AutismKB 2.0

Annotation Detail for RXRA


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Basic Information Top
Gene Symbol:RXRA ( FLJ00280,FLJ00318,FLJ16020,FLJ16733,MGC102720,NR2B1 )
Gene Full Name: retinoid X receptor, alpha
Band: 9q34.2
Quick LinksEntrez ID:6256; OMIM: 180245; Uniprot ID:RXRA_HUMAN; ENSEMBL ID: ENSG00000186350; HGNC ID: 10477
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
21Phosphoserine (By similarity).
27Phosphoserine.
56Phosphoserine; by MAPK8 and MAPK9 (By
70Phosphoserine; by MAPK8 and MAPK9 (By
82Phosphothreonine; by MAPK8 and MAPK9 (By
260Phosphoserine; by MAPK8 and MAPK9 (By
Location(AA) Modifications Resource
32PhosphoserinePhospho.ELM 6.0
82Phosphothreonine (MAPK
108Glycyl lysine isopeptide (Lys-Gly)(interchain with G-Cter in SUMO).Swiss-Prot 53.0
249Phosphotyrosine (MAP2K4)Phospho.ELM 6.0
260Phosphoserine (MAPK1;MAPK3;)Phospho.ELM 6.0
Location(AA) Modification Resource
16N-linkedHMM predict
18O-linkedHMM predict
21Phosphoserine(MAPK)HMM predict
21Phosphoserine(CDC2)HMM predict
53O-linkedHMM predict
53Phosphothreonine(PKC)HMM predict
56Phosphoserine(CDC2)HMM predict
66O-linkedHMM predict
69O-linkedHMM predict
70Phosphoserine(CDC2)HMM predict
78O-linkedHMM predict
78Phosphoserine(IKK)HMM predict
95O-linkedHMM predict
96Phosphoserine(CDC2)HMM predict
103Phosphoserine(CK1)HMM predict
169Phosphotyrosine(INSR)HMM predict
249Phosphotyrosine(INSR)HMM predict
249Phosphotyrosine(SRC)HMM predict
257N-linkedHMM predict
260Phosphoserine(ATM)HMM predict
262N-linkedHMM predict
397Phosphotyrosine(EGFR)HMM predict
397Phosphotyrosine(SRC)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_002957
  • Location:chr9 136358230-136472252
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
TFAP2C MCF7GSE21234 136347259 136348026 767 10588
TFAP2C MCF7GSE21234 136352007 136352610 603 5922
hScc1 BcellGSE12603 136338742 136339039 297 19340
hScc1 BcellGSE12603 136346574 136347034 460 11427
hScc1 BcellGSE12603 136349588 136350609 1021 8132
hScc1 BcellGSE12603 136356777 136357722 945 981
p63 keratinocytesGSE17611 136355379 136356405 1026 2339
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 136474993 136475306 313 2897
CTCF CD4GSE12889 136481164 136481543 379 9101
CTCF CD4SISSRdata 136474993 136475306 313 2897
CTCF CD4SISSRdata 136481164 136481543 379 9101
CTCF HelaGSE12889 136481151 136481503 352 9075
CTCF JurkatGSE12889 136475019 136475356 337 2935
GABP GMOGSE8489 136488668 136489541 873 16852
GABP HepG2GSE8489 136488668 136489541 873 16852
P300 T30-glioblastomaGSE21026 136474955 136475584 629 3017
P300 T30-glioblastomaGSE21026 136480930 136481778 848 9102
P300 T30-glioblastomaGSE21026 136487582 136488838 1256 15958
SRF GMOGSE8489 136488668 136489541 873 16852
SRF HepG2GSE8489 136488668 136489507 839 16835
TFAP2C MCF7GSE21234 136473896 136475586 1690 2489
TFAP2C MCF7GSE21234 136487890 136488529 639 15957
hScc1 BcellGSE12603 136474747 136475450 703 2846
hScc1 BcellGSE12603 136481153 136481703 550 9176
hScc1 CdLSGSE12603 136474814 136475576 762 2943
hScc1 CdLSGSE12603 136480958 136481703 745 9078
hScc1 G2GSE9613 136474229 136475944 1715 2834
hScc1 G2GSE9613 136480486 136481703 1217 8842
p130 QuiescentGSE19898 136488330 136488519 189 16172
p130 SenescentGSE19898 136487091 136488823 1732 15705
p130 shRbQuiescentGSE19898 136487398 136488865 1467 15879
p130 shRbSenescentGSE19898 136487116 136488798 1682 15705
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP JurkatGSE17954 136436781 136440127 3346 0
CBP T0-glioblastomaGSE21026 136466274 136466985 711 0
CBP T30-glioblastomaGSE21026 136392563 136393245 682 0
CBP T30-glioblastomaGSE21026 136411677 136412071 394 0
CBP T30-glioblastomaGSE21026 136445275 136446172 897 0
CBP T30-glioblastomaGSE21026 136466286 136466994 708 0
CTCF CD4GSE12889 136396080 136396253 173 0
CTCF CD4GSE12889 136413412 136413572 160 0
CTCF CD4GSE12889 136431241 136431407 166 0
CTCF CD4GSE12889 136439029 136439179 150 0
CTCF CD4SISSRdata 136396080 136396253 173 0
CTCF CD4SISSRdata 136413412 136413572 160 0
CTCF CD4SISSRdata 136431241 136431407 166 0
CTCF CD4SISSRdata 136439029 136439179 150 0
CTCF HelaGSE12889 136431193 136431394 201 0
ER Breast-CancerGSE22609 136390955 136391445 490 0
