AutismKB 2.0

Annotation Detail for IFIH1


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Basic Information Top
Gene Symbol:IFIH1 ( Hlcd,IDDM19,MDA-5,MDA5,MGC133047 )
Gene Full Name: interferon induced with helicase C domain 1
Band: 2q24.2
Quick LinksEntrez ID:64135; OMIM: 606951; Uniprot ID:IFIH1_HUMAN; ENSEMBL ID: ENSG00000115267; HGNC ID: 18873
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
289Phosphoserine (By similarity).
301Phosphoserine (By similarity).
645Phosphoserine (By similarity).
Location(AA) Modifications Resource
301Phosphoserine (By similarity).Swiss-Prot 53.0
645Phosphoserine (By similarity).Swiss-Prot 53.0
Location(AA) Modification Resource
6Phosphoserine(CK2)HMM predict
25Phosphotyrosine(Jak)HMM predict
34Phosphotyrosine(Jak)HMM predict
88Phosphoserine(CDC2)HMM predict
114Phosphotyrosine(Jak)HMM predict
160N-linkedHMM predict
205Phosphoserine(CK2)HMM predict
211N-linkedHMM predict
213Phosphoserine(ATM)HMM predict
242N-linkedHMM predict
243N-linkedHMM predict
248Phosphoserine(CK2)HMM predict
248Phosphoserine(IKK)HMM predict
261Phosphoserine(CK1)HMM predict
291Phosphoserine(CK2)HMM predict
301Phosphoserine(MAPK)HMM predict
301Phosphoserine(CDK)HMM predict
614N-linkedHMM predict
623SulfotyrosineHMM predict
630Phosphotyrosine(Syk)HMM predict
653Phosphotyrosine(INSR)HMM predict
696Phosphotyrosine(INSR)HMM predict
696Phosphotyrosine(SRC)HMM predict
830Phosphotyrosine(SRC)HMM predict
899N-linkedHMM predict
909N-linkedHMM predict
930N-linkedHMM predict
932Phosphothreonine(CDC2)HMM predict
981S-palmitoylHMM predict
994N-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_022168
  • Location:chr2 162831835-162883284
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ER E2-MCF7GSE14664 162894582 162894668 86 11341
H3ac HepG2E 162883512 162884154 642 549
NFkBII GM12878GSE19485 162882297 162885685 3388 707
NFkBII GM15510GSE19485 162882397 162884899 2502 364
NFkBII GM18505GSE19485 162882277 162884408 2131 58
NFkBII GM18526GSE19485 162882305 162885209 2904 473
PHF8 Hs68plusFBSGSE20725 162883082 162884070 988 292
Rb SenescentGSE19898 162883328 162883784 456 272
Rb shRbSenescenceGSE19898 162883512 162883855 343 399
p130 QuiescentGSE19898 162883460 162883909 449 400
p130 SenescentGSE19898 162883448 162883840 392 360
p130 shRbSenescentGSE19898 162883352 162883916 564 350
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ER Fulvestrant-MCF7GSE14664 162825699 162825733 34 6120
Oct1 H2O2-HelaGSE14283 162824902 162824931 29 6919
Oct1 HelaGSE14283 162825702 162825735 33 6117
Oct1 HelaGSE14283 162826789 162826817 28 5033
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 162862712 162863113 401 0
CTCF CD4GSE12889 162865948 162866328 380 0
CTCF CD4SISSRdata 162862712 162863113 401 0
CTCF CD4SISSRdata 162865948 162866328 380 0
CTCF G2GSE9613 162865953 162866299 346 0
H3K4me3 colorectalcancer 162881174 162881741 567 0
NFkBII GM12892GSE19485 162880913 162884643 3730 0
Oct1 H2O2-HelaGSE14283 162883173 162883204 31 0
Oct1 HelaGSE14283 162838426 162838457 31 0
Oct1 HelaGSE14283 162842241 162842267 26 0
Oct1 HelaGSE14283 162864281 162864320 39 0
Oct1 HelaGSE14283 162883168 162883203 35 0
RNAII Tamoxifen-MCF7GSE14664 162864284 162864325 41 0
hScc1 BcellGSE12603 162865953 162866187 234 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
15202 EST chr2 163000481 163034405 65 mRNA IFIH1 chr2 162949096 163000546 Non-exonic Bidirectional (NOB) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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