AutismKB 2.0

Annotation Detail for MMP25


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Basic Information Top
Gene Symbol:MMP25 ( MMP-25,MMP20,MMP20A,MMPL1,MT-MMP 6,MT-MMP6,MT6-MMP,MT6MMP,MTMMP6 )
Gene Full Name: matrix metallopeptidase 25
Band: 16p13.3
Quick LinksEntrez ID:64386; OMIM: 608482; Uniprot ID:MMP25_HUMAN; ENSEMBL ID: ENSG00000008516; HGNC ID: 14246
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
95Cysteine switch (By similarity).
Location(AA) Modifications Resource
539GPI-anchor amidated alanine (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
41Phosphotyrosine(Jak)HMM predict
84Phosphothreonine(PKC)HMM predict
134Phosphoserine(CK1)HMM predict
268Phosphoserine(ATM)HMM predict
285Phosphothreonine(MAPK)HMM predict
287Phosphotyrosine(Syk)HMM predict
291O-linkedHMM predict
304Phosphoserine(CDC2)HMM predict
304PhosphoserineHMM predict
304Phosphoserine(MAPK)HMM predict
304O-linkedHMM predict
304Phosphoserine(CDK)HMM predict
304Phosphoserine(ATM)HMM predict
306Phosphothreonine(CDK)HMM predict
308Phosphoserine(CDK)HMM predict
308Phosphoserine(CDC2)HMM predict
308O-linkedHMM predict
350Phosphoserine(CDC2)HMM predict
524O-linkedHMM predict
524Phosphothreonine(MAPK)HMM predict
527O-linkedHMM predict
548ProlineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_022468
  • Location:chr16 3036682-3050722
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 3035603 3035847 244 958
FoxA1 MCF7MACSdata 3035481 3035673 192 1106
Rb SenescentGSE19898 3029587 3029844 257 6967
TFAP2C MCF7GSE21234 3035335 3035748 413 1141
hScc1 CdLSGSE12603 3035819 3036895 1076 326
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 3049209 3049532 323 0
CTCF CD4SISSRdata 3049209 3049532 323 0
CTCF G2GSE9613 3048270 3049631 1361 0
NRSF pAbJurkat 3048869 3049185 316 0
PHF8 293TGSE20725 3048871 3050203 1332 0
PHF8 HeLaGSE20725 3048804 3050158 1354 0
Rb SenescentGSE19898 3049836 3049985 149 0
STAT1 IFNSISSRdata 3048969 3050215 1246 0
hScc1 BcellGSE12603 3048234 3049817 1583 0
hScc1 CdLSGSE12603 3048388 3049747 1359 0
p130 QuiescentGSE19898 3049442 3049668 226 0
p130 QuiescentGSE19898 3049704 3050038 334 0
p130 shRbQuiescentGSE19898 3049326 3050099 773 0
p130 shRbSenescentGSE19898 3049522 3049846 324 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018