AutismKB 2.0

Annotation Detail for SFPQ


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:SFPQ ( POMP100,PSF )
Gene Full Name: splicing factor proline/glutamine-rich
Band: 1p34.3
Quick LinksEntrez ID:6421; OMIM: 605199; Uniprot ID:SFPQ_HUMAN; ENSEMBL ID: ENSG00000116560; HGNC ID: 10774
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
7Omega-N-methylated arginine.
9Omega-N-methylated arginine.
19Omega-N-methylated arginine.
25Omega-N-methylated arginine.
33Phosphoserine.
273Phosphoserine.
283Phosphoserine.
314N6,N6-dimethyllysine.
319N6-acetyllysine.
338N6-acetyllysine.
379Phosphoserine.
421N6-acetyllysine.
472N6-acetyllysine.
571Dimethylated arginine.
681Omega-N-methylarginine.
687Phosphothreonine.
693Dimethylated arginine.
Location(AA) Modifications Resource
7Omega-N-methylated arginine.Swiss-Prot 53.0
9Omega-N-methylated arginine.Swiss-Prot 53.0
19Omega-N-methylated arginine.Swiss-Prot 53.0
25Omega-N-methylated arginine.Swiss-Prot 53.0
33Phosphoserine.Swiss-Prot 53.0
33PhosphoserinePhospho.ELM 6.0
Location(AA) Modification Resource
9MethylarginineHMM predict
25MethylarginineHMM predict
107O-linkedHMM predict
128O-linkedHMM predict
128O-linkedHMM predict
128O-linkedHMM predict
129O-linkedHMM predict
130O-linkedHMM predict
130O-linkedHMM predict
135Phosphothreonine(MAPK)HMM predict
135O-linkedHMM predict
138O-linkedHMM predict
139O-linkedHMM predict
145O-linkedHMM predict
150O-linkedHMM predict
150O-linkedHMM predict
152O-linkedHMM predict
158O-linkedHMM predict
159O-linkedHMM predict
168Phosphothreonine(MAPK)HMM predict
168O-linkedHMM predict
168Phosphothreonine(CDK)HMM predict
171O-linkedHMM predict
172O-linkedHMM predict
172O-linkedHMM predict
176O-linkedHMM predict
177Phosphothreonine(CDC2)HMM predict
177Phosphothreonine(MAPK)HMM predict
177Phosphothreonine(CDK)HMM predict
225O-linkedHMM predict
242MethylarginineHMM predict
273Phosphoserine(CK1)HMM predict
273Phosphoserine(CK2)HMM predict
355Phosphothreonine(CDC2)HMM predict
379Phosphoserine(CDC2)HMM predict
392Phosphoserine(ATM)HMM predict
441Phosphothreonine(CDC2)HMM predict
476Phosphothreonine(MAPK)HMM predict
491Phosphoserine(ATM)HMM predict
597Phosphotyrosine(SRC)HMM predict
602Phosphotyrosine(INSR)HMM predict
602Phosphotyrosine(Syk)HMM predict
681MethylarginineHMM predict
691TyrosineHMM predict
693MethylarginineHMM predict
695ArginineHMM predict
698Phosphotyrosine(INSR)HMM predict
698Phosphotyrosine(Syk)HMM predict
707PhenylalanineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_005066
  • Location:chr1 35421789-35431321
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 35440347 35440633 286 9169
CTCF CD4SISSRdata 35440347 35440633 286 9169
CTCF G2GSE9613 35440310 35440632 322 9150
Fos K562GSE19551 35431159 35431977 818 247
H3ac HepG2E 35431291 35431992 701 320
LIN9 G0GSE7516 35431025 35431992 967 187
LIN9 SGSE7516 35431025 35431992 967 187
Myc K562GSE19551 35440271 35440730 459 9179
Nanog hESGSE18292 35448137 35448370 233 16932
P300 T30-glioblastomaGSE21026 35430883 35432100 1217 170
Pol2 GM12878GSE19551 35431027 35431816 789 100
TAF HelaGSE8489 35431712 35431992 280 531
TAF k562GSE8489 35431255 35431992 737 302
TFAP2C MCF7GSE21234 35437220 35437555 335 6066
hScc1 BcellGSE12603 35440275 35440632 357 9132
hScc1 CdLSGSE12603 35440166 35440705 539 9114
p130 SenescentGSE19898 35431065 35431855 790 139
p130 shRbSenescentGSE19898 35431001 35431782 781 70
p130 G0GSE7516 35431025 35431992 967 187
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 35429964 35431255 1291 0
H3K4me2 HCT116GSE10453 35428896 35429498 602 0
H3K4me3 colorectalcancer 35428896 35430397 1501 0
H3ac HepG2E 35427174 35427829 655 0
H3ac HepG2E 35428515 35430131 1616 0
P300 T0-glioblastomaGSE21026 35430724 35431880 1156 0
PHF8 293TGSE20725 35430730 35431753 1023 0
PHF8 HeLaGSE20725 35429974 35432051 2077 0
PHF8 Hs68minusFBSGSE20725 35430924 35431569 645 0
PHF8 Hs68plusFBSGSE20725 35429828 35431830 2002 0
PolII HeLaGSE12783 35428576 35432351 3775 0
TAF k562GSE8489 35428442 35430131 1689 0
USF1 HepG2E 35427174 35427829 655 0
hScc1 BcellGSE12603 35429964 35430695 731 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018