AutismKB 2.0

Annotation Detail for SH3GL2


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Basic Information Top
Gene Symbol:SH3GL2 ( CNSA2,EEN-B1,FLJ20276,FLJ25015,SH3D2A,SH3P4 )
Gene Full Name: SH3-domain GRB2-like 2
Band: 9p22.2
Quick LinksEntrez ID:6456; OMIM: 604465; Uniprot ID:SH3G2_HUMAN; ENSEMBL ID: ENSG00000107295; HGNC ID: 10831
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
75Phosphoserine.
Location(AA) Modifications Resource
75Phosphoserine.Swiss-Prot 53.0
75PhosphoserinePhospho.ELM 6.0
Location(AA) Modification Resource
14Phosphothreonine(PKA)HMM predict
86Phosphotyrosine(EGFR)HMM predict
170Phosphotyrosine(Jak)HMM predict
282Phosphothreonine(CDC2)HMM predict
282Phosphothreonine(MAPK)HMM predict
282Phosphothreonine(CDK)HMM predict
328Phosphotyrosine(Syk)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_003026
  • Location:chr9 17569193-17787119
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Myc hESGSE17917 17568957 17569262 305 84
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 17801115 17801385 270 14131
CTCF CD4SISSRdata 17801115 17801385 270 14131
Oct1 H2O2-HelaGSE14283 17796324 17796351 27 9218
hScc1 BcellGSE12603 17800682 17801378 696 13911
hScc1 CdLSGSE12603 17800682 17801598 916 14021
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
NRSF JurkatGSE13047 17734407 17735654 1247 0
NRSF mAbJurkat 17731623 17734250 2627 0
NRSF mAbJurkat 17734665 17736047 1382 0
NRSF mAbJurkat 17736390 17737515 1125 0
NRSF mAbJurkat 17737985 17738362 377 0
NRSF mAbJurkat 17741027 17741166 139 0
NRSF-mono JurkatQuESTdata 17734574 17735409 835 0
NRSF-poly JurkatQuESTdata 17734574 17735282 708 0
Oct1 H2O2-HelaGSE14283 17725530 17725576 46 0
Oct1 HelaGSE14283 17570684 17570713 29 0
Oct1 HelaGSE14283 17582827 17582859 32 0
Oct1 HelaGSE14283 17596978 17597005 27 0
Oct1 HelaGSE14283 17725534 17725576 42 0
Oct1 HelaGSE14283 17738180 17738232 52 0
P300 T0-glioblastomaGSE21026 17617649 17618066 417 0
SRF HelaGSE8489 17603288 17604757 1469 0
STAT1 HeLaGSE12783 17603194 17606619 3425 0
STAT1 HeLaGSE12783 17620099 17621891 1792 0
STAT1 HeLaGSE12783 17640069 17641391 1322 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018