AutismKB 2.0

Annotation Detail for SCD


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Basic Information Top
Gene Symbol:SCD ( FADS5,MSTP008,SCD1,SCDOS )
Gene Full Name: stearoyl-CoA desaturase (delta-9-desaturase)
Band: 10q24.31
Quick LinksEntrez ID:6319; OMIM: 604031; Uniprot ID:ACOD_HUMAN; ENSEMBL ID: ENSG00000099194; HGNC ID: 10571
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
125Histidine box-1.
161Histidine box-2.
198Phosphoserine.
199Phosphothreonine.
203Phosphoserine.
302Histidine box-3.
Location(AA) Modifications Resource
Location(AA) Modification Resource
12Phosphoserine(CK1)HMM predict
15O-linkedHMM predict
18O-linkedHMM predict
19O-linkedHMM predict
21O-linkedHMM predict
55Phosphotyrosine(Syk)HMM predict
55Phosphotyrosine(INSR)HMM predict
55Phosphotyrosine(EGFR)HMM predict
55SulfotyrosineHMM predict
151Phosphotyrosine(SRC)HMM predict
218Phosphotyrosine(Jak)HMM predict
259N-linkedHMM predict
265N-linkedHMM predict
279N-linkedHMM predict
281Phosphoserine(CDC2)HMM predict
285N-linkedHMM predict
318N-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_005063
  • Location:chr10 102096761-102114576
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 102092124 102092463 339 4468
CTCF CD4SISSRdata 102092124 102092463 339 4468
Fos K562GSE19551 102096477 102096954 477 46
H3ac HepG2E 102095354 102095757 403 1206
HIF1 HypoHepG2 102096067 102096531 464 463
KLF4 hESGSE17917 102089002 102089294 292 7614
Myc hESGSE17917 102096161 102096430 269 466
hScc1 BcellGSE12603 102092061 102092569 508 4447
hScc1 BcellGSE12603 102096067 102096454 387 501
hScc1 CdLSGSE12603 102091943 102092569 626 4506
hScc1 G2GSE9613 102091907 102092569 662 4524
p130 SenescentGSE19898 102096596 102096889 293 19
p130 shRbSenescentGSE19898 102096208 102097104 896 106
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Fos K562GSE19551 102122765 102124095 1330 8854
H3K4me2 HCT116GSE10453 102120150 102120868 718 5933
H3ac HepG2E 102120219 102120974 755 6020
H3ac HepG2E 102122602 102124434 1832 8942
Oct1 H2O2-HelaGSE14283 102115390 102115419 29 828
RARA MCF7GSE15244 102114635 102114903 268 193
RARA MCF7GSE15244 102120150 102121390 1240 6194
RARA MCF7GSE15244 102122693 102124434 1741 8987
RARG MCF7GSE15244 102114670 102114903 233 210
RARG MCF7GSE15244 102120550 102121170 620 6284
RARG MCF7GSE15244 102122602 102124434 1832 8942
Rb SenescentGSE19898 102123237 102123604 367 8844
TAF HelaGSE8489 102123490 102124434 944 9386
TAF k562GSE8489 102120110 102121010 900 5984
TAF k562GSE8489 102122602 102124434 1832 8942
TFAP2C MCF7GSE21234 102122767 102124105 1338 8860
USF1 HepG2E 102122602 102124434 1832 8942
USF2 HepG2E 102122602 102124434 1832 8942
p130 QuiescentGSE19898 102123149 102123687 538 8842
p130 QuiescentGSE19898 102123692 102123901 209 9220
p130 SenescentGSE19898 102123199 102123783 584 8915
p130 shRbQuiescentGSE19898 102123281 102123956 675 9042
p130 shRbSenescentGSE19898 102123127 102124146 1019 9060
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ER Fulvestrant-MCF7GSE14664 102098327 102098373 46 0
Gata1 K562GSE18868 102108749 102109235 486 0
Gata2 K562GSE18868 102108691 102109358 667 0
H3K4me2 HCT116GSE10453 102097438 102098875 1437 0
H3ac HepG2E 102097227 102099904 2677 0
H3ac HepG2E 102100430 102101349 919 0
H3ac HepG2E 102101681 102102380 699 0
Myc K562GSE19551 102108808 102109219 411 0
Oct1 HelaGSE14283 102098320 102098395 75 0
RNAII Tamoxifen-MCF7GSE14664 102098321 102098402 81 0
TFAP2C MCF7GSE21234 102096604 102097126 522 0
USF1 HepG2E 102113589 102114903 1314 0
USF2 HepG2E 102108994 102109810 816 0
USF2 HepG2E 102113841 102114903 1062 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-195 hsa-mir-195 17 20952681
hsa-miR-195* hsa-mir-195 17 20952681
No data
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
3566 mRNA SCD chr10 102096761 102114577 691 HTC chr10 102113876 102114567Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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