AutismKB 2.0

Annotation Detail for RFWD2


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Basic Information Top
Gene Symbol:RFWD2 ( COP1,FLJ10416,RNF200 )
Gene Full Name: ring finger and WD repeat domain 2
Band: 1q25.1-q25.2
Quick LinksEntrez ID:64326; OMIM: 608067; Uniprot ID:RFWD2_HUMAN; ENSEMBL ID: ENSG00000143207; HGNC ID: 17440
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
113Nuclear localization signal 1.
206Nuclear localization signal 2.
245Nuclear export signal (By similarity).
Location(AA) Modifications Resource
Location(AA) Modification Resource
15O-linkedHMM predict
15Phosphoserine(CDC2)HMM predict
15Phosphoserine(IKK)HMM predict
18Phosphoserine(IKK)HMM predict
19O-linkedHMM predict
22O-linkedHMM predict
25O-linkedHMM predict
26O-linkedHMM predict
28Phosphoserine(CK2)HMM predict
30Phosphoserine(IKK)HMM predict
33Phosphoserine(CK1)HMM predict
34Phosphoserine(IKK)HMM predict
34Phosphoserine(CDC2)HMM predict
34Phosphoserine(CDK)HMM predict
34Phosphoserine(ATM)HMM predict
36Phosphoserine(IKK)HMM predict
36O-linkedHMM predict
43O-linkedHMM predict
75O-linkedHMM predict
156S-palmitoylHMM predict
210Phosphoserine(IKK)HMM predict
213Phosphoserine(CK1)HMM predict
287Phosphoserine(CK1)HMM predict
304Phosphoserine(MAPK)HMM predict
307O-linkedHMM predict
319PhosphoserineHMM predict
319Phosphoserine(ATM)HMM predict
319O-linkedHMM predict
319Phosphoserine(CDK)HMM predict
319Phosphoserine(CDC2)HMM predict
328PhosphoserineHMM predict
331Phosphotyrosine(Syk)HMM predict
331Phosphotyrosine(Abl)HMM predict
331Phosphotyrosine(SRC)HMM predict
331Phosphotyrosine(Jak)HMM predict
332Phosphoserine(ATM)HMM predict
338O-linkedHMM predict
340Phosphoserine(CDK)HMM predict
341Phosphoserine(ATM)HMM predict
343Phosphothreonine(PKC)HMM predict
350N-linkedHMM predict
361Phosphothreonine(PKA)HMM predict
373Phosphoserine(CDK)HMM predict
387Phosphoserine(IKK)HMM predict
387Phosphoserine(CAMK2)HMM predict
387Phosphoserine(ATM)HMM predict
419N-linkedHMM predict
509Phosphotyrosine(EGFR)HMM predict
618Phosphothreonine(CK2)HMM predict
632S-palmitoylHMM predict
654Phosphotyrosine(INSR)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001001740
  • Location:chr1 174180590-174442992
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 174453352 174453526 174 10447
ETS1 JurkatGSE17954 174442113 174443951 1838 40
Nanog hESGSE18292 174460917 174461152 235 18042
Oct1 HelaGSE14283 174460874 174460908 34 17899
PHF8 293TGSE20725 174442381 174443902 1521 149
RARA MCF7GSE15244 174443507 174443890 383 706
TAF k562GSE8489 174443432 174443890 458 669
p130 QuiescentGSE19898 174442945 174443547 602 254
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Nanog hESGSE18292 174171911 174172106 195 8582
Oct1 HelaGSE14283 174168178 174168251 73 12376
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 174355463 174355612 149 0
CTCF CD4SISSRdata 174355463 174355612 149 0
CTCF G2GSE9613 174309312 174309659 347 0
CTCF G2GSE9613 174442688 174443133 445 0
ER E2-MCF7GSE14664 174187363 174187496 133 0
ER E2-MCF7GSE14664 174195713 174195745 32 0
ER E2-MCF7GSE14664 174247403 174247440 37 0
ER E2-MCF7GSE14664 174422516 174422548 32 0
ER Fulvestrant-MCF7GSE14664 174187364 174187503 139 0
ER Fulvestrant-MCF7GSE14664 174348874 174348928 54 0
GABP k562GSE8489 174373467 174373599 132 0
H3K4me2 HCT116GSE10453 174441168 174442163 995 0
H3K4me3 colorectalcancer 174440738 174442163 1425 0
H3ac HepG2E 174440738 174442342 1604 0
NRSF JurkatGSE13047 174337857 174338530 673 0
NRSF mAbJurkat 174339518 174340051 533 0
NRSF-mono JurkatQuESTdata 174337856 174338441 585 0
NRSF-poly JurkatQuESTdata 174337925 174338393 468 0
Nanog hESGSE18292 174355457 174355793 336 0
Oct1 H2O2-HelaGSE14283 174232560 174232589 29 0
Oct1 H2O2-HelaGSE14283 174247410 174247441 31 0
Oct1 H2O2-HelaGSE14283 174338295 174338324 29 0
Oct1 H2O2-HelaGSE14283 174416708 174416743 35 0
Oct1 HelaGSE14283 174184661 174184731 70 0
Oct1 HelaGSE14283 174223044 174223075 31 0
Oct1 HelaGSE14283 174247404 174247443 39 0
Oct1 HelaGSE14283 174284367 174284404 37 0
Oct1 HelaGSE14283 174284448 174284498 50 0
Oct1 HelaGSE14283 174290110 174290143 33 0
Oct1 HelaGSE14283 174301518 174301555 37 0
Oct1 HelaGSE14283 174308293 174308332 39 0
Oct1 HelaGSE14283 174312356 174312385 29 0
Oct1 HelaGSE14283 174331591 174331619 28 0
Oct1 HelaGSE14283 174348875 174348975 100 0
Oct1 HelaGSE14283 174416709 174416748 39 0
TAF HelaGSE8489 174441279 174442198 919 0
TAF k562GSE8489 174440738 174442270 1532 0
hScc1 BcellGSE12603 174309348 174309683 335 0
hScc1 CdLSGSE12603 174309199 174309683 484 0
p63 keratinocytesGSE17611 174282529 174283276 747 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
1971 EST chr1 172907446 172907925 479 mRNA RFWD2 chr1 172645624 172908027Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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