Annotation Detail for SCG5

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Basic Information Top

Gene Symbol:	SCG5 ( 7B2,P7B2,SGNE1,SgV )
Gene Full Name:	secretogranin V (7B2 protein)
Band:	15q13.3
Quick Links	Entrez ID:6447; OMIM: 173120; Uniprot ID:7B2_HUMAN; ENSEMBL ID: ENSG00000166922; HGNC ID: 10816
Relate to Another Database:	SFARIGene; denovo-db

Pathways, Diseases and Drugs

TF binding site

Post Translation Modification

PTM Sites from Uniprot:1 results
Experimental PTM Sites from dbPTM:1 results
Predicted PTM Sites by profile HMM from dbPTM:7 results

Location(AA)	Modification
205	Phosphoserine (By similarity).

Location(AA)	Modification	Resource
31	Phosphothreonine(CDC2)	HMM predict
31	Phosphothreonine(MAPK)	HMM predict
113	Phosphotyrosine(EGFR)	HMM predict
113	Phosphotyrosine(Syk)	HMM predict
113	Sulfotyrosine	HMM predict
169	Phosphotyrosine(INSR)	HMM predict
182	Phosphoserine(PKG)	HMM predict

Validated transcription factor binding site by ChIP-Chip and ChIP-Seq

RefSeq ID: NM_003020
Location:chr15 30721251-30776589
strand:+

Upstream the gene:0 results
Downstream the gene:4 results
Inside the gene:13 results

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
CTCF	G2	GSE9613	30777984	30778243	259	1524
FOXA1	MCF7	GSE15244	30780310	30780551	241	3841
FOXA1	eGFP	GSE10845	30780310	30780551	241	3841
FoxA1	MCF7	MACSdata	30780015	30780325	310	3581

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
CTCF	CD4	GSE12889	30730788	30730990	202	0
CTCF	CD4	GSE12889	30742122	30742458	336	0
CTCF	CD4	SISSRdata	30730788	30730990	202	0
CTCF	CD4	SISSRdata	30742122	30742458	336	0
CTCF	Hela	GSE12889	30742116	30742385	269	0
CTCF	G2	GSE9613	30742070	30742493	423	0
Myc	K562	GSE19551	30730706	30731080	374	0
hScc1	Bcell	GSE12603	30730732	30730965	233	0
hScc1	Bcell	GSE12603	30742070	30742493	423	0
hScc1	Bcell	GSE12603	30751483	30751878	395	0
hScc1	CdLS	GSE12603	30742070	30742493	423	0
p130	shRbQuiescent	GSE19898	30721050	30721588	538	0
p63	keratinocytes	GSE17611	30738687	30739634	947	0

Validated miRNA targets

Cis-Nats regulation

Cluster ID	Plue Type	Plus Gene Name	Plus Chromosome	Plus Start	Plus End	Overlap Length	Minus Type	Minus Gene Name	Minus Chromosome	Minus Star	Minus End	Type
8601	mRNA	SGNE1	chr15	30721251	30776590	13009	EST		chr15	30735576	30748585	Non-exonic Bidirectional (NOB) pairs

Simple Query:

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

Studies: 1,036
Genes: 1,379
CNVs/SVs: 5,420
SNVs/Indels: 11,669
de novo Mutations: 5,669
Mosaics: 789
Linkage Regions: 172

Paper Collected: 6/30/2018

Last Update: 8/26/2018

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