AutismKB 2.0

Annotation Detail for PTS


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:PTS ( FLJ97081,PTPS )
Gene Full Name: 6-pyruvoyltetrahydropterin synthase
Band: 11q22.3
Quick LinksEntrez ID:5805; OMIM: 612719; Uniprot ID:PTPS_HUMAN; ENSEMBL ID: ENSG00000150787; HGNC ID: 9689
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
19Phosphoserine; by PKG.
Location(AA) Modifications Resource
19Phosphoserine (by PKG).Swiss-Prot 53.0
Location(AA) Modification Resource
19Phosphoserine(PKA)HMM predict
19Phosphoserine(PKG)HMM predict
19Phosphoserine(CAMK2)HMM predict
19Phosphoserine(IKK)HMM predict
19Phosphoserine(PKB)HMM predict
32Phosphoserine(CK2)HMM predict
32Phosphoserine(CK2)HMM predict
79Phosphotyrosine(INSR)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_000317
  • Location:chr11 111602308-111609902
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
p130 SenescentGSE19898 111602049 111602519 470 25
p130 shRbQuiescentGSE19898 111601827 111602470 643 160
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
FOXA1 DLD1GSE12801 111623196 111623559 363 13475
FOXA1 MCF7GSE15244 111617241 111617870 629 7653
FOXA1 MCF7GSE15244 111623123 111623559 436 13439
FOXA1 MCF7GSE15244 111629490 111629745 255 19715
FoxA1 MCF7MACSdata 111617483 111617764 281 7721
GATA3 MCF7GSE15244 111616958 111617870 912 7512
P300 T30-glioblastomaGSE21026 111617255 111618092 837 7771
RARA MCF7GSE15244 111617241 111617870 629 7653
RARG MCF7GSE15244 111617568 111617870 302 7817
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3K4me3 colorectalcancer 111602707 111603335 628 0
H3ac HepG2E 111602707 111603355 648 0
Myc hESGSE17917 111602606 111602922 316 0
PHF8 293TGSE20725 111601898 111603103 1205 0
PHF8 HeLaGSE20725 111601942 111603028 1086 0
PHF8 Hs68minusFBSGSE20725 111601588 111603476 1888 0
PHF8 Hs68plusFBSGSE20725 111601572 111603680 2108 0
Pol2 GM12878GSE19551 111601798 111602929 1131 0
hScc1 CdLSGSE12603 111602186 111602636 450 0
p130 QuiescentGSE19898 111602309 111602492 183 0
p130 SenescentGSE19898 111602918 111603284 366 0
p130 shRbQuiescentGSE19898 111602627 111602994 367 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018