AutismKB 2.0

Annotation Detail for SH3BP2


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Basic Information Top
Gene Symbol:SH3BP2 ( 3BP2,CRBM,CRPM,FLJ42079,FLJ54978 )
Gene Full Name: SH3-domain binding protein 2
Band: 4p16.3
Quick LinksEntrez ID:6452; OMIM: 602104; Uniprot ID:3BP2_HUMAN; ENSEMBL ID: ENSG00000087266; HGNC ID: 10825
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
210SH3-binding.
278Phosphoserine.
444Phosphoserine (By similarity).
Location(AA) Modifications Resource
174PhosphotyrosinePhospho.ELM 6.0
183PhosphotyrosinePhospho.ELM 6.0
225Phosphoserine (PKC alpha)Phospho.ELM 6.0
278PhosphoserinePhospho.ELM 6.0
Location(AA) Modification Resource
65O-linkedHMM predict
68Phosphoserine(CDC2)HMM predict
68Phosphoserine(CDK)HMM predict
113Phosphoserine(CK2)HMM predict
113PhosphoserineHMM predict
147Phosphoserine(CK1)HMM predict
147Phosphoserine(ATM)HMM predict
165Phosphoserine(CDC2)HMM predict
174SulfotyrosineHMM predict
174Phosphotyrosine(Syk)HMM predict
183SulfotyrosineHMM predict
183Phosphotyrosine(INSR)HMM predict
183Phosphotyrosine(Jak)HMM predict
183Phosphotyrosine(Syk)HMM predict
188Phosphoserine(ATM)HMM predict
211Phosphothreonine(CDK)HMM predict
225Phosphoserine(IKK)HMM predict
273Phosphothreonine(MAPK)HMM predict
273Phosphothreonine(CDC2)HMM predict
278Phosphoserine(PKA)HMM predict
278Phosphoserine(PKG)HMM predict
283O-linkedHMM predict
284O-linkedHMM predict
300Phosphoserine(PKA)HMM predict
302Phosphoserine(CDC2)HMM predict
302Phosphoserine(MAPK)HMM predict
302Phosphoserine(CDK)HMM predict
304O-linkedHMM predict
309Phosphothreonine(MAPK)HMM predict
319O-linkedHMM predict
340Phosphoserine(CDC2)HMM predict
340Phosphoserine(CDK)HMM predict
346O-linkedHMM predict
346O-linkedHMM predict
347O-linkedHMM predict
425Phosphoserine(CDK)HMM predict
427Phosphoserine(PKC)HMM predict
435Phosphoserine(IKK)HMM predict
444Phosphoserine(CK2)HMM predict
448Phosphotyrosine(EGFR)HMM predict
448SulfotyrosineHMM predict
448Phosphotyrosine(Jak)HMM predict
448Phosphotyrosine(Syk)HMM predict
460N-linkedHMM predict
475Phosphoserine(CDC2)HMM predict
475Phosphoserine(MAPK)HMM predict
489N-linkedHMM predict
555TyrosineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_003023
  • Location:chr4 2790338-2810711
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T30-glioblastomaGSE21026 2783238 2783987 749 6726
CTCF G2GSE9613 2771987 2773285 1298 17703
CTCF G2GSE9613 2774236 2774998 762 15722
CTCF G2GSE9613 2775470 2776738 1268 14235
CTCF G2GSE9613 2777957 2778597 640 12062
CTCF G2GSE9613 2780595 2781633 1038 9225
CTCF G2GSE9613 2782456 2784386 1930 6918
CTCF G2GSE9613 2785592 2787063 1471 4011
CTCF G2GSE9613 2787321 2787452 131 2952
CTCF G2GSE9613 2788559 2789107 548 1506
CTCF G2GSE9613 2789851 2790173 322 327
ETS1 JurkatGSE17954 2783207 2784046 839 6712
Fos K562GSE19551 2775111 2775647 536 14960
H3ac HepG2E 2772124 2772777 653 17888
KLF4 hESGSE17917 2789363 2789527 164 894
P300 T30-glioblastomaGSE21026 2783250 2783915 665 6756
TFAP2C MCF7GSE21234 2771543 2772708 1165 18213
TFAP2C MCF7GSE21234 2772725 2773069 344 17442
TFAP2C MCF7GSE21234 2777282 2777724 442 12836
hScc1 BcellGSE12603 2772937 2773285 348 17228
hScc1 BcellGSE12603 2780595 2783041 2446 8521
hScc1 BcellGSE12603 2783740 2784118 378 6410
hScc1 BcellGSE12603 2784562 2784801 239 5657
hScc1 BcellGSE12603 2789613 2790418 805 323
hScc1 G2GSE9613 2775697 2776208 511 14386
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 2791731 2793051 1320 0
CTCF G2GSE9613 2794068 2794274 206 0
CTCF G2GSE9613 2794663 2795002 339 0
CTCF G2GSE9613 2796043 2796705 662 0
CTCF G2GSE9613 2798893 2799614 721 0
CTCF G2GSE9613 2800203 2801844 1641 0
CTCF G2GSE9613 2802196 2802790 594 0
CTCF G2GSE9613 2803257 2803805 548 0
CTCF G2GSE9613 2804979 2805885 906 0
CTCF G2GSE9613 2808110 2808535 425 0
VDR GM10861-stimGSE22484 2805324 2808729 3405 0
hScc1 BcellGSE12603 2795494 2796594 1100 0
hScc1 BcellGSE12603 2799851 2800636 785 0
hScc1 BcellGSE12603 2800980 2801809 829 0
hScc1 BcellGSE12603 2804247 2804669 422 0
hScc1 G2GSE9613 2800305 2801844 1539 0
hScc1 G2GSE9613 2804979 2805885 906 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018