AutismKB 2.0

Annotation Detail for ROBO3


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Basic Information Top
Gene Symbol:ROBO3 ( FLJ21044,HGPPS,HGPS,RBIG1,RIG1 )
Gene Full Name: roundabout, axon guidance receptor, homolog 3 (Drosophila)
Band: 11q24.2
Quick LinksEntrez ID:64221; OMIM: 608630; Uniprot ID:ROBO3_HUMAN; ENSEMBL ID: ENSG00000154134; HGNC ID: 13433
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
25N-linked (GlcNAc...) (Potential).
34N-linked (GlcNAc...) (Potential).
41N-linked (GlcNAc...) (Potential).
53N-linked (GlcNAc...) (Potential).
156N-linked (GlcNAc...) (Potential).
410N-linked (GlcNAc...) (Potential).
459N-linked (GlcNAc...) (Potential).
503N-linked (GlcNAc...) (Potential).
784N-linked (GlcNAc...) (Potential).
813N-linked (GlcNAc...) (Potential).
820N-linked (GlcNAc...) (Potential).
1263Phosphoserine.
Location(AA) Modifications Resource
25N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
34N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
41N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
53N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
156N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
410N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
459N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
503N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
784N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
813N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
820N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
25N-linkedHMM predict
34N-linkedHMM predict
41N-linkedHMM predict
53N-linkedHMM predict
106Phosphothreonine(PKC)HMM predict
158Phosphoserine(PKG)HMM predict
197Phosphoserine(CK1)HMM predict
259Phosphoserine(PKA)HMM predict
324Phosphotyrosine(INSR)HMM predict
342Phosphoserine(ATM)HMM predict
404Phosphoserine(CDC2)HMM predict
410N-linkedHMM predict
422Phosphotyrosine(Jak)HMM predict
459N-linkedHMM predict
503N-linkedHMM predict
545Phosphoserine(CDC2)HMM predict
553O-linkedHMM predict
554O-linkedHMM predict
554Phosphoserine(CDC2)HMM predict
560O-linkedHMM predict
625Phosphotyrosine(Jak)HMM predict
649Phosphothreonine(PKC)HMM predict
653Phosphoserine(CDC2)HMM predict
653PhosphoserineHMM predict
723Phosphoserine(IKK)HMM predict
725Phosphoserine(ATM)HMM predict
725Phosphoserine(IKK)HMM predict
758Phosphoserine(CK1)HMM predict
769O-linkedHMM predict
784N-linkedHMM predict
813N-linkedHMM predict
820N-linkedHMM predict
909S-palmitoylHMM predict
932O-linkedHMM predict
944Phosphoserine(ATM)HMM predict
947O-linkedHMM predict
960Phosphoserine(IKK)HMM predict
970O-linkedHMM predict
972Phosphoserine(CDK)HMM predict
974Phosphoserine(IKK)HMM predict
974PhosphoserineHMM predict
993Phosphotyrosine(Syk)HMM predict
994Phosphotyrosine(Syk)HMM predict
1019Phosphotyrosine(INSR)HMM predict
1019Phosphotyrosine(Abl)HMM predict
1047C-linkedHMM predict
1050Phosphotyrosine(Syk)HMM predict
1107Phosphoserine(CK2)HMM predict
1108Phosphoserine(CK2)HMM predict
1129O-linkedHMM predict
1135Phosphothreonine(CDC2)HMM predict
1135Phosphothreonine(MAPK)HMM predict
1135Phosphothreonine(CDK)HMM predict
1141O-linkedHMM predict
1141Phosphothreonine(MAPK)HMM predict
1141Phosphothreonine(CDK)HMM predict
1143O-linkedHMM predict
1143Phosphoserine(CDC2)HMM predict
1143Phosphoserine(MAPK)HMM predict
1143Phosphoserine(CDK)HMM predict
1143Phosphoserine(IKK)HMM predict
1145O-linkedHMM predict
1152O-linkedHMM predict
1153O-linkedHMM predict
1155O-linkedHMM predict
1157O-linkedHMM predict
1157Phosphothreonine(MAPK)HMM predict
1157Phosphothreonine(CDK)HMM predict
1159O-linkedHMM predict
1159Phosphoserine(CDC2)HMM predict
1159Phosphoserine(ATM)HMM predict
1159Phosphoserine(IKK)HMM predict
1186O-linkedHMM predict
1186Phosphoserine(CDC2)HMM predict
1186Phosphoserine(MAPK)HMM predict
1189Phosphoserine(ATM)HMM predict
1189Phosphoserine(IKK)HMM predict
1216O-linkedHMM predict
1216Phosphoserine(CDC2)HMM predict
1216Phosphoserine(CDK)HMM predict
1216Phosphoserine(ATM)HMM predict
1216PhosphoserineHMM predict
1218O-linkedHMM predict
1218Phosphoserine(CDC2)HMM predict
1218Phosphoserine(ATM)HMM predict
1222O-linkedHMM predict
1223O-linkedHMM predict
1225O-linkedHMM predict
1226O-linkedHMM predict
1246MethylarginineHMM predict
1290Phosphoserine(IKK)HMM predict
1299Phosphoserine(CK1)HMM predict
1338O-linkedHMM predict
1339Phosphoserine(IKK)HMM predict
1340O-linkedHMM predict
1343O-linkedHMM predict
1347N-linkedHMM predict
1354Phosphoserine(CDC2)HMM predict
1356MethylarginineHMM predict
1368Phosphoserine(CK1)HMM predict
1368Phosphoserine(ATM)HMM predict
1368Phosphoserine(IKK)HMM predict
1370Phosphoserine(IKK)HMM predict
1372Phosphoserine(ATM)HMM predict
1372Phosphoserine(IKK)HMM predict
1374Phosphoserine(ATM)HMM predict
1380LysineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_022370
  • Location:chr11 124240491-124256570
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ER MCF7GSE19013 124239663 124240252 589 534
H3K27me3 colorectalcancer 124236115 124236351 236 4259
H3K27me3 colorectalcancer 124236868 124238853 1985 2631
H3K27me3 colorectalcancer 124239279 124240608 1329 548
NRSF JurkatGSE13047 124238624 124239391 767 1484
NRSF mAbJurkat 124236868 124238897 2029 2609
NRSF-mono JurkatQuESTdata 124238412 124239483 1071 1544
NRSF-poly JurkatQuESTdata 124238783 124239391 608 1405
TAF HelaGSE8489 124229020 124229579 559 11192
USF1 HepG2E 124236981 124239168 2187 2417
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 124251426 124251854 428 0
CTCF CD4SISSRdata 124251426 124251854 428 0
H3K27me3 colorectalcancer 124241879 124242906 1027 0
NRSF pAbJurkat 124251149 124251635 486 0
PHF8 Hs68minusFBSGSE20725 124251216 124252216 1000 0
hScc1 BcellGSE12603 124242649 124243149 500 0
hScc1 CdLSGSE12603 124242325 124243259 934 0
hScc1 G2GSE9613 124242325 124243259 934 0
hScc1 G2GSE9613 124251000 124251843 843 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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