Annotation Detail for BCKDHB

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Basic Information Top

Gene Symbol:	BCKDHB ( E1B,FLJ17880,dJ279A18.1 )
Gene Full Name:	branched chain keto acid dehydrogenase E1, beta polypeptide
Band:	6q14.1
Quick Links	Entrez ID:594; OMIM: 248611; Uniprot ID:ODBB_HUMAN; ENSEMBL ID: ENSG00000083123; HGNC ID: 987
Relate to Another Database:	SFARIGene; denovo-db

Post Translation Modification

Location(AA)	Modification
241	N6-acetyllysine.

Validated transcription factor binding site by ChIP-Chip and ChIP-Seq

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
CTCF	CD4	GSE12889	80860507	80860833	326	12413
CTCF	CD4	SISSRdata	80860507	80860833	326	12413
TFAP2C	MCF7	GSE21234	80872569	80873212	643	192

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
Oct1	H2O2-Hela	GSE14283	81116486	81116527	41	3798
Oct1	H2O2-Hela	GSE14283	81121805	81121845	40	9117
Oct1	Hela	GSE14283	81116487	81116527	40	3799

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length
CTCF	CD4	GSE12889	80899516	80899633	117
CTCF	CD4	GSE12889	80980847	80981224	377
CTCF	CD4	GSE12889	81104747	81104955	208
CTCF	CD4	SISSRdata	80899516	80899633	117
CTCF	CD4	SISSRdata	80980847	80981224	377
CTCF	CD4	SISSRdata	81104747	81104955	208
CTCF	Jurkat	GSE12889	80980960	80981164	204
CTCF	G2	GSE9613	80872889	80873540	651
CTCF	G2	GSE9613	80899534	80899785	251
CTCF	G2	GSE9613	81104662	81105058	396
Fos	K562	GSE19551	80872787	80873377	590
H3ac	HepG2	E	80874166	80874382	216
Myc	K562	GSE19551	80899437	80899742	305
Oct1	H2O2-Hela	GSE14283	81107188	81107228	40
Oct1	H2O2-Hela	GSE14283	81112213	81112239	26
Oct1	Hela	GSE14283	80959649	80959724	75
Oct1	Hela	GSE14283	81107188	81107228	40
Oct1	Hela	GSE14283	81112208	81112240	32
P300	T30-glioblastoma	GSE21026	80894821	80895448	627
PHF8	HeLa	GSE20725	80872574	80873595	1021
RARA	MCF7	GSE15244	80909813	80910287	474
Rb	Growing	GSE19898	80921897	80922076	179
TFAP2C	MCF7	GSE21234	80873278	80873726	448
TFAP2C	MCF7	GSE21234	80889136	80889444	308
hScc1	Bcell	GSE12603	80873326	80873476	150
hScc1	CdLS	GSE12603	80980538	80981251	713
hScc1	CdLS	GSE12603	81104545	81105058	513
hScc1	G2	GSE9613	80899499	80899856	357
hScc1	G2	GSE9613	81104662	81105090	428

Validated miRNA targets

Micro RNA Name	Stem Loop Name	The chromosome that miRNA located	Publication
hsa-let-7b	hsa-let-7b	22	18668040
hsa-let-7b*	hsa-let-7b	22	18668040
hsa-miR-1	hsa-mir-1-2	18	18668040
hsa-miR-1	hsa-mir-1-1	20	18668040
hsa-miR-155	hsa-mir-155	21	18668040
hsa-miR-155*	hsa-mir-155	21	18668040
hsa-miR-16	hsa-mir-16-1	13	18668040
hsa-miR-16	hsa-mir-16-2	3	18668040
hsa-miR-30a	hsa-mir-30a	6	18668040
hsa-miR-30a*	hsa-mir-30a	6	18668040
hsa-miR-30b	hsa-mir-30b	8	18668040
hsa-miR-30b*	hsa-mir-30b	8	18668040
hsa-miR-30c	hsa-mir-30c-2	6	18668040
hsa-miR-30c	hsa-mir-30c-1	1	18668040
hsa-miR-30c-1*	hsa-mir-30c-1	1	18668040
hsa-miR-30c-2*	hsa-mir-30c-2	6	18668040
hsa-miR-30d	hsa-mir-30d	8	18668040
hsa-miR-30d*	hsa-mir-30d	8	18668040
hsa-miR-30e	hsa-mir-30e	1	18668040
hsa-miR-30e*	hsa-mir-30e	1	18668040

ID in Tarbase	Data Type	Support Type	miRNA	Gene	Direct Support	Publication
1139	Unknown	pSILAC	miR-1	BCKDHB	down 50-25%	18668040
Ensembl	Protein Type	Differentially expressed in	Pathology or Event	Mis Regulation	Gene Expression	Tumour Involvement
ENSG00000083123		n_a	n_a	n_a	"epithelium, lymphocyte"	"tumour, malignant tumour, carcinoma, leukaemia, sarcoma"

Cis-Nats regulation

Simple Query:

Paper Collected: 6/30/2018

Last Update: 8/26/2018