AutismKB 2.0

Annotation Detail for RBBP6


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Basic Information Top
Gene Symbol:RBBP6 ( DKFZp686P0638,DKFZp761B2423,MY038,P2P-R,PACT,RBQ-1,SNAMA )
Gene Full Name: retinoblastoma binding protein 6
Band: 16p12.1
Quick LinksEntrez ID:5930; OMIM: 600938; Uniprot ID:RBBP6_HUMAN; ENSEMBL ID: ENSG00000122257; HGNC ID: 9889
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
7N6-acetyllysine.
244Phosphoserine.
245Phosphoserine.
246Phosphoserine.
247Phosphoserine.
360Phosphoserine.
516Phosphoserine.
730Phosphoserine.
770Phosphoserine.
772Phosphoserine.
861Phosphoserine.
873Phosphoserine.
984Phosphothreonine.
1179Phosphoserine.
1222Phosphothreonine.
1271Phosphothreonine (By similarity).
1277Phosphoserine.
1328Phosphoserine.
1336Phosphothreonine.
1468Phosphothreonine.
1571N6-acetyllysine.
1625Phosphoserine.
1644Phosphoserine.
1646Phosphoserine.
1648Phosphoserine.
1651Phosphoserine.
Location(AA) Modifications Resource
244Phosphoserine.Swiss-Prot 53.0
244PhosphoserinePhospho.ELM 6.0
245Phosphoserine.Swiss-Prot 53.0
245PhosphoserinePhospho.ELM 6.0
246Phosphoserine.Swiss-Prot 53.0
246PhosphoserinePhospho.ELM 6.0
247Phosphoserine.Swiss-Prot 53.0
247PhosphoserinePhospho.ELM 6.0
360Phosphoserine.Swiss-Prot 53.0
360PhosphoserinePhospho.ELM 6.0
363PhosphoserinePhospho.ELM 6.0
516PhosphoserinePhospho.ELM 6.0
516Phosphoserine.Swiss-Prot 53.0
684PhosphoserinePhospho.ELM 6.0
730Phosphoserine.Swiss-Prot 53.0
730PhosphoserinePhospho.ELM 6.0
770PhosphoserinePhospho.ELM 6.0
770Phosphoserine.Swiss-Prot 53.0
772PhosphoserinePhospho.ELM 6.0
772Phosphoserine.Swiss-Prot 53.0
861PhosphoserinePhospho.ELM 6.0
861Phosphoserine.Swiss-Prot 53.0
873Phosphoserine.Swiss-Prot 53.0
873PhosphoserinePhospho.ELM 6.0
1052PhosphoserinePhospho.ELM 6.0
1179PhosphoserinePhospho.ELM 6.0
1179Phosphoserine.Swiss-Prot 53.0
1194PhosphothreoninePhospho.ELM 6.0
1271Phosphothreonine (By similarity).Swiss-Prot 53.0
1277PhosphoserinePhospho.ELM 6.0
1277Phosphoserine.Swiss-Prot 53.0
1328Phosphoserine.Swiss-Prot 53.0
1328PhosphoserinePhospho.ELM 6.0
1468Phosphothreonine.Swiss-Prot 53.0
1468PhosphothreoninePhospho.ELM 6.0
1646PhosphoserinePhospho.ELM 6.0
1648PhosphoserinePhospho.ELM 6.0
1651PhosphoserinePhospho.ELM 6.0
Location(AA) Modification Resource
53Phosphothreonine(PKC)HMM predict
67N-linkedHMM predict
86O-linkedHMM predict
126Phosphoserine(CK2)HMM predict
136Phosphoserine(ATM)HMM predict
142Phosphotyrosine(INSR)HMM predict
244Phosphoserine(CK1)HMM predict
244Phosphoserine(CK2)HMM predict
245Phosphoserine(CK2)HMM predict
246O-linkedHMM predict
246Phosphoserine(CK1)HMM predict
246Phosphoserine(CK2)HMM predict
247Phosphoserine(CK1)HMM predict
275S-palmitoylHMM predict
324N-linkedHMM predict
360Phosphoserine(CDC2)HMM predict
375O-linkedHMM predict
377O-linkedHMM predict
383O-linkedHMM predict
385O-linkedHMM predict
386Phosphoserine(CK1)HMM predict
389O-linkedHMM predict
390N-linkedHMM predict
393O-linkedHMM predict
401N-linkedHMM predict
403O-linkedHMM predict
404O-linkedHMM predict
