AutismKB 2.0

Annotation Detail for RPS6


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Basic Information Top
Gene Symbol:RPS6 ( - )
Gene Full Name: ribosomal protein S6
Band: 9p22.1
Quick LinksEntrez ID:6194; OMIM: 180460; Uniprot ID:RS6_HUMAN; ENSEMBL ID: ENSG00000137154; HGNC ID: 10429
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
30N6-acetyllysine.
78Phosphoserine.
148Phosphoserine.
211N6-acetyllysine.
235Phosphoserine.
236Phosphoserine.
240Phosphoserine.
244Phosphoserine.
246Phosphoserine (By similarity).
247Phosphoserine.
Location(AA) Modifications Resource
235Phosphoserine.Swiss-Prot 53.0
235Phosphoserine (PKC delta;p7)Phospho.ELM 6.0
236Phosphoserine (PKC delta;p7)Phospho.ELM 6.0
236Phosphoserine.Swiss-Prot 53.0
240Phosphoserine.Swiss-Prot 53.0
240PhosphoserinePhospho.ELM 6.0
242PhosphoserinePhospho.ELM 6.0
244Phosphoserine (By similarity).Swiss-Prot 53.0
244PhosphoserinePhospho.ELM 6.0
246Phosphoserine (By similarity).Swiss-Prot 53.0
247Phosphoserine (By similarity).Swiss-Prot 53.0
247PhosphoserinePhospho.ELM 6.0
Location(AA) Modification Resource
28Phosphotyrosine(Syk)HMM predict
84Phosphotyrosine(Jak)HMM predict
89Phosphothreonine(PKC)HMM predict
96PhosphoserineHMM predict
146N-linkedHMM predict
199Phosphothreonine(PKC)HMM predict
235PhosphoserineHMM predict
235Phosphoserine(PKG)HMM predict
235Phosphoserine(PKA)HMM predict
236Phosphoserine(PKB)HMM predict
236Phosphoserine(PKC)HMM predict
240PhosphoserineHMM predict
240O-linkedHMM predict
242Phosphoserine(IKK)HMM predict
244Phosphoserine(IKK)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001010
  • Location:chr9 19366253-19370234
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3K4me3 colorectalcancer 19370867 19371050 183 724
H3ac HepG2E 19370867 19371050 183 724
KLF4 hESGSE17917 19370175 19370401 226 54
PHF8 293TGSE20725 19369590 19371017 1427 69
p130 QuiescentGSE19898 19370048 19370685 637 132
p130 shRbQuiescentGSE19898 19369977 19370865 888 187
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ER E2-MCF7GSE14664 19368448 19368480 32 0
ETS1 JurkatGSE17954 19369477 19370907 1430 0
FOXA1 MCF7GSE15244 19369709 19370535 826 0
GABP k562GSE8489 19368441 19370535 2094 0
H3K4me3 colorectalcancer 19368158 19369958 1800 0
H3ac HepG2E 19367087 19370535 3448 0
NFkBII GM12878GSE19485 19368607 19371407 2800 0
NFkBII GM12892GSE19485 19368950 19371061 2111 0
NFkBII GM15510GSE19485 19369432 19370998 1566 0
PHF8 Hs68minusFBSGSE20725 19369466 19370844 1378 0
PHF8 Hs68plusFBSGSE20725 19369362 19370800 1438 0
Pol2 GM12878GSE19551 19369655 19370615 960 0
PolII HeLaGSE12783 19367723 19370965 3242 0
TAF HelaGSE8489 19368477 19370451 1974 0
TAF k562GSE8489 19366366 19367475 1109 0
TAF k562GSE8489 19367835 19370535 2700 0
TAFII hESGSE17917 19369759 19370663 904 0
hScc1 BcellGSE12603 19369673 19370535 862 0
hScc1 CdLSGSE12603 19369600 19370535 935 0
p130 QuiescentGSE19898 19369674 19370044 370 0
p130 SenescentGSE19898 19369808 19370555 747 0
p130 shRbSenescentGSE19898 19369631 19370622 991 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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