AutismKB 2.0

Annotation Detail for TRA2B


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Basic Information Top
Gene Symbol:TRA2B ( DKFZp686F18120,Htra2-beta,SFRS10,SRFS10,TRA2-BETA,TRAN2B )
Gene Full Name: transformer 2 beta homolog (Drosophila)
Band: 3q27.2
Quick LinksEntrez ID:6434; OMIM: 602719; Uniprot ID:TRA2B_HUMAN; ENSEMBL ID: ENSG00000136527; HGNC ID: 10781
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
2Phosphoserine.
4Phosphoserine (By similarity).
14Phosphoserine.
29Phosphoserine.
33Phosphothreonine.
37Phosphoserine.
39Phosphoserine.
50Phosphoserine (By similarity).
52Phosphoserine (By similarity).
54Phosphoserine (By similarity).
56Phosphoserine (By similarity).
69Phosphothreonine.
71Phosphoserine.
83Phosphoserine.
85Phosphoserine.
87Phosphoserine.
95Phosphoserine.
97Phosphoserine.
99Phosphoserine.
201Phosphothreonine.
207Phosphotyrosine.
212Phosphothreonine.
215Phosphoserine.
216Phosphoserine.
241Dimethylated arginine.
264Phosphoserine.
266Phosphoserine.
268Phosphotyrosine.
269Phosphotyrosine.
276Phosphoserine.
280Phosphoserine (By similarity).
282Phosphoserine (By similarity).
284Phosphoserine (By similarity).
Location(AA) Modifications Resource
2Phosphoserine.Swiss-Prot 53.0
2PhosphoserinePhospho.ELM 6.0
14PhosphoserinePhospho.ELM 6.0
29PhosphoserinePhospho.ELM 6.0
29Phosphoserine.Swiss-Prot 53.0
33Phosphothreonine.Swiss-Prot 53.0
33PhosphothreoninePhospho.ELM 6.0
37Phosphoserine.Swiss-Prot 53.0
37PhosphoserinePhospho.ELM 6.0
39Phosphoserine.Swiss-Prot 53.0
39PhosphoserinePhospho.ELM 6.0
69PhosphothreoninePhospho.ELM 6.0
69Phosphothreonine.Swiss-Prot 53.0
71Phosphoserine.Swiss-Prot 53.0
71PhosphoserinePhospho.ELM 6.0
95Phosphoserine.Swiss-Prot 53.0
95PhosphoserinePhospho.ELM 6.0
97PhosphoserinePhospho.ELM 6.0
97Phosphoserine.Swiss-Prot 53.0
99PhosphoserinePhospho.ELM 6.0
99Phosphoserine.Swiss-Prot 53.0
201PhosphothreoninePhospho.ELM 6.0
201Phosphothreonine (By similarity).Swiss-Prot 53.0
203PhosphothreoninePhospho.ELM 6.0
241Omega-N-methylated arginine.Swiss-Prot 53.0
264PhosphoserinePhospho.ELM 6.0
264Phosphoserine.Swiss-Prot 53.0
266Phosphoserine.Swiss-Prot 53.0
266PhosphoserinePhospho.ELM 6.0
276PhosphoserinePhospho.ELM 6.0
276Phosphoserine.Swiss-Prot 53.0
280Phosphoserine (By similarity).Swiss-Prot 53.0
282Phosphoserine (By similarity).Swiss-Prot 53.0
284Phosphoserine (By similarity).Swiss-Prot 53.0
Location(AA) Modification Resource
9Phosphotyrosine(Syk)HMM predict
9Phosphotyrosine(EGFR)HMM predict
18Phosphoserine(IKK)HMM predict
20Phosphoserine(ATM)HMM predict
22Phosphoserine(IKK)HMM predict
33Phosphothreonine(CDC2)HMM predict
33Phosphothreonine(MAPK)HMM predict
33Phosphothreonine(CDK)HMM predict
39Phosphoserine(PKB)HMM predict
39Phosphoserine(IKK)HMM predict
39Phosphoserine(CK1)HMM predict
48Phosphoserine(CK1)HMM predict
54Phosphoserine(CK1)HMM predict
54Phosphoserine(IKK)HMM predict
64Phosphoserine(PKG)HMM predict
73PhosphoserineHMM predict
