AutismKB 2.0

Annotation Detail for TPSB2


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Basic Information Top
Gene Symbol:TPSB2 ( TPS2,tryptaseB,tryptaseC )
Gene Full Name: tryptase beta 2 (gene/pseudogene)
Band: 16p13.3
Quick LinksEntrez ID:64499; OMIM: 191081; Uniprot ID:TRYB2_HUMAN; ENSEMBL ID: ENSG00000197253; HGNC ID: 14120
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
97Phosphotyrosine (By similarity).
233N-linked (GlcNAc...) (Potential).
Location(AA) Modifications Resource
233N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
14O-linkedHMM predict
96Phosphotyrosine(Abl)HMM predict
97SulfotyrosineHMM predict
132N-linkedHMM predict
146O-linkedHMM predict
219Phosphoserine(PKG)HMM predict
233N-linkedHMM predict
258ThreonineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_024164
  • Location:chr16 1218337-1220185
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
TFAP2C MCF7GSE21234 1220193 1220657 464 240
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 1216615 1217163 548 1449
No data
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018