Annotation Detail for BIK

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Basic Information Top

Gene Symbol:	BIK ( BIP1,BP4,NBK )
Gene Full Name:	BCL2-interacting killer (apoptosis-inducing)
Band:	22q13.2
Quick Links	Entrez ID:638; OMIM: 603392; Uniprot ID:BIK_HUMAN; ENSEMBL ID: ENSG00000100290; HGNC ID: 1051
Relate to Another Database:	SFARIGene; denovo-db

Pathways, Diseases and Drugs

TF binding site

Post Translation Modification

PTM Sites from Uniprot:1 results
Experimental PTM Sites from dbPTM:1 results
Predicted PTM Sites by profile HMM from dbPTM:2 results

Location(AA)	Modification
71	BH3.

Validated transcription factor binding site by ChIP-Chip and ChIP-Seq

RefSeq ID: NM_001197
Location:chr22 41836700-41855660
strand:+

Upstream the gene:3 results
Downstream the gene:0 results
Inside the gene:10 results

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
CTCF	CD4	GSE12889	41836435	41836616	181	175
CTCF	CD4	SISSRdata	41836435	41836616	181	175
Fos	K562	GSE19551	41829812	41830394	582	6598

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
CTCF	G2	GSE9613	41836805	41837420	615	0
FOXA1	MCF7	GSE15244	41840567	41841377	810	0
FoxA1	MCF7	MACSdata	41840944	41841189	245	0
Rb	Growing	GSE19898	41845557	41845763	206	0
STAT1	HeLa	GSE12782	41850442	41851547	1105	0
TFAP2C	MCF7	GSE21234	41839673	41840375	702	0
TFAP2C	MCF7	GSE21234	41840458	41841527	1069	0
TFAP2C	MCF7	GSE21234	41844134	41845389	1255	0
TFAP2C	MCF7	GSE21234	41852699	41853975	1276	0
hScc1	Bcell	GSE12603	41836390	41837552	1162	0

Validated miRNA targets

Cis-Nats regulation

Simple Query:

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

Studies: 1,036
Genes: 1,379
CNVs/SVs: 5,420
SNVs/Indels: 11,669
de novo Mutations: 5,669
Mosaics: 789
Linkage Regions: 172

Paper Collected: 6/30/2018

Last Update: 8/26/2018

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