AutismKB 2.0

Annotation Detail for PTPRZ1


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Basic Information Top
Gene Symbol:PTPRZ1 ( HPTPZ,HPTPzeta,PTP-ZETA,PTP18,PTPRZ,PTPZ,RPTPB,RPTPbeta,phosphacan )
Gene Full Name: protein tyrosine phosphatase, receptor-type, Z polypeptide 1
Band: 7q31.32
Quick LinksEntrez ID:5803; OMIM: 176891; Uniprot ID:PTPRZ_HUMAN; ENSEMBL ID: ENSG00000106278; HGNC ID: 9685
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
105N-linked (GlcNAc...).
134N-linked (GlcNAc...) (Potential).
223N-linked (GlcNAc...) (Potential).
232N-linked (GlcNAc...) (Potential).
324N-linked (GlcNAc...) (Potential).
381N-linked (GlcNAc...) (Potential).
497N-linked (GlcNAc...) (Potential).
501N-linked (GlcNAc...) (Potential).
552N-linked (GlcNAc...) (Potential).
587O-linked (Xyl...) (chondroitin sulfate)
602N-linked (GlcNAc...) (Potential).
629N-linked (GlcNAc...) (Potential).
637O-linked (Xyl...) (chondroitin sulfate)
677N-linked (GlcNAc...) (Potential).
997O-linked (Xyl...) (chondroitin sulfate)
1017N-linked (GlcNAc...) (Potential).
1050N-linked (GlcNAc...) (Potential).
1082N-linked (GlcNAc...) (Potential).
1122N-linked (GlcNAc...) (Potential).
1457N-linked (GlcNAc...) (Potential).
1549O-linked (Xyl...) (chondroitin sulfate)
1551O-linked (Xyl...) (chondroitin sulfate)
1562N-linked (GlcNAc...) (Potential).
1618N-linked (GlcNAc...) (Potential).
Location(AA) Modifications Resource
105N-linked (GlcNAc...).Swiss-Prot 53.0
134N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
223N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
232N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
324N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
381N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
497N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
501N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
552N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
587O-linked (Xyl...) (chondroitin sulfate)(Potential).Swiss-Prot 53.0
602N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
629N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
637O-linked (Xyl...) (chondroitin sulfate)(Potential).Swiss-Prot 53.0
677N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
997O-linked (Xyl...) (chondroitin sulfate)(Potential).Swiss-Prot 53.0
1017N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1050N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1082N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1122N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1456N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1548O-linked (Xyl...) (chondroitin sulfate)(Potential).Swiss-Prot 53.0
1550O-linked (Xyl...) (chondroitin sulfate)(Potential).Swiss-Prot 53.0
1561N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1617N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
15S-palmitoylHMM predict
17S-palmitoylHMM predict
58Phosphoserine(CDC2)HMM predict
58Phosphoserine(IKK)HMM predict
105N-linkedHMM predict
108N-linkedHMM predict
134N-linkedHMM predict
140Phosphoserine(CK1)HMM predict
143Phosphoserine(CK1)HMM predict
143Phosphoserine(IKK)HMM predict
223N-linkedHMM predict
232N-linkedHMM predict
237O-linkedHMM predict
254Phosphoserine(IKK)HMM predict
290Phosphotyrosine(SRC)HMM predict
313Phosphoserine(CK1)HMM predict
313Phosphoserine(IKK)HMM predict
324N-linkedHMM predict
325Phosphotyrosine(INSR)HMM predict
368Phosphotyrosine(Syk)HMM predict
449Phosphoserine(PKG)HMM predict
479Phosphothreonine(PKC)HMM predict
480N-linkedHMM predict
482Phosphoserine(CDC2)HMM predict
484Phosphothreonine(PKC)HMM predict
501N-linkedHMM predict
504O-linkedHMM predict
504Phosphoserine(ATM)HMM predict
512Phosphothreonine(PKC)HMM predict
517Phosphoserine(CK1)HMM predict
552N-linkedHMM predict
587O-linkedHMM predict
587O-linkedHMM predict
587Phosphoserine(CK1)HMM predict
587Phosphoserine(ATM)HMM predict
587Phosphoserine(IKK)HMM predict
589O-linkedHMM predict
589O-linkedHMM predict
589Phosphoserine(CK1)HMM predict
590O-linkedHMM predict
590Phosphoserine(CDC2)HMM predict
