AutismKB 2.0

Annotation Detail for SDHB


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Basic Information Top
Gene Symbol:SDHB ( FLJ92337,IP,PGL4,SDH,SDH1,SDH2,SDHIP )
Gene Full Name: succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
Band: 1p36.13
Quick LinksEntrez ID:6390; OMIM: 185470; Uniprot ID:DHSB_HUMAN; ENSEMBL ID: ENSG00000117118; HGNC ID: 10681
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
92Phosphoserine(PKA)HMM predict
147Phosphotyrosine(Syk)HMM predict
163Phosphoserine(ATM)HMM predict
170Phosphotyrosine(EGFR)HMM predict
196S-palmitoylHMM predict
248N-linkedHMM predict
270MethionineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_003000
  • Location:chr1 17217813-17253251
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 17258824 17259043 219 5682
CTCF CD4SISSRdata 17258824 17259043 219 5682
CTCF HelaGSE12889 17258810 17259038 228 5673
CTCF G2GSE9613 17258403 17259560 1157 5730
ER Breast-CancerGSE22609 17255088 17255780 692 2183
ER MCF7GSE19013 17255192 17255695 503 2192
Myc K562GSE19551 17258671 17259010 339 5589
hScc1 BcellGSE12603 17258630 17259300 670 5714
hScc1 CdLSGSE12603 17258595 17259487 892 5790
hScc1 G2GSE9613 17258403 17259524 1121 5712
p130 shRbSenescentGSE19898 17258861 17259026 165 5692
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3ac HepG2E 17214481 17214728 247 3209
Nanog hESGSE18292 17214433 17214867 434 3164
hScc1 BcellGSE12603 17217278 17217492 214 429
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 17245205 17245566 361 0
CTCF CD4SISSRdata 17245205 17245566 361 0
CTCF G2GSE9613 17245147 17245417 270 0
CTCF G2GSE9613 17252800 17253206 406 0
ETS1 JurkatGSE17954 17252665 17253464 799 0
H3ac HepG2E 17251255 17252975 1720 0
NFkBII GM10847GSE19485 17252565 17253608 1043 0
P300 T30-glioblastomaGSE21026 17252478 17253478 1000 0
PHF8 293TGSE20725 17252492 17253565 1073 0
PHF8 Hs68plusFBSGSE20725 17252365 17253310 945 0
TFAP2C MCF7GSE21234 17229282 17229658 376 0
hScc1 BcellGSE12603 17245147 17245417 270 0
hScc1 CdLSGSE12603 17245147 17245417 270 0
hScc1 G2GSE9613 17245147 17245417 270 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-23b hsa-mir-23b 9 19490101
hsa-miR-23b* hsa-mir-23b 9 19490101
No data
Cis-Nats regulation Top

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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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