Annotation Detail for RPLP1

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Basic Information Top

Gene Symbol:	RPLP1 ( FLJ27448,MGC5215,P1,RPP1 )
Gene Full Name:	ribosomal protein, large, P1
Band:	15q23
Quick Links	Entrez ID:6176; OMIM: 180520; Uniprot ID:RLA1_HUMAN; ENSEMBL ID: ENSG00000137818; HGNC ID: 10372
Relate to Another Database:	SFARIGene; denovo-db

Pathways, Diseases and Drugs

TF binding site

Post Translation Modification

PTM Sites from Uniprot:6 results
Experimental PTM Sites from dbPTM:4 results
Predicted PTM Sites by profile HMM from dbPTM:6 results

Location(AA)	Modification
2	N-acetylalanine.
5	Phosphoserine.
11	Phosphotyrosine.
12	Phosphoserine.
101	Phosphoserine.
104	Phosphoserine.

Location(AA)	Modification	Resource
83	O-linked	HMM predict
96	Alanine	HMM predict
101	Phosphoserine(CK1)	HMM predict
101	Phosphoserine(CK2)	HMM predict
104	Phosphoserine(ATM)	HMM predict
104	Phosphoserine	HMM predict

Validated transcription factor binding site by ChIP-Chip and ChIP-Seq

RefSeq ID: NM_001003
Location:chr15 67532212-67534937
strand:+

Upstream the gene:6 results
Downstream the gene:18 results
Inside the gene:12 results

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
Fos	K562	GSE19551	67531252	67532415	1163	379
H3ac	HepG2	E	67531161	67532087	926	589
NFkBII	GM15510	GSE19485	67531235	67533113	1878	39
PHF8	293T	GSE20725	67531252	67532983	1731	95
TAFII	hES	GSE17917	67531896	67532522	626	4
hScc1	Bcell	GSE12603	67531785	67532521	736	60

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
AR	prostate-cancer	GSE14092	67554415	67554995	580	19768
CTCF	CD4	GSE12889	67542082	67542402	320	7305
CTCF	CD4	SISSRdata	67542082	67542402	320	7305
CTCF	G2	GSE9613	67542127	67542695	568	7474
CTCF	G2	GSE9613	67545340	67545656	316	10561
FOXA1	MCF7	GSE15244	67545516	67546066	550	10854
FOXA1	MCF7	GSE15244	67546700	67549170	2470	12998
FOXA1	eGFP	GSE10845	67545516	67546066	550	10854
FOXA1	eGFP	GSE10845	67546700	67549170	2470	12998
FoxA1	MCF7	MACSdata	67545454	67545682	228	10631
FoxA1	MCF7	MACSdata	67546899	67547542	643	12283
Pol2	GM12878	GSE19551	67535512	67537542	2030	1590
RARA	MCF7	GSE15244	67542127	67542998	871	7625
RARA	MCF7	GSE15244	67546700	67548367	1667	12596
TFAP2C	MCF7	GSE21234	67541251	67541791	540	6584
TFAP2C	MCF7	GSE21234	67541895	67542590	695	7305
TFAP2C	MCF7	GSE21234	67546821	67547562	741	12254
hScc1	Bcell	GSE12603	67545340	67545656	316	10561

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
FOXA1	MCF7	GSE15244	67532784	67533383	599	0
FOXA1	eGFP	GSE10845	67532784	67533383	599	0
H3K4me3	colorectal	cancer	67532674	67533383	709	0
H3K4me3	colorectal	cancer	67533758	67534227	469	0
H3ac	HepG2	E	67532710	67533383	673	0
H3ac	HepG2	E	67533724	67534493	769	0
P300	T30-glioblastoma	GSE21026	67531796	67533222	1426	0
PHF8	HeLa	GSE20725	67531414	67533214	1800	0
Pol2	GM12878	GSE19551	67531252	67533179	1927	0
TAF	Hela	GSE8489	67531197	67533383	2186	0
TAF	Hela	GSE8489	67533724	67534457	733	0
TAF	k562	GSE8489	67532784	67533383	599	0

Validated miRNA targets

Cis-Nats regulation

Simple Query:

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

Studies: 1,036
Genes: 1,379
CNVs/SVs: 5,420
SNVs/Indels: 11,669
de novo Mutations: 5,669
Mosaics: 789
Linkage Regions: 172

Paper Collected: 6/30/2018

Last Update: 8/26/2018

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