AutismKB 2.0

Annotation Detail for XPNPEP3


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Basic Information Top
Gene Symbol:XPNPEP3 ( APP3,NPHPL1 )
Gene Full Name: X-prolyl aminopeptidase (aminopeptidase P) 3, putative
Band: 22q13.2
Quick LinksEntrez ID:63929; OMIM: 613553; Uniprot ID:XPP3_HUMAN; ENSEMBL ID: ENSG00000196236; HGNC ID: 28052
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
32Phosphoserine(PKA)HMM predict
32Phosphoserine(PKG)HMM predict
64Phosphothreonine(MAPK)HMM predict
91Phosphoserine(IKK)HMM predict
102N-linkedHMM predict
106Phosphotyrosine(INSR)HMM predict
218Phosphotyrosine(Syk)HMM predict
248Phosphoserine(CDC2)HMM predict
308N-linkedHMM predict
311N-linkedHMM predict
385Phosphotyrosine(Syk)HMM predict
433Phosphothreonine(CDC2)HMM predict
455Phosphotyrosine(INSR)HMM predict
455SulfotyrosineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_022098
  • Location:chr22 39583039-39653823
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ETS1 JurkatGSE17954 39582069 39583692 1623 159
PHF8 HeLaGSE20725 39582006 39583677 1671 198
PHF8 Hs68plusFBSGSE20725 39581949 39584019 2070 56
p130 SenescentGSE19898 39582611 39583391 780 39
p130 shRbSenescentGSE19898 39582774 39582983 209 161
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 39625115 39625302 187 0
CTCF CD4GSE12889 39648726 39648962 236 0
CTCF CD4SISSRdata 39625115 39625302 187 0
CTCF CD4SISSRdata 39648726 39648962 236 0
H3K4me3 colorectalcancer 39583335 39584042 707 0
Nanog hESGSE18292 39624937 39625334 397 0
P300 T30-glioblastomaGSE21026 39646043 39647188 1145 0
SRF HelaGSE8489 39588109 39589584 1475 0
TAFII hESGSE17917 39625154 39625334 180 0
hScc1 BcellGSE12603 39624828 39625372 544 0
hScc1 CdLSGSE12603 39624610 39625372 762 0
hScc1 CdLSGSE12603 39648759 39648939 180 0
hScc1 G2GSE9613 39625115 39625372 257 0
p130 shRbQuiescentGSE19898 39583017 39583322 305 0
p63 keratinocytesGSE17611 39614786 39615766 980 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
17515 mRNA LOC63929 chr22 39577603 39583274 625 mRNA DNAJB7 chr22 39580052 39582630Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018