845872 87845901 29 0
Oct1 HelaGSE14283 87887264 87887302 38 0
Oct1 HelaGSE14283 87939001 87939030 29 0
Oct1 HelaGSE14283 87948637 87948728 91 0
RNAII Tamoxifen-MCF7GSE14664 87845534 87845571 37 0
p130 QuiescentGSE19898 87735182 87735602 420 0
p63 keratinocytesGSE17611 87897455 87898012 557 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-141 hsa-mir-141 12 20420713
hsa-miR-141* hsa-mir-141 12 20420713
hsa-miR-142-3p hsa-mir-142 17 20420713
hsa-miR-149 hsa-mir-149 2 20420713
hsa-miR-149* hsa-mir-149 2 20420713
hsa-miR-185 hsa-mir-185 22 20420713
hsa-miR-185* hsa-mir-185 22 20420713
hsa-miR-200a* hsa-mir-200a 1 20420713
hsa-miR-200c hsa-mir-200c 12 20420713
hsa-miR-200c hsa-mir-200c 12 20620960
hsa-miR-200c* hsa-mir-200c 12 20420713
hsa-miR-200c* hsa-mir-200c 12 20620960
hsa-miR-21 hsa-mir-21 17 20420713
hsa-miR-21* hsa-mir-21 17 20420713
hsa-miR-224 hsa-mir-224 X 20420713
hsa-miR-34a hsa-mir-34a 1 20420713
hsa-miR-34a* hsa-mir-34a 1 20420713
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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