AutismKB 2.0

Annotation Detail for RGS1


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Basic Information Top
Gene Symbol:RGS1 ( 1R20,BL34,IER1,IR20 )
Gene Full Name: regulator of G-protein signaling 1
Band: 1q31.2
Quick LinksEntrez ID:5996; OMIM: 600323; Uniprot ID:RGS1_HUMAN; ENSEMBL ID: ENSG00000090104; HGNC ID: 9991
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
32Phosphoserine; by CK2 (Potential).
67Phosphoserine; by PKC (Potential).
75Phosphoserine; by CK2 (Potential).
159Phosphothreonine; by PKC (Potential).
169Phosphothreonine; by CK2 (Potential).
180Phosphothreonine; by CK2 (Potential).
207Phosphoserine; by PKC (Potential).
Location(AA) Modifications Resource
19Phosphoserine (by CK2) (Potential).Swiss-Prot 53.0
54Phosphoserine (by PKC) (Potential).Swiss-Prot 53.0
62Phosphoserine (by CK2) (Potential).Swiss-Prot 53.0
146Phosphothreonine (by PKC) (Potential).Swiss-Prot 53.0
156Phosphothreonine (by CK2) (Potential).Swiss-Prot 53.0
167Phosphothreonine (by CK2) (Potential).Swiss-Prot 53.0
194Phosphoserine (by PKC) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
55Phosphoserine(PKG)HMM predict
79N-linkedHMM predict
84N-linkedHMM predict
95Phosphoserine(CK1)HMM predict
124Phosphotyrosine(EGFR)HMM predict
154Phosphothreonine(MAPK)HMM predict
174Phosphotyrosine(EGFR)HMM predict
178PhenylalanineHMM predict
179PhenylalanineHMM predict
180PhenylalanineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_002922
  • Location:chr1 190811479-190815781
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Oct1 H2O2-HelaGSE14283 190803504 190803532 28 7962
Oct1 HelaGSE14283 190803715 190803751 36 7747
hScc1 BcellGSE12603 190811270 190811528 258 81
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 190816267 190816491 224 598
CTCF CD4SISSRdata 190816267 190816491 224 598
KLF4 hESGSE17917 190831027 190831237 210 15351
Pol2 GM12878GSE19551 190816026 190817261 1235 862
Stat6 IL-4-hr4GSE17850 190820759 190821269 510 5233
hScc1 BcellGSE12603 190816274 190816742 468 727
hScc1 CdLSGSE12603 190816037 190816742 705 608
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Pol2 GM12878GSE19551 190811292 190811948 656 0
Pol2 GM12878GSE19551 190814779 190815649 870 0
TFAP2C MCF7GSE21234 190814891 190815359 468 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018