AutismKB 2.0

Annotation Detail for SFRP1


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Basic Information Top
Gene Symbol:SFRP1 ( FRP,FRP-1,FRP1,FrzA,SARP2 )
Gene Full Name: secreted frizzled-related protein 1
Band: 8p11.21
Quick LinksEntrez ID:6422; OMIM: 604156; Uniprot ID:SFRP1_HUMAN; ENSEMBL ID: ENSG00000104332; HGNC ID: 10776
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
173N-linked (GlcNAc...).
Location(AA) Modifications Resource
173N-linked (GlcNAc...).Swiss-Prot 53.0
Location(AA) Modification Resource
11MethylarginineHMM predict
36SulfotyrosineHMM predict
48Phosphoserine(CDK)HMM predict
109Phosphothreonine(PKA)HMM predict
173N-linkedHMM predict
175O-linkedHMM predict
175O-linkedHMM predict
298MethionineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_003012
  • Location:chr8 41238635-41286136
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 41286773 41287341 568 921
CTCF G2GSE9613 41288066 41288357 291 2075
CTCF G2GSE9613 41300862 41301217 355 14903
CTCF G2GSE9613 41303938 41304083 145 17874
FOXA1 MCF7GSE15244 41299798 41301145 1347 14335
H3K27me3 colorectalcancer 41286262 41286474 212 232
H3K27me3 colorectalcancer 41287373 41288950 1577 2025
Stat6 IL-4-hr4GSE17850 41288366 41288919 553 2506
TFAP2C MCF7GSE21234 41299939 41300538 599 14102
hScc1 BcellGSE12603 41293106 41293251 145 7042
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 41224451 41224758 307 14031
CTCF G2GSE9613 41235968 41236096 128 2604
Rb GrowingGSE19898 41221298 41221536 238 17219
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 41260807 41261656 849 0
CTCF G2GSE9613 41267179 41267484 305 0
CTCF G2GSE9613 41279228 41280164 936 0
CTCF G2GSE9613 41285282 41286289 1007 0
ER E2-MCF7GSE14664 41250821 41250861 40 0
FOXA1 MCF7GSE15244 41272787 41273136 349 0
FOXA1 MCF7GSE15244 41279946 41280200 254 0
Fos K562GSE19551 41254159 41254526 367 0
NRSF pAbJurkat 41285621 41286223 602 0
RARG MCF7GSE15244 41279946 41280281 335 0
Stat6 IL-4-hr1GSE17850 41278743 41279293 550 0
Stat6 IL-4-hr4GSE17850 41253912 41254378 466 0
hScc1 BcellGSE12603 41265435 41265618 183 0
hScc1 BcellGSE12603 41279192 41280281 1089 0
hScc1 BcellGSE12603 41285104 41286116 1012 0
hScc1 CdLSGSE12603 41240893 41241332 439 0
hScc1 CdLSGSE12603 41279373 41280320 947 0
hScc1 CdLSGSE12603 41285657 41286035 378 0
hScc1 G2GSE9613 41279292 41280392 1100 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-141 hsa-mir-141 12 20420713
hsa-miR-141 hsa-mir-141 12 18698484
hsa-miR-141* hsa-mir-141 12 20420713
hsa-miR-141* hsa-mir-141 12 18698484
hsa-miR-142-3p hsa-mir-142 17 20420713
hsa-miR-149 hsa-mir-149 2 20420713
hsa-miR-149* hsa-mir-149 2 20420713
hsa-miR-185 hsa-mir-185 22 20420713
hsa-miR-185* hsa-mir-185 22 20420713
hsa-miR-200a hsa-mir-200a 1 18698484
hsa-miR-200a* hsa-mir-200a 1 20420713
hsa-miR-200a* hsa-mir-200a 1 18698484
hsa-miR-200b hsa-mir-200b 1 18698484
hsa-miR-200b* hsa-mir-200b 1 18698484
hsa-miR-200c hsa-mir-200c 12 20420713
hsa-miR-200c hsa-mir-200c 12 18698484
hsa-miR-200c* hsa-mir-200c 12 20420713
hsa-miR-200c* hsa-mir-200c 12 18698484
hsa-miR-205 hsa-mir-205 1 18698484
hsa-miR-21 hsa-mir-21 17 20420713
hsa-miR-21* hsa-mir-21 17 20420713
hsa-miR-224 hsa-mir-224 X 20420713
hsa-miR-31 hsa-mir-31 9 21048943
hsa-miR-31* hsa-mir-31 9 21048943
hsa-miR-34a hsa-mir-34a 1 20420713
hsa-miR-34a* hsa-mir-34a 1 20420713
hsa-miR-429 hsa-mir-429 1 18698484
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018