AutismKB 2.0

Annotation Detail for SELPLG


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Basic Information Top
Gene Symbol:SELPLG ( CD162,CLA,PSGL-1,PSGL1 )
Gene Full Name: selectin P ligand
Band: 12q24.11
Quick LinksEntrez ID:6404; OMIM: 600738; Uniprot ID:SELPL_HUMAN; ENSEMBL ID: ENSG00000110876; HGNC ID: 10722
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
42Pyrrolidone carboxylic acid.
46Sulfotyrosine.
48Sulfotyrosine.
51Sulfotyrosine.
57O-linked (GalNAc...).
65N-linked (GlcNAc...) (Potential).
111N-linked (GlcNAc...) (Potential).
302N-linked (GlcNAc...) (Potential).
389Phosphoserine.
393Phosphothreonine.
Location(AA) Modifications Resource
46Sulfotyrosine (Potential).Swiss-Prot 53.0
48Sulfotyrosine (Potential).Swiss-Prot 53.0
51Sulfotyrosine (Potential).Swiss-Prot 53.0
65N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
111N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
302N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
48SulfotyrosineHMM predict
48Phosphotyrosine(Jak)HMM predict
51SulfotyrosineHMM predict
65N-linkedHMM predict
70Phosphothreonine(MAPK)HMM predict
70O-linkedHMM predict
77Phosphothreonine(CDC2)HMM predict
77Phosphothreonine(CDK)HMM predict
77Phosphothreonine(MAPK)HMM predict
77O-linkedHMM predict
80O-linkedHMM predict
81O-linkedHMM predict
129O-linkedHMM predict
157O-linkedHMM predict
164O-linkedHMM predict
174O-linkedHMM predict
174PhosphothreonineHMM predict
187O-linkedHMM predict
214PhosphothreonineHMM predict
227O-linkedHMM predict
247O-linkedHMM predict
263O-linkedHMM predict
356N-linkedHMM predict
389Phosphoserine(CDC2)HMM predict
393PhosphothreonineHMM predict
393Phosphothreonine(MAPK)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_003006
  • Location:chr12 107539810-107551798
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 107553125 107553329 204 1429
NRSF pAbJurkat 107553125 107553387 262 1458
Pol2 GM12878GSE19551 107553515 107554633 1118 2276
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 107530045 107530295 250 9641
CTCF CD4GSE12889 107536104 107536425 321 3546
CTCF CD4SISSRdata 107530045 107530295 250 9641
CTCF CD4SISSRdata 107536104 107536425 321 3546
CTCF JurkatGSE12889 107530071 107530401 330 9575
CTCF G2GSE9613 107527386 107528403 1017 11916
CTCF G2GSE9613 107529690 107530005 315 9963
CTCF G2GSE9613 107531589 107531816 227 8108
CTCF G2GSE9613 107532377 107532985 608 7130
CTCF G2GSE9613 107534280 107534534 254 5404
CTCF G2GSE9613 107535264 107535436 172 4461
CTCF G2GSE9613 107536107 107536483 376 3516
ER Breast-CancerGSE22609 107535087 107535811 724 4362
NFkBII GM12878GSE19485 107530783 107532617 1834 8111
NFkBII GM12878GSE19485 107533573 107536566 2993 4741
NFkBII GM12892GSE19485 107534362 107536628 2266 4316
NFkBII GM15510GSE19485 107533776 107536626 2850 4610
NFkBII GM18526GSE19485 107533666 107536723 3057 4616
NRSF pAbJurkat 107534879 107535436 557 4653
RARG MCF7GSE15244 107529690 107530005 315 9963
hScc1 BcellGSE12603 107536107 107536455 348 3530
hScc1 CdLSGSE12603 107536107 107536590 483 3462
hScc1 G2GSE9613 107536107 107536868 761 3323
p130 SenescentGSE19898 107530024 107530328 304 9635
p130 shRbSenescentGSE19898 107527731 107528123 392 11884
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 107540139 107540419 280 0
CTCF G2GSE9613 107541357 107541883 526 0
CTCF G2GSE9613 107548054 107548326 272 0
CTCF G2GSE9613 107549594 107550032 438 0
CTCF G2GSE9613 107551430 107551606 176 0
NRSF pAbJurkat 107541478 107541843 365 0
Oct1 H2O2-HelaGSE14283 107551445 107551479 34 0
Oct1 HelaGSE14283 107551442 107551478 36 0
RARG MCF7GSE15244 107548190 107548680 490 0
STAT1 HeLaGSE12783 107544765 107550657 5892 0
TAF HelaGSE8489 107542895 107543044 149 0
TAF k562GSE8489 107546286 107547308 1022 0
TFAP2C MCF7GSE21234 107546041 107546826 785 0
TFAP2C MCF7GSE21234 107548303 107549033 730 0
hScc1 BcellGSE12603 107551430 107552159 729 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018