AutismKB 2.0

Annotation Detail for LRRC4


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Basic Information Top
Gene Symbol:LRRC4 ( MGC133342,MGC133343,NGL-2 )
Gene Full Name: leucine rich repeat containing 4
Band: 7q32.1
Quick LinksEntrez ID:64101; OMIM: 610486; Uniprot ID:LRRC4_HUMAN; ENSEMBL ID: ENSG00000128594; HGNC ID: 15586
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
277N-linked (GlcNAc...) (Potential).
322N-linked (GlcNAc...) (Potential).
363N-linked (GlcNAc...) (Potential).
388N-linked (GlcNAc...) (Potential).
410N-linked (GlcNAc...) (Potential).
434N-linked (GlcNAc...) (Potential).
440N-linked (GlcNAc...) (Potential).
447N-linked (GlcNAc...) (Potential).
450N-linked (GlcNAc...) (Potential).
Location(AA) Modifications Resource
277N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
322N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
363N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
388N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
410N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
434N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
440N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
447N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
450N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
172Phosphoserine(PKA)HMM predict
186Phosphotyrosine(INSR)HMM predict
213N-linkedHMM predict
277N-linkedHMM predict
322N-linkedHMM predict
329S-palmitoylHMM predict
376PhosphothreonineHMM predict
388N-linkedHMM predict
422Phosphotyrosine(INSR)HMM predict
422Phosphotyrosine(Jak)HMM predict
440N-linkedHMM predict
447N-linkedHMM predict
450N-linkedHMM predict
452O-linkedHMM predict
456O-linkedHMM predict
458O-linkedHMM predict
479O-linkedHMM predict
480O-linkedHMM predict
483Phosphotyrosine(INSR)HMM predict
483Phosphotyrosine(Jak)HMM predict
488O-linkedHMM predict
489O-linkedHMM predict
491O-linkedHMM predict
492O-linkedHMM predict
565Phosphothreonine(PKC)HMM predict
579O-linkedHMM predict
580Phosphoserine(IKK)HMM predict
584O-linkedHMM predict
632O-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_022143
  • Location:chr7 127454361-127458237
  • strand:-
No data
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 127457883 127458055 172 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
24597 mRNA SND1 chr7 126886184 127326609 3877 mRNA LRRC4 chr7 127261076 127264953 Non-exonic Bidirectional (NOB) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018