590Phosphoserine(ATM)HMM predict
590Phosphoserine(IKK)HMM predict
593O-linkedHMM predict
604Phosphoserine(ATM)HMM predict
629N-linkedHMM predict
631Phosphoserine(CAMK2)HMM predict
634Phosphoserine(CK1)HMM predict
636Phosphoserine(CK1)HMM predict
636Phosphoserine(CK2)HMM predict
637Phosphoserine(CK1)HMM predict
656O-linkedHMM predict
658O-linkedHMM predict
677N-linkedHMM predict
700O-linkedHMM predict
724Phosphothreonine(MAPK)HMM predict
729Phosphothreonine(MAPK)HMM predict
729Phosphothreonine(CDK)HMM predict
782N-linkedHMM predict
784O-linkedHMM predict
788O-linkedHMM predict
792O-linkedHMM predict
812Phosphoserine(CK1)HMM predict
881Phosphoserine(CK1)HMM predict
889Phosphothreonine(PKC)HMM predict
906Phosphoserine(ATM)HMM predict
931Phosphoserine(ATM)HMM predict
936Phosphoserine(ATM)HMM predict
964Phosphoserine(ATM)HMM predict
975O-linkedHMM predict
978O-linkedHMM predict
978Phosphothreonine(MAPK)HMM predict
1001Phosphoserine(ATM)HMM predict
1017N-linkedHMM predict
1020Phosphoserine(CDC2)HMM predict
1042Phosphoserine(CK1)HMM predict
1050N-linkedHMM predict
1082N-linkedHMM predict
1089O-linkedHMM predict
1091Phosphoserine(IKK)HMM predict
1094O-linkedHMM predict
1122N-linkedHMM predict
1124O-linkedHMM predict
1130O-linkedHMM predict
1153O-linkedHMM predict
1153Phosphoserine(CK1)HMM predict
1153Phosphoserine(ATM)HMM predict
1157O-linkedHMM predict
1158O-linkedHMM predict
1162Phosphoserine(CDK)HMM predict
1175O-linkedHMM predict
1269Phosphotyrosine(Syk)HMM predict
1278Phosphoserine(CK1)HMM predict
1386Phosphoserine(IKK)HMM predict
1400Phosphoserine(CK1)HMM predict
1421Phosphothreonine(CK2)HMM predict
1433Phosphoserine(CK1)HMM predict
1456N-linkedHMM predict
1477Phosphoserine(CK2)HMM predict
1477Phosphoserine(ATM)HMM predict
1480Phosphoserine(CK1)HMM predict
1480Phosphoserine(CK2)HMM predict
1490Phosphoserine(CK2)HMM predict
1493Phosphoserine(IKK)HMM predict
1500Phosphoserine(ATM)HMM predict
1504Phosphoserine(CDC2)HMM predict
1511Phosphoserine(ATM)HMM predict
1533Phosphoserine(CDC2)HMM predict
1533Phosphoserine(MAPK)HMM predict
1533Phosphoserine(ATM)HMM predict
1543Phosphothreonine(CK2)HMM predict
1548Phosphoserine(CK1)HMM predict
1548Phosphoserine(CK2)HMM predict
1548Phosphoserine(IKK)HMM predict
1561N-linkedHMM predict
1595Phosphoserine(CDC2)HMM predict
1595Phosphoserine(IKK)HMM predict
1597O-linkedHMM predict
1601O-linkedHMM predict
1617N-linkedHMM predict
1618Phosphoserine(CK1)HMM predict
1682O-linkedHMM predict
1686O-linkedHMM predict
1727Phosphotyrosine(Syk)HMM predict
1755Phosphotyrosine(EGFR)HMM predict
1755Phosphotyrosine(INSR)HMM predict
1781Phosphotyrosine(INSR)HMM predict
1868N-linkedHMM predict
1873N-linkedHMM predict
1891Phosphothreonine(PKC)HMM predict
1895SulfotyrosineHMM predict
1981Phosphotyrosine(SRC)HMM predict
2030Phosphoserine(ATM)HMM predict
2051N-linkedHMM predict
2076Phosphotyrosine(INSR)HMM predict
2178Phosphotyrosine(INSR)HMM predict
2195Phosphoserine(CDC2)HMM predict
2289N-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_002851
  • Location:chr7 121300394-121489323
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3K27me3 colorectalcancer 121298246 121298774 528 1885
H3K27me3 colorectalcancer 121299039 121301046 2007 352
Oct1 HelaGSE14283 121293797 121293829 32 6582
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 121421809 121422020 211 0
CTCF G2GSE9613 121422372 121422707 335 0
ER E2-MCF7GSE14664 121449998 121450250 252 0
ER E2-MCF7GSE14664 121461375 121461407 32 0
ER E2-MCF7GSE14664 121468421 121468453 32 0
Oct1 HelaGSE14283 121311188 121311219 31 0
Oct1 HelaGSE14283 121370876 121370913 37 0
Oct1 HelaGSE14283 121449430 121449465 35 0
Oct1 HelaGSE14283 121486303 121486361 58 0
hScc1 BcellGSE12603 121422339 121422668 329 0
hScc1 CdLSGSE12603 121421846 121422751 905 0
hScc1 G2GSE9613 121421809 121422751 942 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
24559 mRNA PTPRZ1 chr7 121107357 121296039 101 EST chr7 121107514 121162217Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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