ER MCF7GSE19013 136369744 136370377 633 0
ER MCF7GSE19013 136388381 136389076 695 0
ER MCF7GSE19013 136390901 136391599 698 0
ER MCF7GSE19013 136399505 136399870 365 0
ER MCF7GSE19013 136411436 136412283 847 0
ER MCF7GSE19013 136427258 136427672 414 0
ER MCF7GSE19013 136443872 136444493 621 0
Gata1 K562GSE18868 136369883 136370653 770 0
Gata2 K562GSE18868 136369838 136371412 1574 0
Gata2 K562GSE18868 136388518 136389236 718 0
KLF4 hESGSE17917 136464354 136464730 376 0
NFkBII GM10847GSE19485 136421752 136424419 2667 0
NFkBII GM12878GSE19485 136421940 136424116 2176 0
NFkBII GM12878GSE19485 136459401 136460827 1426 0
NFkBII GM12892GSE19485 136421698 136424467 2769 0
NFkBII GM15510GSE19485 136421963 136424403 2440 0
NFkBII GM18526GSE19485 136421866 136424383 2517 0
NRSF JurkatGSE13047 136365790 136366278 488 0
NRSF JurkatGSE13047 136457326 136457929 603 0
NRSF-mono JurkatQuESTdata 136365817 136366277 460 0
NRSF-mono JurkatQuESTdata 136457295 136457900 605 0
NRSF-poly JurkatQuESTdata 136365625 136366334 709 0
NRSF-poly JurkatQuESTdata 136457289 136457860 571 0
P300 T0-glioblastomaGSE21026 136445398 136445951 553 0
P300 T0-glioblastomaGSE21026 136466472 136466908 436 0
P300 T30-glioblastomaGSE21026 136392313 136393143 830 0
P300 T30-glioblastomaGSE21026 136418790 136419460 670 0
P300 T30-glioblastomaGSE21026 136438533 136439624 1091 0
P300 T30-glioblastomaGSE21026 136445048 136446345 1297 0
P300 T30-glioblastomaGSE21026 136466073 136466961 888 0
RARA MCF7GSE15244 136388057 136389620 1563 0
Rb QuiescentGSE19898 136439027 136439291 264 0
Rb QuiescentGSE19898 136466534 136466754 220 0
Rb SenescentGSE19898 136438903 136439281 378 0
Rb SenescentGSE19898 136466413 136466780 367 0
Rb shRbQuiescentGSE19898 136457498 136457680 182 0
Rb shRbQuiescentGSE19898 136466363 136466777 414 0
Rb shRbSenescenceGSE19898 136466529 136466805 276 0
TFAP2C MCF7GSE21234 136359265 136360600 1335 0
TFAP2C MCF7GSE21234 136382139 136382655 516 0
TFAP2C MCF7GSE21234 136387037 136391668 4631 0
TFAP2C MCF7GSE21234 136395015 136395458 443 0
TFAP2C MCF7GSE21234 136399279 136400736 1457 0
TFAP2C MCF7GSE21234 136405782 136407684 1902 0
TFAP2C MCF7GSE21234 136410367 136412370 2003 0
TFAP2C MCF7GSE21234 136420311 136421206 895 0
TFAP2C MCF7GSE21234 136428971 136429516 545 0
TFAP2C MCF7GSE21234 136441734 136442913 1179 0
TFAP2C MCF7GSE21234 136442928 136446465 3537 0
hScc1 BcellGSE12603 136358593 136358904 311 0
hScc1 BcellGSE12603 136360549 136360856 307 0
hScc1 BcellGSE12603 136370788 136371039 251 0
hScc1 BcellGSE12603 136373341 136374298 957 0
hScc1 BcellGSE12603 136388487 136388917 430 0
hScc1 BcellGSE12603 136395164 136395519 355 0
hScc1 BcellGSE12603 136431299 136432464 1165 0
hScc1 BcellGSE12603 136435666 136436307 641 0
hScc1 BcellGSE12603 136437480 136437679 199 0
hScc1 BcellGSE12603 136438776 136439104 328 0
hScc1 BcellGSE12603 136443279 136443707 428 0
hScc1 BcellGSE12603 136451480 136452027 547 0
hScc1 BcellGSE12603 136454019 136454247 228 0
hScc1 BcellGSE12603 136466882 136467512 630 0
hScc1 BcellGSE12603 136470184 136471116 932 0
p130 QuiescentGSE19898 136466534 136466778 244 0
p130 SenescentGSE19898 136438803 136439217 414 0
p130 SenescentGSE19898 136439779 136440033 254 0
p130 SenescentGSE19898 136466393 136466859 466 0
p130 shRbQuiescentGSE19898 136371144 136371995 851 0
p130 shRbQuiescentGSE19898 136466535 136467068 533 0
p130 shRbSenescentGSE19898 136438768 136439307 539 0
p130 shRbSenescentGSE19898 136466388 136466740 352 0
p63 keratinocytesGSE17611 136403019 136404010 991 0
p63 keratinocytesGSE17611 136411447 136412450 1003 0
p63 keratinocytesGSE17611 136443505 136445349 1844 0
p63 keratinocytesGSE17611 136463840 136464724 884 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-107 hsa-mir-107 10 20348243
hsa-miR-125b hsa-mir-125b-1 11 20306291
hsa-miR-125b-1* hsa-mir-125b-1 11 20306291
hsa-miR-424 hsa-mir-424 X 20348243
hsa-miR-424* hsa-mir-424 X 20348243
hsa-miR-570 hsa-mir-570 3 20348243
hsa-miR-618 hsa-mir-618 12 20348243
hsa-miR-646 hsa-mir-646 20 20306291
hsa-miR-760 hsa-mir-760 1 20348243
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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