AutismKB 2.0

Annotation Detail for PRSS22


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Basic Information Top
Gene Symbol:PRSS22 ( BSSP-4,MGC9599,hBSSP-4 )
Gene Full Name: protease, serine, 22
Band: 16p13.3
Quick LinksEntrez ID:64063; OMIM: 609343; Uniprot ID:BSSP4_HUMAN; ENSEMBL ID: ENSG00000005001; HGNC ID: 14368
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
70N-linked (GlcNAc...).
Location(AA) Modifications Resource
70N-linked (GlcNAc...).Swiss-Prot 53.0
Location(AA) Modification Resource
57Phosphothreonine(CK2)HMM predict
70N-linkedHMM predict
81Phosphothreonine(PKC)HMM predict
118Phosphoserine(ATM)HMM predict
132Phosphotyrosine(SRC)HMM predict
194Phosphothreonine(CDK)HMM predict
295MethylarginineHMM predict
308Phosphoserine(ATM)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_022119
  • Location:chr16 2842728-2848171
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 2858303 2858730 427 10345
CTCF CD4SISSRdata 2858303 2858730 427 10345
CTCF HelaGSE12889 2858449 2858698 249 10402
CTCF JurkatGSE12889 2858478 2858790 312 10463
CTCF G2GSE9613 2848751 2849082 331 745
CTCF G2GSE9613 2858086 2858671 585 10207
ER MCF7GSE19013 2847700 2848734 1034 46
ETS1 JurkatGSE17954 2857780 2858939 1159 10188
GABP k562GSE8489 2855615 2856297 682 7785
GABP k562GSE8489 2857978 2858279 301 9957
NRSF JurkatGSE13047 2850772 2851823 1051 3126
NRSF JurkatSISSRdata 2850896 2851542 646 3048
NRSF mAbJurkat 2848751 2849082 331 745
NRSF mAbJurkat 2850405 2851403 998 2733
NRSF-mono JurkatQuESTdata 2850750 2851816 1066 3112
NRSF-poly JurkatQuESTdata 2850926 2851751 825 3167
Oct4 hESGSE17917 2856808 2857036 228 8751
P300 T0-glioblastomaGSE21026 2857665 2858808 1143 10065
PHF8 293TGSE20725 2857729 2858724 995 10055
PHF8 HeLaGSE20725 2857679 2858671 992 10004
TFAP2C MCF7GSE21234 2847489 2849275 1786 211
TFAP2C MCF7GSE21234 2857799 2858865 1066 10161
hScc1 BcellGSE12603 2858318 2858671 353 10323
hScc1 CdLSGSE12603 2857978 2858671 693 10153
hScc1 G2GSE9613 2858279 2858671 392 10304
p130 QuiescentGSE19898 2858051 2858370 319 10039
p130 SenescentGSE19898 2857795 2858321 526 9887
p130 shRbQuiescentGSE19898 2858052 2858532 480 10121
p130 shRbSenescentGSE19898 2857926 2858554 628 10069
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 2842205 2842382 177 435
GABP k562GSE8489 2839311 2839533 222 3307
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF JurkatGSE12889 2844851 2845016 165 0
CTCF G2GSE9613 2842937 2843619 682 0
CTCF G2GSE9613 2847303 2847900 597 0
hScc1 BcellGSE12603 2842937 2843261 324 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018