AutismKB 2.0

Annotation Detail for PTPN14


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Basic Information Top
Gene Symbol:PTPN14 ( MGC126803,PEZ,PTP36 )
Gene Full Name: protein tyrosine phosphatase, non-receptor type 14
Band: 1q32.3-q41
Quick LinksEntrez ID:5784; OMIM: 603155; Uniprot ID:PTN14_HUMAN; ENSEMBL ID: ENSG00000152104; HGNC ID: 9647
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
486Phosphoserine.
512Phosphoserine.
584Phosphoserine.
593Phosphoserine.
594Phosphoserine.
Location(AA) Modifications Resource
584Phosphoserine.Swiss-Prot 53.0
584PhosphoserinePhospho.ELM 6.0
593Phosphoserine (By similarity).Swiss-Prot 53.0
594Phosphoserine (By similarity).Swiss-Prot 53.0
Location(AA) Modification Resource
70Phosphoserine(ATM)HMM predict
153SulfotyrosineHMM predict
259N-linkedHMM predict
263N-linkedHMM predict
314Phosphoserine(CDC2)HMM predict
314Phosphoserine(ATM)HMM predict
354Phosphoserine(ATM)HMM predict
380N-linkedHMM predict
385N-linkedHMM predict
393O-linkedHMM predict
398N-linkedHMM predict
400Phosphoserine(ATM)HMM predict
412N-linkedHMM predict
414Phosphoserine(CK1)HMM predict
445Phosphotyrosine(Syk)HMM predict
461Phosphoserine(ATM)HMM predict
461Phosphoserine(CAMK2)HMM predict
461Phosphoserine(IKK)HMM predict
477Phosphotyrosine(Abl)HMM predict
485Phosphotyrosine(SRC)HMM predict
485Phosphotyrosine(Abl)HMM predict
486Phosphoserine(ATM)HMM predict
496Phosphotyrosine(Syk)HMM predict
496Phosphotyrosine(INSR)HMM predict
531O-linkedHMM predict
534O-linkedHMM predict
534O-linkedHMM predict
536O-linkedHMM predict
539Phosphothreonine(CDK)HMM predict
553Phosphotyrosine(INSR)HMM predict
553Phosphotyrosine(Abl)HMM predict
578O-linkedHMM predict
579Phosphothreonine(CDK)HMM predict
614Phosphoserine(ATM)HMM predict
657Phosphothreonine(PKC)HMM predict
670Phosphothreonine(PKC)HMM predict
670Phosphothreonine(PKA)HMM predict
681Phosphoserine(CK1)HMM predict
708Phosphoserine(CK2)HMM predict
710Phosphoserine(CK2)HMM predict
710Phosphoserine(CK1)HMM predict
720Phosphoserine(ATM)HMM predict
835Phosphoserine(CK1)HMM predict
899Phosphothreonine(PKC)HMM predict
913Phosphotyrosine(EGFR)HMM predict
958N-linkedHMM predict
959N-linkedHMM predict
962Phosphotyrosine(INSR)HMM predict
964N-linkedHMM predict
1017Phosphothreonine(PKC)HMM predict
1103Phosphothreonine(PKA)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_005401
  • Location:chr1 212597633-212791264
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 212790937 212792251 1314 330
H3ac HepG2E 212792287 212792765 478 1262
p130 shRbQuiescentGSE19898 212791893 212792524 631 944
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 212745223 212745370 147 0
CTCF G2GSE9613 212772262 212773467 1205 0
FoxA1 MCF7MACSdata 212707273 212707422 149 0
H3ac HepG2E 212678967 212679970 1003 0
H3ac HepG2E 212789484 212790756 1272 0
KLF4 hESGSE17917 212679720 212679891 171 0
KLF4 hESGSE17917 212704784 212705148 364 0
Myc K562GSE19551 212659637 212659965 328 0
Nanog hESGSE18292 212753988 212754246 258 0
Oct4 hESGSE17917 212704992 212705147 155 0
P300 T0-glioblastomaGSE21026 212617540 212618686 1146 0
P300 T30-glioblastomaGSE21026 212617520 212618896 1376 0
P300 T30-glioblastomaGSE21026 212643915 212644619 704 0
P300 T30-glioblastomaGSE21026 212764927 212766304 1377 0
RARA MCF7GSE15244 212679352 212679970 618 0
RARA MCF7GSE15244 212772400 212773229 829 0
TFAP2C MCF7GSE21234 212679364 212679921 557 0
TFAP2C MCF7GSE21234 212706702 212707118 416 0
hScc1 BcellGSE12603 212772262 212773467 1205 0
p130 QuiescentGSE19898 212685839 212686093 254 0
p130 QuiescentGSE19898 212687076 212687267 191 0
p130 SenescentGSE19898 212667713 212668161 448 0
p130 SenescentGSE19898 212686947 212687308 361 0
p130 SenescentGSE19898 212695095 212695433 338 0
p130 shRbSenescentGSE19898 212667789 212668057 268 0
p63 keratinocytesGSE17611 212660177 212660924 747 0
p63 keratinocytesGSE17611 212679204 212680046 842 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-141 hsa-mir-141 12 18376396
hsa-miR-141* hsa-mir-141 12 18376396
hsa-miR-200a hsa-mir-200a 1 18376396
hsa-miR-200a* hsa-mir-200a 1 18376396
hsa-miR-200b hsa-mir-200b 1 18376396
hsa-miR-200b* hsa-mir-200b 1 18376396
hsa-miR-200c hsa-mir-200c 12 18376396
hsa-miR-200c* hsa-mir-200c 12 18376396
hsa-miR-205 hsa-mir-205 1 18376396
hsa-miR-429 hsa-mir-429 1 18376396
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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