AutismKB 2.0

Annotation Detail for BDNF


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Basic Information Top
Gene Symbol:BDNF ( MGC34632 )
Gene Full Name: brain-derived neurotrophic factor
Band: 11p14.1
Quick LinksEntrez ID:627; OMIM: 113505; Uniprot ID:BDNF_HUMAN; ENSEMBL ID: ENSG00000176697; HGNC ID: 1033
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
121N-linked (GlcNAc...).
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_170731
  • Location:chr11 27633017-27699871
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3K27me3 colorectalcancer 27697936 27702089 4153 141
Nanog ESGSE20650 27718488 27719261 773 19003
Nanog hESGSE18292 27718800 27719400 600 19229
Sox2 hESGSE18292 27718891 27719270 379 19209
hScc1 CdLSGSE12603 27701810 27702159 349 2113
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-let-7d hsa-let-7d 9 19703567
hsa-let-7d* hsa-let-7d 9 19703567
hsa-miR-1 hsa-mir-1-2 18 14697198
hsa-miR-1 hsa-mir-1-1 20 14697198
hsa-miR-101 hsa-mir-101-1 1 14697198
hsa-miR-101 hsa-mir-101-2 9 14697198
hsa-miR-107 hsa-mir-107 10 18632683
hsa-miR-10a hsa-mir-10a 17 20309390
hsa-miR-10a* hsa-mir-10a 17 20309390
hsa-miR-124 hsa-mir-124-1 8 19703567
hsa-miR-124 hsa-mir-124-2 8 19703567
hsa-miR-124 hsa-mir-124-3 20 19703567
hsa-miR-130a hsa-mir-130a 11 14697198
hsa-miR-130a* hsa-mir-130a 11 14697198
hsa-miR-132 hsa-mir-132 17 20307261
hsa-miR-132 hsa-mir-132 17 19958814
hsa-miR-132 hsa-mir-132 17 17994015
hsa-miR-132* hsa-mir-132 17 20307261
hsa-miR-132* hsa-mir-132 17 19958814
hsa-miR-132* hsa-mir-132 17 17994015
hsa-miR-134 hsa-mir-134 14 20622856
hsa-miR-138 hsa-mir-138-2 16 21168126
hsa-miR-138 hsa-mir-138-1 3 21168126
hsa-miR-138-2* hsa-mir-138-2 16 21168126
hsa-miR-148a hsa-mir-148a 7 21168126
hsa-miR-148a* hsa-mir-148a 7 21168126
hsa-miR-15a hsa-mir-15a 13 19416898
hsa-miR-15a* hsa-mir-15a 13 19416898
hsa-miR-181a hsa-mir-181a-2 9 19703567
hsa-miR-181a hsa-mir-181a-1 1 19703567
hsa-miR-182 hsa-mir-182 7 19416898
hsa-miR-182* hsa-mir-182 7 19416898
hsa-miR-18a hsa-mir-18a 13 19416898
hsa-miR-18a* hsa-mir-18a 13 19416898
hsa-miR-191 hsa-mir-191 3 18632683
hsa-miR-191* hsa-mir-191 3 18632683
hsa-miR-195 hsa-mir-195 17 19121517
hsa-miR-195 hsa-mir-195 17 18632683
hsa-miR-195* hsa-mir-195 17 19121517
hsa-miR-195* hsa-mir-195 17 18632683
hsa-miR-19a hsa-mir-19a 13 14697198
hsa-miR-19a* hsa-mir-19a 13 14697198
hsa-miR-210 hsa-mir-210 11 19826008
hsa-miR-212 hsa-mir-212 17 20711185
hsa-miR-212 hsa-mir-212 17 20307261
hsa-miR-22 hsa-mir-22 17 21168126
hsa-miR-22* hsa-mir-22 17 21168126
hsa-miR-23a hsa-mir-23a 19 14697198
hsa-miR-23a* hsa-mir-23a 19 14697198
hsa-miR-23b hsa-mir-23b 9 14697198
hsa-miR-23b* hsa-mir-23b 9 14697198
hsa-miR-26a hsa-mir-26a-1 3 14697198
hsa-miR-26a hsa-mir-26a-2 12 14697198
hsa-miR-30a hsa-mir-30a 6 18632683
hsa-miR-30a* hsa-mir-30a 6 18632683
hsa-miR-30b hsa-mir-30b 8 19416898
hsa-miR-30b* hsa-mir-30b 8 19416898
hsa-miR-339-3p hsa-mir-339 7 21168126
hsa-miR-339-5p hsa-mir-339 7 21168126
hsa-miR-34a hsa-mir-34a 1 14697198
hsa-miR-34a* hsa-mir-34a 1 14697198
hsa-miR-375 hsa-mir-375 2 20584986
hsa-miR-488 hsa-mir-488 1 21168126
hsa-miR-488* hsa-mir-488 1 21168126
hsa-miR-491-3p hsa-mir-491 9 21168126
hsa-miR-491-5p hsa-mir-491 9 21168126
hsa-miR-495 hsa-mir-495 14 18632683
hsa-miR-9 hsa-mir-9-1 1 19958814
hsa-miR-9 hsa-mir-9-2 5 19958814
hsa-miR-9 hsa-mir-9-3 15 19958814
hsa-miR-99a hsa-mir-99a 21 19416898
hsa-miR-99a* hsa-mir-99a 21 19416898
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
4251 mRNA BDNFOS chr11 27484974 27655924 222 mRNA BDNF chr11 27633019 27678552Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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