AutismKB 2.0

Annotation Detail for EXOC4


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Basic Information Top
Gene Symbol:EXOC4 ( MGC27170,REC8,SEC8,SEC8L1,Sec8p )
Gene Full Name: exocyst complex component 4
Band: 7q33
Quick LinksEntrez ID:60412; OMIM: 608185; Uniprot ID:EXOC4_HUMAN; ENSEMBL ID: ENSG00000131558; HGNC ID: 30389
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
2N-acetylalanine.
9N6-acetyllysine.
226Phosphoserine.
233Phosphothreonine.
237Phosphothreonine.
Location(AA) Modifications Resource
237Phosphothreonine.Swiss-Prot 53.0
Location(AA) Modification Resource
13Phosphothreonine(PKC)HMM predict
51Phosphotyrosine(Syk)HMM predict
219Phosphoserine(PKG)HMM predict
237Phosphothreonine(MAPK)HMM predict
274N-linkedHMM predict
315Phosphothreonine(PKA)HMM predict
316Phosphothreonine(PKA)HMM predict
328N-linkedHMM predict
333N-linkedHMM predict
362Phosphotyrosine(Jak)HMM predict
369Phosphothreonine(MAPK)HMM predict
369Phosphothreonine(CDK)HMM predict
410Phosphoserine(PKB)HMM predict
410Phosphoserine(CAMK2)HMM predict
447Phosphoserine(CK2)HMM predict
495N-linkedHMM predict
726Phosphoserine(PKB)HMM predict
738Phosphoserine(ATM)HMM predict
743Phosphoserine(IKK)HMM predict
810Phosphotyrosine(INSR)HMM predict
822Phosphoserine(CK2)HMM predict
829Phosphoserine(CK1)HMM predict
863Phosphoserine(PKG)HMM predict
863Phosphoserine(PKA)HMM predict
880N-linkedHMM predict
883N-linkedHMM predict
899Phosphotyrosine(Syk)HMM predict
899SulfotyrosineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001037126
  • Location:chr7 132588362-132819483
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ETS1 JurkatGSE17954 132587761 132588783 1022 91
Fos K562GSE19551 132587821 132588601 780 152
Nanog ESGSE20650 132588115 132588488 373 61
RARA MCF7GSE15244 132570591 132571513 922 17311
TAFII hESGSE17917 132588054 132588609 555 31
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP JurkatGSE17954 132817892 132820405 2513 0
CTCF G2GSE9613 132724330 132724543 213 0
CTCF G2GSE9613 132769660 132769922 262 0
ER E2-MCF7GSE14664 132684277 132684311 34 0
ER E2-MCF7GSE14664 132788222 132788355 133 0
ER Fulvestrant-MCF7GSE14664 132684421 132684455 34 0
ER Fulvestrant-MCF7GSE14664 132724832 132724867 35 0
FOXA1 MCF7GSE15244 132768507 132770077 1570 0
H3K4me3 colorectalcancer 132588734 132589482 748 0
H3ac HepG2E 132588553 132589797 1244 0
Nanog hESGSE18292 132680961 132681651 690 0
Nanog hESGSE18292 132755729 132756318 589 0
Oct1 H2O2-HelaGSE14283 132634946 132634974 28 0
Oct1 H2O2-HelaGSE14283 132716558 132716585 27 0
Oct1 H2O2-HelaGSE14283 132736119 132736148 29 0
Oct1 H2O2-HelaGSE14283 132783920 132783953 33 0
Oct1 H2O2-HelaGSE14283 132815348 132815376 28 0
Oct1 HelaGSE14283 132628598 132628664 66 0
Oct1 HelaGSE14283 132634948 132634987 39 0
Oct1 HelaGSE14283 132697598 132697695 97 0
Oct1 HelaGSE14283 132714131 132714165 34 0
Oct1 HelaGSE14283 132715251 132715292 41 0
Oct1 HelaGSE14283 132720154 132720186 32 0
Oct1 HelaGSE14283 132769072 132769115 43 0
Oct1 HelaGSE14283 132777863 132777894 31 0
Oct1 HelaGSE14283 132802237 132802268 31 0
Oct1 HelaGSE14283 132805784 132805818 34 0
Oct1 HelaGSE14283 132815340 132815378 38 0
P300 T0-glioblastomaGSE21026 132588078 132588935 857 0
P300 T30-glioblastomaGSE21026 132587924 132588819 895 0
PHF8 293TGSE20725 132588091 132588932 841 0
PHF8 HeLaGSE20725 132588297 132588891 594 0
RNAII Tamoxifen-MCF7GSE14664 132605743 132605803 60 0
RNAII Tamoxifen-MCF7GSE14664 132724832 132724869 37 0
TFAP2C MCF7GSE21234 132636350 132636796 446 0
hScc1 BcellGSE12603 132769616 132770118 502 0
hScc1 CdLSGSE12603 132769572 132770154 582 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
24668 mRNA SEC8L1 chr7 132395083 133207766 24396 mRNA chr7 132942500 132966896 Non-exonic Bidirectional (NOB) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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