AutismKB 2.0

Annotation Detail for RAP1GDS1


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Basic Information Top
Gene Symbol:RAP1GDS1 ( GDS1,MGC118859,MGC118861,SmgGDS )
Gene Full Name: RAP1, GTP-GDP dissociation stimulator 1
Band: 4q23
Quick LinksEntrez ID:5910; OMIM: 179502; Uniprot ID:GDS1_HUMAN; ENSEMBL ID: ENSG00000138698; HGNC ID: 9859
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
230N6-acetyllysine.
421N6-acetyllysine.
Location(AA) Modifications Resource
Location(AA) Modification Resource
37N-linkedHMM predict
38N-linkedHMM predict
59Phosphothreonine(MAPK)HMM predict
59Phosphothreonine(CDK)HMM predict
92Phosphoserine(MAPK)HMM predict
164N-linkedHMM predict
167N-linkedHMM predict
169N-linkedHMM predict
199Phosphothreonine(PKC)HMM predict
214Phosphoserine(CK1)HMM predict
215Phosphoserine(CK1)HMM predict
280Phosphoserine(CK2)HMM predict
374N-linkedHMM predict
497Phosphothreonine(PKA)HMM predict
547Phosphoserine(CK1)HMM predict
597Phosphoserine(IKK)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_021159
  • Location:chr4 99401642-99582837
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 99400374 99401859 1485 526
ER E2-MCF7GSE14664 99382294 99382342 48 19325
ER Fulvestrant-MCF7GSE14664 99389307 99389354 47 12312
ER Fulvestrant-MCF7GSE14664 99396787 99396822 35 4838
H3K4me3 colorectalcancer 99400008 99400489 481 1394
H3ac HepG2E 99400008 99401108 1100 1085
Oct1 H2O2-HelaGSE14283 99389305 99389351 46 12315
Oct1 H2O2-HelaGSE14283 99400704 99400741 37 920
Oct1 HelaGSE14283 99389300 99389350 50 12318
Oct1 HelaGSE14283 99400703 99400741 38 921
PHF8 293TGSE20725 99400424 99402217 1793 322
PHF8 HeLaGSE20725 99400377 99402495 2118 207
PHF8 Hs68plusFBSGSE20725 99400210 99402619 2409 228
hScc1 BcellGSE12603 99400628 99402294 1666 182
p130 QuiescentGSE19898 99400970 99401416 446 450
p130 SenescentGSE19898 99400878 99401432 554 488
p130 shRbQuiescentGSE19898 99400685 99401445 760 578
p130 shRbSenescentGSE19898 99400928 99401266 338 546
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 99587775 99588115 340 5108
CTCF G2GSE9613 99589054 99589531 477 6455
hScc1 BcellGSE12603 99587932 99588151 219 5204
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3K4me3 colorectalcancer 99402156 99402529 373 0
H3ac HepG2E 99402120 99403131 1011 0
Nanog ESGSE20650 99424761 99425327 566 0
Nanog hESGSE18292 99474757 99475046 289 0
Oct1 H2O2-HelaGSE14283 99430522 99430560 38 0
Oct1 HelaGSE14283 99430522 99430560 38 0
Oct1 HelaGSE14283 99451139 99451165 26 0
Oct1 HelaGSE14283 99456621 99456658 37 0
Oct1 HelaGSE14283 99473600 99473628 28 0
Oct1 HelaGSE14283 99488173 99488210 37 0
Oct1 HelaGSE14283 99527890 99527918 28 0
Oct1 HelaGSE14283 99531558 99531595 37 0
Rb shRbSenescenceGSE19898 99563417 99563592 175 0
p130 QuiescentGSE19898 99402100 99402328 228 0
p130 shRbSenescentGSE19898 99401978 99402478 500 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018