413O-linkedHMM predict
413O-linkedHMM predict
415O-linkedHMM predict
447Phosphoserine(CK1)HMM predict
464Phosphotyrosine(INSR)HMM predict
464Phosphotyrosine(SRC)HMM predict
464Phosphotyrosine(Syk)HMM predict
471Phosphothreonine(CDK)HMM predict
539Phosphoserine(CAMK2)HMM predict
542Phosphoserine(CK1)HMM predict
549O-linkedHMM predict
584O-linkedHMM predict
584Phosphoserine(CDC2)HMM predict
597Phosphotyrosine(Abl)HMM predict
598O-linkedHMM predict
610N-linkedHMM predict
613O-linkedHMM predict
618O-linkedHMM predict
627O-linkedHMM predict
631O-linkedHMM predict
631O-linkedHMM predict
682Phosphoserine(PKA)HMM predict
682Phosphoserine(PKG)HMM predict
682Phosphoserine(IKK)HMM predict
682PhosphoserineHMM predict
684O-linkedHMM predict
688Phosphoserine(CDC2)HMM predict
688Phosphoserine(IKK)HMM predict
701O-linkedHMM predict
714Phosphoserine(PKA)HMM predict
714Phosphoserine(CAMK2)HMM predict
714Phosphoserine(PKB)HMM predict
714PhosphoserineHMM predict
720Phosphoserine(CK1)HMM predict
728Phosphoserine(IKK)HMM predict
730Phosphoserine(CDK)HMM predict
730Phosphoserine(ATM)HMM predict
736MethylarginineHMM predict
738MethylarginineHMM predict
753Phosphotyrosine(Jak)HMM predict
772Phosphoserine(ATM)HMM predict
772Phosphoserine(PKB)HMM predict
777MethylarginineHMM predict
799Phosphotyrosine(Syk)HMM predict
827Phosphotyrosine(EGFR)HMM predict
838Phosphotyrosine(Syk)HMM predict
842Phosphotyrosine(Syk)HMM predict
859N-linkedHMM predict
873Phosphoserine(CDC2)HMM predict
883Phosphotyrosine(INSR)HMM predict
969N-linkedHMM predict
1052Phosphoserine(PKB)HMM predict
1066Phosphothreonine(MAPK)HMM predict
1078Phosphoserine(CK2)HMM predict
1078Phosphoserine(ATM)HMM predict
1124Phosphothreonine(PKC)HMM predict
1124Phosphothreonine(CK2)HMM predict
1125Phosphothreonine(PKC)HMM predict
1125Phosphothreonine(CK2)HMM predict
1151Phosphothreonine(PKC)HMM predict
1168Phosphoserine(PKG)HMM predict
1179Phosphoserine(CDC2)HMM predict
1194Phosphothreonine(CDK)HMM predict
1224N-linkedHMM predict
1227N-linkedHMM predict
1240Phosphoserine(CK1)HMM predict
1256Phosphothreonine(PKG)HMM predict
1256Phosphothreonine(PKA)HMM predict
1269O-linkedHMM predict
1270O-linkedHMM predict
1274O-linkedHMM predict
1277Phosphoserine(CDC2)HMM predict
1277Phosphoserine(CDK)HMM predict
1328Phosphoserine(CK2)HMM predict
1367Phosphoserine(CK2)HMM predict
1370Phosphoserine(CK1)HMM predict
1395Phosphoserine(PKG)HMM predict
1408Phosphotyrosine(INSR)HMM predict
1421N-linkedHMM predict
1422Phosphoserine(PKA)HMM predict
1422Phosphoserine(PKG)HMM predict
1423Phosphothreonine(PKG)HMM predict
1444Phosphoserine(CK2)HMM predict
1444Phosphoserine(ATM)HMM predict
1463Phosphoserine(PKC)HMM predict
1468Phosphothreonine(CDC2)HMM predict
1477Phosphotyrosine(INSR)HMM predict
1482Phosphotyrosine(Jak)HMM predict
1484Phosphoserine(CDC2)HMM predict
1484Phosphoserine(CDK)HMM predict
1500Phosphoserine(CDC2)HMM predict
1500Phosphoserine(IKK)HMM predict
1524MethyllysineHMM predict
1526Phosphothreonine(PKA)HMM predict
1526Phosphothreonine(PKC)HMM predict
