AutismKB 2.0

Annotation Detail for BCL6


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Basic Information Top
Gene Symbol:BCL6 ( BCL5,BCL6A,LAZ3,ZBTB27,ZNF51 )
Gene Full Name: B-cell CLL/lymphoma 6
Band: 3q27.3
Quick LinksEntrez ID:604; OMIM: 109565; Uniprot ID:BCL6_HUMAN; ENSEMBL ID: ENSG00000113916; HGNC ID: 1001
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
186Phosphoserine(IKK)HMM predict
189O-linkedHMM predict
190PhosphothreonineHMM predict
190Phosphothreonine(MAPK)HMM predict
209Phosphoserine(ATM)HMM predict
307PhosphoserineHMM predict
307Phosphoserine(CK1)HMM predict
308Phosphoserine(CK2)HMM predict
308Phosphoserine(CK2)HMM predict
308PhosphoserineHMM predict
330Phosphoserine(CDC2)HMM predict
330Phosphoserine(CDK)HMM predict
333Phosphoserine(CDC2)HMM predict
343Phosphoserine(IKK)HMM predict
343Phosphoserine(CDC2)HMM predict
350Phosphoserine(IKK)HMM predict
361Phosphoserine(ATM)HMM predict
366Phosphoserine(CDC2)HMM predict
404Phosphoserine(MAPK)HMM predict
408Phosphotyrosine(Abl)HMM predict
451N-linkedHMM predict
455Phosphothreonine(PKC)HMM predict
457Phosphoserine(CDC2)HMM predict
460Phosphoserine(IKK)HMM predict
461O-linkedHMM predict
461Phosphoserine(CK1)HMM predict
462Phosphoserine(IKK)HMM predict
462Phosphoserine(CK1)HMM predict
466Phosphoserine(IKK)HMM predict
466Phosphoserine(ATM)HMM predict
469PhosphotyrosineHMM predict
477Phosphoserine(IKK)HMM predict
480Phosphoserine(IKK)HMM predict
509Phosphoserine(CK1)HMM predict
532Phosphoserine(CK1)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001706
  • Location:chr3 188921858-188946168
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 188948536 188948758 222 2479
CTCF CD4SISSRdata 188948536 188948758 222 2479
CTCF G2GSE9613 188948019 188949743 1724 2713
CTCF G2GSE9613 188950688 188950814 126 4583
CTCF G2GSE9613 188958077 188958370 293 12055
FOXA1 MCF7GSE15244 188950346 188951450 1104 4730
RARA MCF7GSE15244 188948783 188949106 323 2776
RARA MCF7GSE15244 188950066 188951417 1351 4573
RARG MCF7GSE15244 188950649 188951417 768 4865
STAT1 HeLaGSE12783 188943825 188949174 5349 331
TAF k562GSE8489 188947659 188948344 685 1833
USF1 HepG2E 188949427 188950066 639 3578
USF2 HepG2E 188945682 188947030 1348 188
hScc1 BcellGSE12603 188948419 188948851 432 2467
hScc1 CdLSGSE12603 188948312 188949068 756 2522
hScc1 G2GSE9613 188948157 188949042 885 2431
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 188939146 188943054 3908 0
CTCF G2GSE9613 188943986 188944350 364 0
FOXA1 MCF7GSE15244 188939734 188940799 1065 0
FOXA1 MCF7GSE15244 188945779 188946268 489 0
H3K4me3 colorectalcancer 188938717 188939476 759 0
H3K4me3 colorectalcancer 188940162 188940580 418 0
H3K4me3 colorectalcancer 188941663 188941933 270 0
