Annotation Detail for SERPINB4

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Basic Information Top

Gene Symbol:	SERPINB4 ( LEUPIN,PI11,SCCA-2,SCCA1,SCCA2 )
Gene Full Name:	serpin peptidase inhibitor, clade B (ovalbumin), member 4
Band:	18q21.33
Quick Links	Entrez ID:6318; OMIM: 600518; Uniprot ID:SPB4_HUMAN; ENSEMBL ID: ENSG00000206073; HGNC ID: 10570
Relate to Another Database:	SFARIGene; denovo-db

Pathways, Diseases and Drugs

TF binding site

Post Translation Modification

PTM Sites from Uniprot:1 results
Experimental PTM Sites from dbPTM:0 results
Predicted PTM Sites by profile HMM from dbPTM:14 results

Location(AA)	Modification
1	N-acetylmethionine.

Location(AA)	Modification	Resource
65	N-linked	HMM predict
93	N-linked	HMM predict
113	Phosphotyrosine(SRC)	HMM predict
170	N-linked	HMM predict
195	Phosphothreonine(CK2)	HMM predict
207	Phosphotyrosine(Syk)	HMM predict
356	Phosphoserine(CDC2)	HMM predict
358	Phosphoserine(CK2)	HMM predict
376	N-linked	HMM predict
379	N-linked	HMM predict
387	Phenylalanine	HMM predict
388	Phenylalanine	HMM predict
389	Phenylalanine	HMM predict
390	Phenylalanine	HMM predict

Validated transcription factor binding site by ChIP-Chip and ChIP-Seq

RefSeq ID: NM_002974
Location:chr18 59455474-59462481
strand:-

Upstream the gene:0 results
Downstream the gene:0 results
Inside the gene:3 results

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
Oct1	H2O2-Hela	GSE14283	59461164	59461196	32	0
Oct1	Hela	GSE14283	59456658	59456688	30	0
Oct1	Hela	GSE14283	59457432	59457473	41	0

Validated miRNA targets

Cis-Nats regulation

Simple Query:

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

Studies: 1,036
Genes: 1,379
CNVs/SVs: 5,420
SNVs/Indels: 11,669
de novo Mutations: 5,669
Mosaics: 789
Linkage Regions: 172

Paper Collected: 6/30/2018

Last Update: 8/26/2018

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