Annotation Detail for RYK
Basic Information Top
| Gene Symbol: | RYK ( D3S3195,JTK5,JTK5A,RYK1 ) |
|---|---|
| Gene Full Name: | RYK receptor-like tyrosine kinase |
| Band: | 3q22.2 |
| Quick Links | Entrez ID:6259; OMIM: 600524; Uniprot ID:RYK_HUMAN; ENSEMBL ID: ENSG00000163785; HGNC ID: 10481 |
| Relate to Another Database: | SFARIGene; denovo-db |
| Location(AA) | Modification | |
|---|---|---|
| 136 | N-linked (GlcNAc...) (Potential). | |
| 171 | N-linked (GlcNAc...) (Potential). | |
| 175 | N-linked (GlcNAc...) (Potential). | |
| 179 | N-linked (GlcNAc...) (Potential). | |
| 206 | N-linked (GlcNAc...) (Potential). | |
| 492 | Phosphotyrosine; by autocatalysis (By | |
| Location(AA) | Modifications | Resource |
|---|---|---|
| 136 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 |
| 171 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 |
| 175 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 |
| 179 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 |
| 206 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 |
| 492 | Phosphotyrosine (by autocatalysis) (Bysimilarity). | Swiss-Prot 53.0 |
| Location(AA) | Modification | Resource |
|---|---|---|
| 56 | O-linked | HMM predict |
| 171 | N-linked | HMM predict |
| 175 | N-linked | HMM predict |
| 179 | N-linked | HMM predict |
| 184 | N-linked | HMM predict |
| 206 | N-linked | HMM predict |
| 212 | Phosphotyrosine(Syk) | HMM predict |
| 223 | O-linked | HMM predict |
| 260 | Phosphoserine(IKK) | HMM predict |
| 267 | Phosphoserine(ATM) | HMM predict |
| 271 | Phosphoserine(IKK) | HMM predict |
| 271 | Phosphoserine(ATM) | HMM predict |
| 274 | O-linked | HMM predict |
| 288 | N-linked | HMM predict |
| 297 | Phosphothreonine(PKC) | HMM predict |
| 540 | Phosphotyrosine(Syk) | HMM predict |
| 590 | Valine | HMM predict |
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq| Micro RNA Name | Stem Loop Name | The chromosome that miRNA located | Publication |
|---|---|---|---|
| hsa-miR-1 | hsa-mir-1-2 | 18 | 15685193 |
| hsa-miR-1 | hsa-mir-1-1 | 20 | 15685193 |
| hsa-miR-124 | hsa-mir-124-1 | 8 | 15685193 |
| hsa-miR-124 | hsa-mir-124-2 | 8 | 15685193 |
| hsa-miR-124 | hsa-mir-124-3 | 20 | 15685193 |
| hsa-miR-373 | hsa-mir-373 | 19 | 15685193 |
| hsa-miR-373* | hsa-mir-373 | 19 | 15685193 |
| ID in Tarbase | Data Type | Support Type | miRNA | Gene | Direct Support | Publication |
|---|---|---|---|---|---|---|
| 251 | Unknown | MicroArray | miR-124 | RYK | n_a | 15685193 |
| Ensembl | Protein Type | Differentially expressed in | Pathology or Event | Mis Regulation | Gene Expression | Tumour Involvement |
| ENSG00000163785 | G1-to-S transition | n_a | n_a | "epithelium, lymphocyte, muscle cell" | "benign tumour, malignant tumour, carcinoma, leukaemia, sarcoma" |