H3K4me3 colorectalcancer 188944865 188945469 604 0
H3ac HepG2E 188941698 188943592 1894 0
H3ac HepG2E 188943916 188947059 3143 0
RARA MCF7GSE15244 188939734 188940547 813 0
RARG MCF7GSE15244 188939734 188940500 766 0
TAF HelaGSE8489 188944905 188947352 2447 0
TAF k562GSE8489 188943019 188943627 608 0
TAF k562GSE8489 188944459 188947318 2859 0
USF1 HepG2E 188944717 188947139 2422 0
hScc1 BcellGSE12603 188939020 188940044 1024 0
hScc1 BcellGSE12603 188940462 188942983 2521 0
hScc1 CdLSGSE12603 188938937 188943019 4082 0
hScc1 G2GSE9613 188938415 188943592 5177 0
hScc1 G2GSE9613 188943916 188945469 1553 0
p130 shRbQuiescentGSE19898 188940669 188941127 458 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-let-7a hsa-let-7a-1 9 20966935
hsa-let-7a hsa-let-7a-2 11 20966935
hsa-let-7a hsa-let-7a-3 22 20966935
hsa-let-7a hsa-let-7a-1 9 20966935
hsa-let-7a hsa-let-7a-2 11 20966935
hsa-let-7a hsa-let-7a-3 22 20966935
hsa-let-7a* hsa-let-7a-1 9 20966935
hsa-let-7a* hsa-let-7a-3 22 20966935
hsa-let-7a* hsa-let-7a-1 9 20966935
hsa-let-7a* hsa-let-7a-3 22 20966935
hsa-let-7b hsa-let-7b 22 20966935
hsa-let-7b hsa-let-7b 22 20966935
hsa-let-7b* hsa-let-7b 22 20966935
hsa-let-7b* hsa-let-7b 22 20966935
hsa-let-7c hsa-let-7c 21 20966935
hsa-let-7c hsa-let-7c 21 20966935
hsa-let-7c* hsa-let-7c 21 20966935
hsa-let-7c* hsa-let-7c 21 20966935
hsa-let-7d hsa-let-7d 9 20966935
hsa-let-7d hsa-let-7d 9 20966935
hsa-let-7d* hsa-let-7d 9 20966935
hsa-let-7d* hsa-let-7d 9 20966935
hsa-let-7e hsa-let-7e 19 20966935
hsa-let-7e hsa-let-7e 19 20966935
hsa-let-7e* hsa-let-7e 19 20966935
hsa-let-7e* hsa-let-7e 19 20966935
hsa-let-7f hsa-let-7f-1 9 20966935
hsa-let-7f hsa-let-7f-2 X 20966935
hsa-let-7f hsa-let-7f-1 9 20966935
hsa-let-7f hsa-let-7f-2 X 20966935
hsa-let-7f-1* hsa-let-7f-1 9 20966935
hsa-let-7f-1* hsa-let-7f-1 9 20966935
hsa-let-7f-2* hsa-let-7f-2 X 20966935
hsa-let-7f-2* hsa-let-7f-2 X 20966935
hsa-let-7g hsa-let-7g 3 20966935
hsa-let-7g hsa-let-7g 3 20966935
hsa-let-7g* hsa-let-7g 3 20966935
hsa-let-7g* hsa-let-7g 3 20966935
hsa-let-7i hsa-let-7i 12 20966935
hsa-let-7i hsa-let-7i 12 20966935
hsa-let-7i* hsa-let-7i 12 20966935
hsa-let-7i* hsa-let-7i 12 20966935
hsa-miR-127-3p hsa-mir-127 14 18942116
hsa-miR-127-3p hsa-mir-127 14 16766263
hsa-miR-127-3p hsa-mir-127 14 18942116
hsa-miR-127-3p hsa-mir-127 14 16766263
hsa-miR-127-5p hsa-mir-127 14 18942116
hsa-miR-127-5p hsa-mir-127 14 16766263
hsa-miR-127-5p hsa-mir-127 14 18942116
hsa-miR-127-5p hsa-mir-127 14 16766263
hsa-miR-155 hsa-mir-155 21 19956200
hsa-miR-155 hsa-mir-155 21 19956200
hsa-miR-155* hsa-mir-155 21 19956200
hsa-miR-155* hsa-mir-155 21 19956200
hsa-miR-200b hsa-mir-200b 1 18942116
hsa-miR-200b hsa-mir-200b 1 18942116