1532Phosphoserine(IKK)HMM predict
1533N-linkedHMM predict
1535Phosphoserine(CDC2)HMM predict
1625Phosphoserine(CK1)HMM predict
1641SulfotyrosineHMM predict
1642N-linkedHMM predict
1644Phosphoserine(CK2)HMM predict
1646Phosphoserine(CK1)HMM predict
1648Phosphoserine(IKK)HMM predict
1651Phosphoserine(CK2)HMM predict
1657Phosphoserine(CK1)HMM predict
1658Phosphoserine(CK1)HMM predict
1658Phosphoserine(ATM)HMM predict
1676Phosphoserine(PKG)HMM predict
1690N-linkedHMM predict
1692Phosphoserine(IKK)HMM predict
1695Phosphoserine(CDC2)HMM predict
1695Phosphoserine(ATM)HMM predict
1697Phosphoserine(ATM)HMM predict
1699Phosphoserine(CDC2)HMM predict
1699Phosphoserine(CDK)HMM predict
1703O-linkedHMM predict
1705Phosphoserine(CAMK2)HMM predict
1705Phosphoserine(CDC2)HMM predict
1705Phosphoserine(IKK)HMM predict
1707Phosphoserine(CK1)HMM predict
1707Phosphoserine(IKK)HMM predict
1709Phosphoserine(CK1)HMM predict
1709Phosphoserine(ATM)HMM predict
1711Phosphothreonine(PKC)HMM predict
1713Phosphoserine(IKK)HMM predict
1715Phosphoserine(IKK)HMM predict
1716O-linkedHMM predict
1719Phosphoserine(IKK)HMM predict
1720Phosphoserine(CK1)HMM predict
1723Phosphoserine(ATM)HMM predict
1760Phosphoserine(ATM)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_006910
  • Location:chr16 24458408-24491681
  • strand:+
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
p130 QuiescentGSE19898 24501454 24501580 126 9836
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
GABP k562GSE8489 24488265 24488999 734 0
NRSF mAbJurkat 24488592 24489106 514 0
Oct1 H2O2-HelaGSE14283 24483199 24483228 29 0
TAF HelaGSE8489 24488195 24489142 947 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-let-7a hsa-let-7a-1 9 20485546
hsa-let-7a hsa-let-7a-2 11 20485546
hsa-let-7a hsa-let-7a-3 22 20485546
hsa-let-7a* hsa-let-7a-1 9 20485546
hsa-let-7a* hsa-let-7a-3 22 20485546
hsa-let-7b hsa-let-7b 22 20485546
hsa-let-7b* hsa-let-7b 22 20485546
hsa-let-7c hsa-let-7c 21 20485546
hsa-let-7c* hsa-let-7c 21 20485546
hsa-let-7d hsa-let-7d 9 20485546
hsa-let-7d* hsa-let-7d 9 20485546
hsa-let-7e hsa-let-7e 19 20485546
hsa-let-7e* hsa-let-7e 19 20485546
hsa-let-7f hsa-let-7f-1 9 20485546
hsa-let-7f hsa-let-7f-2 X 20485546
hsa-let-7f-1* hsa-let-7f-1 9 20485546
hsa-let-7f-2* hsa-let-7f-2 X 20485546
hsa-let-7g hsa-let-7g 3 20485546
hsa-let-7g* hsa-let-7g 3 20485546
hsa-let-7i hsa-let-7i 12 20485546
hsa-let-7i* hsa-let-7i 12 20485546
hsa-miR-107 hsa-mir-107 10 20485546
hsa-miR-134 hsa-mir-134 14 20485546
hsa-miR-143 hsa-mir-143 5 20485546
hsa-miR-143* hsa-mir-143 5 20485546
hsa-miR-145 hsa-mir-145 5 20485546
hsa-miR-145* hsa-mir-145 5 20485546
hsa-miR-16 hsa-mir-16-1 13 20485546
hsa-miR-16 hsa-mir-16-2 3 20485546
hsa-miR-200c hsa-mir-200c 12 20485546
hsa-miR-200c* hsa-mir-200c 12 20485546
hsa-miR-21 hsa-mir-21 17 20485546
hsa-miR-21* hsa-mir-21 17 20485546
hsa-miR-449a hsa-mir-449a 5 20485546
hsa-miR-503 hsa-mir-503 X 20485546
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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