AutismKB 2.0

Annotation Detail for RRM1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:RRM1 ( R1,RIR1,RR1 )
Gene Full Name: ribonucleotide reductase M1
Band: 11p15.4
Quick LinksEntrez ID:6240; OMIM: 180410; Uniprot ID:RIR1_HUMAN; ENSEMBL ID: ENSG00000167325; HGNC ID: 10451
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
17N6-acetyllysine.
376N6-acetyllysine.
Location(AA) Modifications Resource
Location(AA) Modification Resource
66O-linkedHMM predict
68Phosphothreonine(PKC)HMM predict
68O-linkedHMM predict
104SulfotyrosineHMM predict
104Phosphotyrosine(INSR)HMM predict
120Phosphothreonine(PKC)HMM predict
199Phosphothreonine(PKC)HMM predict
280N-linkedHMM predict
281N-linkedHMM predict
461Phosphotyrosine(SRC)HMM predict
486SulfotyrosineHMM predict
553Phosphotyrosine(Syk)HMM predict
556Phosphotyrosine(Syk)HMM predict
572N-linkedHMM predict
663N-linkedHMM predict
717Phosphotyrosine(EGFR)HMM predict
764Phosphoserine(CK2)HMM predict
764Phosphoserine(PKG)HMM predict
774Phosphothreonine(PKA)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001033
  • Location:chr11 4072586-4116680
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
P300 T0-glioblastomaGSE21026 4071965 4072781 816 214
PHF8 293TGSE20725 4071884 4073170 1286 60
VDR GM10855-UnstimGSE22484 4071664 4073208 1544 151
VDR GM10855-stimGSE22484 4071717 4073230 1513 113
p130 shRbQuiescentGSE19898 4071670 4072968 1298 268
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
E2F4 G0GSE7516 4072193 4073464 1271 0
ER E2-MCF7GSE14664 4116327 4116398 71 0
ETS1 JurkatGSE17954 4072111 4073234 1123 0
FOXA1 DLD1GSE12801 4112573 4113243 670 0
H3K4me3 colorectalcancer 4073540 4074331 791 0
H3ac HepG2E 4073274 4074407 1133 0
LIN9 G0GSE7516 4071919 4073464 1545 0
LIN9 SGSE7516 4071752 4073652 1900 0
Oct1 HelaGSE14283 4094413 4094460 47 0
P300 T30-glioblastomaGSE21026 4071933 4074145 2212 0
P300 T30-glioblastomaGSE21026 4112404 4113317 913 0
hScc1 CdLSGSE12603 4072742 4073055 313 0
p130 QuiescentGSE19898 4072238 4073176 938 0
p130 SenescentGSE19898 4072106 4073070 964 0
p130 shRbSenescentGSE19898 4072096 4073211 1115 0
p130 G0GSE7516 4072083 4073274 1191 0
p130 SGSE7516 4072308 4073359 1051 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
4002 mRNA RRM1 chr11 4072586 4116681 99 HTC chr11 4111810 4112986Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018