95Phosphoserine(PKG)HMM predict
99Phosphoserine(IKK)HMM predict
103Phosphothreonine(PKC)HMM predict
201Phosphothreonine(MAPK)HMM predict
215Phosphoserine(CDC2)HMM predict
221Phosphotyrosine(Syk)HMM predict
222SulfotyrosineHMM predict
226Phosphotyrosine(INSR)HMM predict
230Phosphotyrosine(Syk)HMM predict
235Phosphotyrosine(Syk)HMM predict
241MethylarginineHMM predict
264Phosphoserine(PKG)HMM predict
266Phosphoserine(CDC2)HMM predict
268Phosphotyrosine(Syk)HMM predict
271MethylarginineHMM predict
274TyrosineHMM predict
288TyrosineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_004593
  • Location:chr3 187117235-187138449
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 187144060 187144300 240 5731
CTCF CD4SISSRdata 187144060 187144300 240 5731
FOXA1 MCF7GSE15244 187141527 187141768 241 3198
FoxA1 MCF7MACSdata 187141510 187141768 258 3190
H3ac HepG2E 187154066 187154388 322 15778
Myc K562GSE19551 187143917 187144233 316 5626
Rb GrowingGSE19898 187138440 187138896 456 219
Rb QuiescentGSE19898 187138139 187138973 834 107
Rb SenescentGSE19898 187138310 187138856 546 134
Rb SenescentGSE19898 187144020 187144255 235 5688
Rb shRbQuiescentGSE19898 187138288 187138801 513 95
Rb shRbSenescenceGSE19898 187138436 187138916 480 227
USF1 HepG2E 187150002 187150253 251 11678
USF1 HepG2E 187154066 187154388 322 15778
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 187100843 187101092 249 16268
CTCF G2GSE9613 187111054 187111427 373 5995
Fos K562GSE19551 187100596 187101148 552 16364
Myc K562GSE19551 187107862 187108203 341 9203
P300 T30-glioblastomaGSE21026 187100457 187101111 654 16452
STAT1 IFNSISSRdata 187107589 187108219 630 9332
VDR GM10861-stimGSE22484 187110999 187118198 7199 2637
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 187129876 187130058 182 0
CTCF G2GSE9613 187137483 187138950 1467 0
H3K4me3 colorectalcancer 187136274 187138260 1986 0
H3ac HepG2E 187134206 187138925 4719 0
NRSF mAbJurkat 187134868 187138334 3466 0
PHF8 293TGSE20725 187137856 187138831 975 0
PHF8 HeLaGSE20725 187137331 187138974 1643 0
Pol2 GM12878GSE19551 187137533 187138930 1397 0
PolII HeLaGSE12783 187134479 187139085 4606 0
Rb GrowingGSE19898 187137465 187137590 125 0
Rb GrowingGSE19898 187137776 187138091 315 0
Rb QuiescentGSE19898 187137337 187138120 783 0
Rb SenescentGSE19898 187137730 187138182 452 0
Rb shRbSenescenceGSE19898 187137836 187138066 230 0
TAF HelaGSE8489 187134908 187138334 3426 0
TAF k562GSE8489 187133628 187138950 5322 0
VDR GM10861-UnstimGSE22484 187110996 187125857 14861 0
hScc1 BcellGSE12603 187137696 187138501 805 0
hScc1 G2GSE9613 187137846 187138465 619 0
p130 QuiescentGSE19898 187137760 187138828 1068 0
p130 SenescentGSE19898 187137396 187138857 1461 0
p130 shRbQuiescentGSE19898 187137462 187138836 1374 0
p130 shRbSenescentGSE19898 187137508 187138879 1371 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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