AutismKB 2.0

Annotation Detail for DPF2


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Basic Information Top
Gene Symbol:DPF2 ( MGC10180,REQ,UBID4,ubi-d4 )
Gene Full Name: D4, zinc and double PHD fingers family 2
Band: 11q13.1
Quick LinksEntrez ID:5977; OMIM: 601671; Uniprot ID:REQU_HUMAN; ENSEMBL ID: ENSG00000133884; HGNC ID: 9964
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
2N-acetylalanine.
94Phosphoserine.
97Phosphoserine.
142Phosphoserine.
172Phosphotyrosine.
176Phosphothreonine.
200Phosphoserine.
248Phosphothreonine (By similarity).
Location(AA) Modifications Resource
142Phosphoserine.Swiss-Prot 53.0
142PhosphoserinePhospho.ELM 6.0
176Phosphothreonine (By similarity).Swiss-Prot 53.0
Location(AA) Modification Resource
17Phosphotyrosine(Syk)HMM predict
17Phosphotyrosine(EGFR)HMM predict
72Phosphotyrosine(Abl)HMM predict
113Phosphoserine(ATM)HMM predict
172SulfotyrosineHMM predict
172Phosphotyrosine(Syk)HMM predict
176Phosphothreonine(MAPK)HMM predict
176Phosphothreonine(CDC2)HMM predict
195MethyllysineHMM predict
196MethyllysineHMM predict
200Phosphoserine(CK2)HMM predict
244Phosphoserine(ATM)HMM predict
248Phosphothreonine(CDK)HMM predict
248Phosphothreonine(MAPK)HMM predict
248Phosphothreonine(CDC2)HMM predict
319Phosphothreonine(PKC)HMM predict
336Phosphoserine(CK2)HMM predict
362O-linkedHMM predict
374S-palmitoylHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_006268
  • Location:chr11 64857921-64877025
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 64853975 64854253 278 3808
CTCF CD4SISSRdata 64853975 64854253 278 3808
CTCF HelaGSE12889 64854042 64854298 256 3752
GATA3 MCF7GSE15244 64853493 64853896 403 4227
H3ac HepG2E 64853493 64853812 319 4269
HIF1 NormHepG2 64857649 64858031 382 82
Myc K562GSE19551 64853878 64854242 364 3862
Nanog hESGSE18292 64854026 64854247 221 3785
RARA MCF7GSE15244 64853493 64853896 403 4227
Sox2 hESGSE18292 64853923 64854252 329 3834
TFAP2C MCF7GSE21234 64853470 64854003 533 4185
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3K4me2 HCT116GSE10453 64858445 64859805 1360 0
H3K4me3 colorectalcancer 64858232 64858953 721 0
H3ac HepG2E 64857940 64859828 1888 0
Oct1 HelaGSE14283 64862821 64862876 55 0
PHF8 Hs68minusFBSGSE20725 64857649 64858459 810 0
PHF8 Hs68plusFBSGSE20725 64857611 64858674 1063 0
RARG MCF7GSE15244 64867777 64868156 379 0
TAF k562GSE8489 64858372 64859061 689 0
hScc1 CdLSGSE12603 64857720 64858268 548 0
p130 shRbQuiescentGSE19898 64857613 64858353 740 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018