AutismKB 2.0

Annotation Detail for RTN2


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Basic Information Top
Gene Symbol:RTN2 ( NSP2,NSPL1 )
Gene Full Name: reticulon 2
Band: 19q13.32
Quick LinksEntrez ID:6253; OMIM: 603183; Uniprot ID:RTN2_HUMAN; ENSEMBL ID: ENSG00000125744; HGNC ID: 10468
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
44Phosphoserine (By similarity).
Location(AA) Modifications Resource
44Phosphoserine (By similarity).Swiss-Prot 53.0
Location(AA) Modification Resource
16O-linkedHMM predict
19O-linkedHMM predict
20O-linkedHMM predict
21O-linkedHMM predict
21Phosphothreonine(CDK)HMM predict
21Phosphothreonine(MAPK)HMM predict
44Phosphoserine(CK1)HMM predict
53Phosphoserine(ATM)HMM predict
53Phosphoserine(CK1)HMM predict
92Phosphoserine(IKK)HMM predict
114Phosphoserine(CK1)HMM predict
116Phosphoserine(ATM)HMM predict
118Phosphoserine(CDC2)HMM predict
118Phosphoserine(ATM)HMM predict
160Phosphoserine(IKK)HMM predict
160O-linkedHMM predict
161O-linkedHMM predict
163Phosphoserine(CK1)HMM predict
163O-linkedHMM predict
166Phosphothreonine(CDK)HMM predict
199Phosphoserine(CDK)HMM predict
199Phosphoserine(MAPK)HMM predict
199Phosphoserine(CDC2)HMM predict
204Phosphothreonine(CDK)HMM predict
208O-linkedHMM predict
211O-linkedHMM predict
218O-linkedHMM predict
218O-linkedHMM predict
218Phosphothreonine(MAPK)HMM predict
220Phosphoserine(CDK)HMM predict
220Phosphoserine(CDC2)HMM predict
227Phosphoserine(IKK)HMM predict
229Phosphoserine(CK2)HMM predict
314Phosphothreonine(CDK)HMM predict
326Phosphoserine(CDC2)HMM predict
330O-linkedHMM predict
416Phosphotyrosine(Syk)HMM predict
441Phosphoserine(PKG)HMM predict
441Phosphoserine(CAMK2)HMM predict
532O-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_005619
  • Location:chr19 50680390-50692150
  • strand:-
No data
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 50688596 50688873 277 0
CTCF CD4SISSRdata 50688596 50688873 277 0
NRSF JurkatGSE13047 50690712 50692128 1416 0
NRSF mAbJurkat 50688804 50691599 2795 0
NRSF-mono JurkatQuESTdata 50690999 50692050 1051 0
NRSF-poly JurkatQuESTdata 50690832 50692311 1479 0
Oct1 H2O2-HelaGSE14283 50691071 50691098 27 0
PolII HeLaGSE12783 50691155 50692908 1753 0
hScc1 BcellGSE12603 50691461 50691975 514 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
13351 EST chr19 50683874 50697388 132 mRNA RTN2 chr19 50680389 50692151Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018