Annotation Detail for POLR1E

View Evidences	View Variants	View Annotations

Basic Information Top

Gene Symbol:	POLR1E ( FLJ13390,FLJ13970,PAF53,PRAF1,RP11-405L18.3 )
Gene Full Name:	polymerase (RNA) I polypeptide E, 53kDa
Band:	9p13.2
Quick Links	Entrez ID:64425; OMIM: NA; Uniprot ID:RPA49_HUMAN; ENSEMBL ID: ENSG00000137054; HGNC ID: 17631
Relate to Another Database:	SFARIGene; denovo-db

Pathways, Diseases and Drugs

TF binding site

Post Translation Modification

PTM Sites from Uniprot:1 results
Experimental PTM Sites from dbPTM:0 results
Predicted PTM Sites by profile HMM from dbPTM:0 results

Location(AA)	Modification
225	Phosphoserine.

Validated transcription factor binding site by ChIP-Chip and ChIP-Seq

RefSeq ID: NM_022490
Location:chr9 37475944-37493692
strand:+

Upstream the gene:11 results
Downstream the gene:0 results
Inside the gene:10 results

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
CTCF	CD4	GSE12889	37472431	37472546	115	3456
CTCF	CD4	SISSRdata	37472431	37472546	115	3456
ER	Fulvestrant-MCF7	GSE14664	37475690	37475733	43	233
Fos	K562	GSE19551	37475494	37476093	599	151
Oct1	Hela	GSE14283	37475696	37475725	29	234
Rb	Senescent	GSE19898	37475524	37476125	601	120
Rb	shRbSenescence	GSE19898	37475665	37475924	259	150
TFAP2C	MCF7	GSE21234	37475294	37476093	799	251
hScc1	Bcell	GSE12603	37475725	37476093	368	36
p130	Quiescent	GSE19898	37475714	37476046	332	65
p130	Senescent	GSE19898	37475516	37476315	799	29

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
H3ac	HepG2	E	37476166	37478597	2431	0
LIN9	G0	GSE7516	37475725	37476334	609	0
PHF8	293T	GSE20725	37475407	37476543	1136	0
p130	Quiescent	GSE19898	37477251	37477369	118	0
p130	Senescent	GSE19898	37476333	37476716	383	0
p130	Senescent	GSE19898	37477020	37477591	571	0
p130	shRbQuiescent	GSE19898	37476223	37477342	1119	0
p130	shRbSenescent	GSE19898	37475623	37476327	704	0
p130	shRbSenescent	GSE19898	37476990	37477485	495	0
p130	G0	GSE7516	37475905	37476612	707	0

Validated miRNA targets

Cis-Nats regulation

Simple Query:

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

Studies: 1,036
Genes: 1,379
CNVs/SVs: 5,420
SNVs/Indels: 11,669
de novo Mutations: 5,669
Mosaics: 789
Linkage Regions: 172

Paper Collected: 6/30/2018

Last Update: 8/26/2018

Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved