AutismKB 2.0

Annotation Detail for RREB1


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Basic Information Top
Gene Symbol:RREB1 ( FINB,HNT,LZ321,RREB-1,Zep-1 )
Gene Full Name: ras responsive element binding protein 1
Band: 6p24.3
Quick LinksEntrez ID:6239; OMIM: 602209; Uniprot ID:RREB1_HUMAN; ENSEMBL ID: ENSG00000124782; HGNC ID: 10449
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
36Phosphoserine.
42Phosphoserine.
231Phosphoserine.
1122Phosphoserine.
1134Phosphoserine (By similarity).
1135Phosphoserine (By similarity).
1167Phosphoserine.
1174Phosphoserine.
1175Phosphoserine.
1219Phosphoserine.
1225Phosphoserine.
1315Phosphothreonine.
1388Phosphoserine.
1653Phosphoserine.
Location(AA) Modifications Resource
236Phosphoserine.Swiss-Prot 53.0
Location(AA) Modification Resource
21Phosphothreonine(MAPK)HMM predict
34Phosphoserine(CK1)HMM predict
34O-linkedHMM predict
35O-linkedHMM predict
39O-linkedHMM predict
47O-linkedHMM predict
69O-linkedHMM predict
69O-linkedHMM predict
69O-linkedHMM predict
69Phosphothreonine(MAPK)HMM predict
102O-linkedHMM predict
162O-linkedHMM predict
165O-linkedHMM predict
166N-linkedHMM predict
167O-linkedHMM predict
168O-linkedHMM predict
172Phosphoserine(IKK)HMM predict
172O-linkedHMM predict
185O-linkedHMM predict
185Phosphothreonine(MAPK)HMM predict
189O-linkedHMM predict
189O-linkedHMM predict
189O-linkedHMM predict
191Phosphoserine(MAPK)HMM predict
191Phosphoserine(IKK)HMM predict
204O-linkedHMM predict
204Phosphoserine(CDK)HMM predict
204Phosphoserine(CDC2)HMM predict
209Phosphoserine(MAPK)HMM predict
209Phosphoserine(CDC2)HMM predict
209Phosphoserine(IKK)HMM predict
218Phosphothreonine(PKC)HMM predict
233MethylarginineHMM predict
236Phosphoserine(PKG)HMM predict
273Phosphothreonine(CK2)HMM predict
294Phosphoserine(ATM)HMM predict
294Phosphoserine(IKK)HMM predict
340Phosphoserine(CAMK2)HMM predict
342Phosphoserine(CK2)HMM predict
401PhosphoserineHMM predict
456Phosphoserine(ATM)HMM predict
466S-palmitoylHMM predict
497Phosphothreonine(CK2)HMM predict
504Phosphoserine(ATM)HMM predict
504O-linkedHMM predict
504Phosphoserine(CDC2)HMM predict
516Phosphothreonine(MAPK)HMM predict
543Phosphoserine(ATM)HMM predict
554Phosphoserine(CK1)HMM predict
554Phosphoserine(CK2)HMM predict
557Phosphoserine(CK2)HMM predict
567Phosphoserine(IKK)HMM predict
567Phosphoserine(CDC2)HMM predict
585S-palmitoylHMM predict
618Phosphothreonine(PKC)HMM predict
643Phosphoserine(CK2)HMM predict
655N-linkedHMM predict
657Phosphoserine(CK1)HMM predict
666Phosphoserine(CK2)HMM predict
683Phosphothreonine(PKC)HMM predict
749Phosphoserine(ATM)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001003698
  • Location:chr6 7053262-7196193
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 7051972 7052160 188 1197
H3ac HepG2E 7051393 7051833 440 1650
TAF HelaGSE8489 7034042 7034490 448 18997
hScc1 BcellGSE12603 7046528 7046827 299 6585
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 7053394 7054149 755 0
ER MCF7GSE19013 7066691 7067353 662 0
FoxA1 MCF7MACSdata 7084224 7084580 356 0
H3ac HepG2E 7053104 7053460 356 0
H3ac HepG2E 7054977 7055740 763 0
KLF4 hESGSE17917 7054161 7054379 218 0
KLF4 hESGSE17917 7059606 7059761 155 0
Myc K562GSE19551 7064461 7065235 774 0
Nanog hESGSE18292 7069625 7070232 607 0
Oct1 H2O2-HelaGSE14283 7064686 7064714 28 0
Oct1 HelaGSE14283 7069260 7069291 31 0
TAF k562GSE8489 7055195 7056783 1588 0
TAF k562GSE8489 7064598 7065009 411 0
TFAP2C MCF7GSE21234 7057991 7058728 737 0
TFAP2C MCF7GSE21234 7074469 7075134 665 0
hScc1 BcellGSE12603 7053142 7053804 662 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-143 hsa-mir-143 5 21159816
hsa-miR-143* hsa-mir-143 5 21159816
hsa-miR-145 hsa-mir-145 5 21159816
hsa-miR-145* hsa-mir-145 5 21159816
hsa-miR-155 hsa-mir-155 21 20680360
hsa-miR-155* hsa-mir-155 21 20680360
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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