AutismKB 2.0

Annotation Detail for UBE2O


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Basic Information Top
Gene Symbol:UBE2O ( E2-230K,FLJ12878,KIAA1734 )
Gene Full Name: ubiquitin-conjugating enzyme E2O
Band: 17q25.1
Quick LinksEntrez ID:63893; OMIM: NA; Uniprot ID:UBE2O_HUMAN; ENSEMBL ID: ENSG00000175931; HGNC ID: 29554
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
87Phosphoserine.
89Phosphoserine.
399Phosphoserine.
401Phosphoserine.
435Phosphothreonine.
441Phosphoserine.
836Phosphoserine.
838Phosphothreonine.
839Phosphoserine.
841Phosphothreonine.
896Phosphoserine.
Location(AA) Modifications Resource
87Phosphoserine (By similarity).Swiss-Prot 53.0
89Phosphoserine (By similarity).Swiss-Prot 53.0
836Phosphoserine (By similarity).Swiss-Prot 53.0
839Phosphoserine (By similarity).Swiss-Prot 53.0
Location(AA) Modification Resource
40O-linkedHMM predict
40Phosphoserine(CK2)HMM predict
42Phosphoserine(IKK)HMM predict
44Phosphoserine(ATM)HMM predict
44Phosphoserine(IKK)HMM predict
89Phosphoserine(CK1)HMM predict
99Phosphoserine(PKB)HMM predict
115Phosphoserine(CDC2)HMM predict
161Phosphoserine(IKK)HMM predict
320Phosphoserine(IKK)HMM predict
322Phosphoserine(IKK)HMM predict
322Phosphoserine(ATM)HMM predict
322O-linkedHMM predict
411Phosphoserine(IKK)HMM predict
423Phosphothreonine(CK2)HMM predict
425Phosphoserine(IKK)HMM predict
431Phosphoserine(ATM)HMM predict
431Phosphoserine(IKK)HMM predict
435O-linkedHMM predict
441Phosphoserine(CDC2)HMM predict
441PhosphoserineHMM predict
493Phosphoserine(CK1)HMM predict
493Phosphoserine(IKK)HMM predict
495O-linkedHMM predict
496O-linkedHMM predict
497Phosphoserine(IKK)HMM predict
497O-linkedHMM predict
500Phosphoserine(CK1)HMM predict
501O-linkedHMM predict
502O-linkedHMM predict
504Phosphoserine(ATM)HMM predict
504O-linkedHMM predict
504Phosphoserine(IKK)HMM predict
506Phosphoserine(IKK)HMM predict
508Phosphoserine(IKK)HMM predict
510Phosphothreonine(PKC)HMM predict
515Phosphoserine(IKK)HMM predict
515Phosphoserine(PKG)HMM predict
515Phosphoserine(PKA)HMM predict
597Phosphoserine(IKK)HMM predict
604Phosphotyrosine(SRC)HMM predict
677Phosphoserine(CK1)HMM predict
688Phosphoserine(CK1)HMM predict
712Phosphoserine(CK2)HMM predict
719Phosphotyrosine(SRC)HMM predict
719Phosphotyrosine(EGFR)HMM predict
719Phosphotyrosine(INSR)HMM predict
719Phosphotyrosine(Syk)HMM predict
721PhosphoserineHMM predict
721Phosphoserine(CK1)HMM predict
727Phosphoserine(IKK)HMM predict
727O-linkedHMM predict
731Phosphoserine(ATM)HMM predict
826N-linkedHMM predict
836Phosphoserine(IKK)HMM predict
836Phosphoserine(CDC2)HMM predict
836O-linkedHMM predict
839Phosphoserine(MAPK)HMM predict
839Phosphoserine(CDC2)HMM predict
841O-linkedHMM predict
848Phosphothreonine(PKC)HMM predict
896Phosphoserine(CDK)HMM predict
896Phosphoserine(CDC2)HMM predict
1034Phosphotyrosine(INSR)HMM predict
1042Phosphoserine(IKK)HMM predict
1094Phosphotyrosine(Jak)HMM predict
1094Phosphotyrosine(Syk)HMM predict
1166O-linkedHMM predict
1167Phosphoserine(CK1)HMM predict
1168PhosphoserineHMM predict
1168Phosphoserine(CDC2)HMM predict
1168Phosphoserine(CDK)HMM predict
1168O-linkedHMM predict
1168Phosphoserine(ATM)HMM predict
1168Phosphoserine(IKK)HMM predict
1178Phosphoserine(CK1)HMM predict
1180Phosphoserine(ATM)HMM predict
1220Phosphoserine(IKK)HMM predict
1227O-linkedHMM predict
1227Phosphoserine(ATM)HMM predict
1240Phosphoserine(PKB)HMM predict
1240Phosphoserine(PKA)HMM predict
1240Phosphoserine(PKA)HMM predict
1240Phosphoserine(PKG)HMM predict
1251Phosphotyrosine(INSR)HMM predict
1251Phosphotyrosine(Syk)HMM predict
1274ThreonineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_022066
  • Location:chr17 71897490-71960882
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 71966128 71966520 392 5442
Gata2 K562GSE18868 71965786 71966670 884 5346
Rb GrowingGSE19898 71960910 71961144 234 145
hScc1 BcellGSE12603 71966202 71966520 318 5479
hScc1 CdLSGSE12603 71966128 71966557 429 5460
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 71905769 71906026 257 0
CTCF CD4GSE12889 71916206 71916584 378 0
CTCF CD4SISSRdata 71905769 71906026 257 0
CTCF CD4SISSRdata 71916206 71916584 378 0
CTCF G2GSE9613 71905813 71906749 936 0
CTCF G2GSE9613 71908009 71908273 264 0
CTCF G2GSE9613 71916192 71916611 419 0
CTCF G2GSE9613 71917386 71917692 306 0
CTCF G2GSE9613 71943331 71943615 284 0
Gata1 K562GSE18868 71913348 71914222 874 0
Gata2 K562GSE18868 71913167 71914225 1058 0
H3K4me2 HCT116GSE10453 71958612 71959986 1374 0
H3K4me3 colorectalcancer 71959535 71960015 480 0
H3ac HepG2E 71957791 71958264 473 0
H3ac HepG2E 71958612 71960015 1403 0
Myc K562GSE19551 71922303 71922671 368 0
Oct1 H2O2-HelaGSE14283 71955902 71955935 33 0
Oct1 HelaGSE14283 71955905 71955934 29 0
Sox2 hESGSE18292 71959433 71959675 242 0
TFAP2C MCF7GSE21234 71922052 71922521 469 0
TFAP2C MCF7GSE21234 71945424 71945808 384 0
hScc1 BcellGSE12603 71905392 71906293 901 0
hScc1 BcellGSE12603 71914884 71915205 321 0
hScc1 BcellGSE12603 71915933 71916611 678 0
hScc1 BcellGSE12603 71960274 71960687 413 0
hScc1 CdLSGSE12603 71905663 71906220 557 0
hScc1 CdLSGSE12603 71916192 71916611 419 0
p130 QuiescentGSE19898 71940463 71940720 257 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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