hsa-miR-200b* hsa-mir-200b 1 18942116
hsa-miR-200b* hsa-mir-200b 1 18942116
hsa-miR-222 hsa-mir-222 X 19956200
hsa-miR-222 hsa-mir-222 X 19956200
hsa-miR-222* hsa-mir-222 X 19956200
hsa-miR-222* hsa-mir-222 X 19956200
hsa-miR-223 hsa-mir-223 X 20802470
hsa-miR-223 hsa-mir-223 X 20802470
hsa-miR-223* hsa-mir-223 X 20802470
hsa-miR-223* hsa-mir-223 X 20802470
hsa-miR-28-3p hsa-mir-28 3 16896311
hsa-miR-28-3p hsa-mir-28 3 16896311
hsa-miR-28-5p hsa-mir-28 3 16896311
hsa-miR-28-5p hsa-mir-28 3 16896311
hsa-miR-30a hsa-mir-30a 6 20966935
hsa-miR-30a hsa-mir-30a 6 20966935
hsa-miR-30a* hsa-mir-30a 6 20966935
hsa-miR-30a* hsa-mir-30a 6 20966935
hsa-miR-30b hsa-mir-30b 8 20966935
hsa-miR-30b hsa-mir-30b 8 20966935
hsa-miR-30b* hsa-mir-30b 8 20966935
hsa-miR-30b* hsa-mir-30b 8 20966935
hsa-miR-30c hsa-mir-30c-2 6 20966935
hsa-miR-30c hsa-mir-30c-1 1 20966935
hsa-miR-30c hsa-mir-30c-2 6 20966935
hsa-miR-30c hsa-mir-30c-1 1 20966935
hsa-miR-30c-1* hsa-mir-30c-1 1 20966935
hsa-miR-30c-1* hsa-mir-30c-1 1 20966935
hsa-miR-30c-2* hsa-mir-30c-2 6 20966935
hsa-miR-30c-2* hsa-mir-30c-2 6 20966935
hsa-miR-30d hsa-mir-30d 8 20966935
hsa-miR-30d hsa-mir-30d 8 20966935
hsa-miR-30d* hsa-mir-30d 8 20966935
hsa-miR-30d* hsa-mir-30d 8 20966935
hsa-miR-30e hsa-mir-30e 1 20966935
hsa-miR-30e hsa-mir-30e 1 20966935
hsa-miR-30e* hsa-mir-30e 1 20966935
hsa-miR-30e* hsa-mir-30e 1 20966935
hsa-miR-34a hsa-mir-34a 1 18942116
hsa-miR-34a hsa-mir-34a 1 18942116
hsa-miR-34a* hsa-mir-34a 1 18942116
hsa-miR-34a* hsa-mir-34a 1 18942116
hsa-miR-424 hsa-mir-424 X 19956200
hsa-miR-424 hsa-mir-424 X 19956200
hsa-miR-424* hsa-mir-424 X 19956200
hsa-miR-424* hsa-mir-424 X 19956200
hsa-miR-503 hsa-mir-503 X 19956200
hsa-miR-503 hsa-mir-503 X 19956200
hsa-miR-9 hsa-mir-9-1 1 20966935
hsa-miR-9 hsa-mir-9-2 5 20966935
hsa-miR-9 hsa-mir-9-3 15 20966935
hsa-miR-9 hsa-mir-9-1 1 19956200
hsa-miR-9 hsa-mir-9-2 5 19956200
hsa-miR-9 hsa-mir-9-3 15 19956200
hsa-miR-9 hsa-mir-9-1 1 20966935
hsa-miR-9 hsa-mir-9-2 5 20966935
hsa-miR-9 hsa-mir-9-3 15 20966935
hsa-miR-9 hsa-mir-9-1 1 19956200
hsa-miR-9 hsa-mir-9-2 5 19956200
hsa-miR-9 hsa-mir-9-3 15 19956200
hsa-miR-9* hsa-mir-9-1 1 20966935
hsa-miR-9* hsa-mir-9-1 1 20966935
ID in Tarbase Data Type Support Type miRNA Gene Direct Support Publication
438 mRNA repression TRUE miR-127 BCL6 in vitro reporter gene assay (Luciferase) 16766263
Ensembl Protein Type Differentially expressed in Pathology or Event Mis Regulation Gene Expression Tumour Involvement
ENSG00000113916 n_a n_a n_a "epithelium, lymphocyte, leukocyte" "benign tumour, malignant tumour, carcinoma, leukaemia, sarcoma"
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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